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The clinical trial is a pivotal and costly process, often spanning multiple years and requiring substantial financial resources. Therefore, the development of clinical trial outcome prediction models aims to exclude drugs likely to fail and…

机器学习 · 计算机科学 2025-01-29 Wenhao Zheng , Liaoyaqi Wang , Dongshen Peng , Hongxia Xu , Yun Li , Hongtu Zhu , Tianfan Fu , Huaxiu Yao

Multimodal clinical prediction is widely used to integrate heterogeneous data such as Electronic Health Records (EHR) and biosignals. However, existing methods tend to rely on static modality integration schemes and simple fusion…

机器学习 · 计算机科学 2026-01-16 Jongseok Kim , Seongae Kang , Jonghwan Shin , Yuhan Lee , Ohyun Jo

Multimodal medical image fusion plays a crucial role in medical diagnosis by integrating complementary information from different modalities to enhance image readability and clinical applicability. However, existing methods mainly follow…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Haozhe Xiang , Han Zhang , Yu Cheng , Xiongwen Quan , Wanwan Huang

Clinical trials are the gold standard for assessing the effectiveness and safety of drugs for treating diseases. Given the vast design space of drug molecules, elevated financial cost, and multi-year timeline of these trials, research on…

机器学习 · 计算机科学 2025-01-14 Yiqing Zhang , Xiaozhong Liu , Fabricio Murai

Foundation models trained on patient electronic health records (EHRs) require tokenizing medical data into sequences of discrete vocabulary items. Existing tokenizers treat medical codes from EHRs as isolated textual tokens. However, each…

计算与语言 · 计算机科学 2025-07-01 Xiaorui Su , Shvat Messica , Yepeng Huang , Ruth Johnson , Lukas Fesser , Shanghua Gao , Faryad Sahneh , Marinka Zitnik

With the emergence of multimodal electronic health records, the evidence for an outcome may be captured across multiple modalities ranging from clinical to imaging and genomic data. Predicting outcomes effectively requires fusion frameworks…

Multimodal clinical prediction faces three challenges: multiple foundation models (FMs) with complementary strengths per modality, pervasive missing modalities at training and test time, and sample-specific variation in modality…

机器学习 · 计算机科学 2026-05-19 Seungik Cho , Anqi Li , Wei Qiu

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing…

机器学习 · 计算机科学 2026-05-06 He Lyu , Huolin Zeng , Junren Wang , Huazhen Yang , Linchao He , Yong Chen , Zhirui Li , Andreas Maier , Siming Bayer , Huan Song

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

计算机视觉与模式识别 · 计算机科学 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

机器学习 · 计算机科学 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Real-world time series exhibit complex and evolving dynamics, making accurate forecasting extremely challenging. Recent multi-modal forecasting methods leverage textual information such as news reports to improve prediction, but most rely…

机器学习 · 计算机科学 2026-01-30 Lige Zhang , Ali Maatouk , Jialin Chen , Leandros Tassiulas , Rex Ying

Healthcare models are transitioning from unimodal prediction toward multimodal reasoning over heterogeneous diagnostic inputs. In computational pathology, for complex tumor subtypes where morphology alone can be challenging to distinguish,…

This study proposes a multi-modal fusion framework Multitrans based on the Transformer architecture and self-attention mechanism. This architecture combines the study of non-contrast computed tomography (NCCT) images and discharge diagnosis…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Danqing Ma , Meng Wang , Ao Xiang , Zongqing Qi , Qin Yang

Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for portal hypertension, but provides variable survival outcomes and frequent overt hepatic encephalopathy (OHE), indicating the necessity of accurate…

计算机视觉与模式识别 · 计算机科学 2025-10-14 Junhao Dong , Dejia Liu , Ruiqi Ding , Zongxing Chen , Yingjie Huang , Zhu Meng , Jianbo Zhao , Zhicheng Zhao , Fei Su

Industrial recommender systems critically depend on high-quality ranking models. However, traditional pipelines still rely on manual feature engineering and scenario-specific architectures, which hinder cross-scenario transfer and…

信息检索 · 计算机科学 2025-10-20 Xianyang Qi , Yuan Tian , Zhaoyu Hu , Zhirui Kuai , Chang Liu , Hongxiang Lin , Lei Wang

Multimodal representation learning has demonstrated remarkable potential in enabling models to process and integrate diverse data modalities, such as text and images, for improved understanding and performance. While the medical domain can…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Shuvendu Roy , Franklin Ogidi , Ali Etemad , Elham Dolatabadi , Arash Afkanpour

With the rapid advancement of Multimodal Large Language Models (MLLMs), an increasing number of researchers are exploring their application in recommendation systems. However, the high latency associated with large models presents a…

信息检索 · 计算机科学 2025-04-29 Junjie Zhou

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

计算与语言 · 计算机科学 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

Predicting multiple heterogeneous biological and medical targets is a challenge for traditional deep learning models. In contrast to single-task learning, in which a separate model is trained for each target, multi-task learning (MTL)…

机器学习 · 计算机科学 2022-05-31 Raquel Aoki , Frederick Tung , Gabriel L. Oliveira

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi
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