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Recently, Graph Convolutional Networks (GCNs) have proven to be a powerful mean for Computer Aided Diagnosis (CADx). This approach requires building a population graph to aggregate structural information, where the graph adjacency matrix…

人工智能 · 计算机科学 2021-06-17 Hao Chen , Fuzhen Zhuang , Li Xiao , Ling Ma , Haiyan Liu , Ruifang Zhang , Huiqin Jiang , Qing He

Deep Graph Neural Networks (GNNs) are useful models for graph classification and graph-based regression tasks. In these tasks, graph pooling is a critical ingredient by which GNNs adapt to input graphs of varying size and structure. We…

机器学习 · 计算机科学 2020-06-25 Yu Guang Wang , Ming Li , Zheng Ma , Guido Montufar , Xiaosheng Zhuang , Yanan Fan

This paper presents HGEN that pioneers ensemble learning for heterogeneous graphs. We argue that the heterogeneity in node types, nodal features, and local neighborhood topology poses significant challenges for ensemble learning,…

机器学习 · 计算机科学 2026-02-05 Jiajun Shen , Yufei Jin , Yi He , Xingquan Zhu

Humans have $23$ pairs of homologous chromosomes. The homologous pairs are almost identical pairs of chromosomes. For the most part, differences in homologous chromosome occur at certain documented positions called single nucleotide…

信息论 · 计算机科学 2015-02-09 Govinda M. Kamath , Eren Şaşoğlu , David Tse

The recent past has seen an increasing interest in Heterogeneous Graph Neural Networks (HGNNs), since many real-world graphs are heterogeneous in nature, from citation graphs to email graphs. However, existing methods ignore a tree…

机器学习 · 计算机科学 2025-04-15 Mingyu Guan , Jack W. Stokes , Qinlong Luo , Fuchen Liu , Purvanshi Mehta , Elnaz Nouri , Taesoo Kim

Graph clustering, aiming to partition nodes of a graph into various groups via an unsupervised approach, is an attractive topic in recent years. To improve the representative ability, several graph auto-encoder (GAE) models, which are based…

机器学习 · 计算机科学 2021-03-16 Hongyuan Zhang , Rui Zhang , Xuelong Li

A pangenome captures the genetic diversity across multiple individuals simultaneously, providing a more comprehensive reference for genome analysis than a single linear genome, which may introduce allele bias. A widely adopted pangenome…

数据结构与算法 · 计算机科学 2026-02-16 Xingfu Li , Yongping Wang

Machine learning on graphs is an important and ubiquitous task with applications ranging from drug design to friendship recommendation in social networks. The primary challenge in this domain is finding a way to represent, or encode, graph…

社会与信息网络 · 计算机科学 2018-04-11 William L. Hamilton , Rex Ying , Jure Leskovec

We consider the problem of detecting and estimating the strength of association between a trait of interest and alleles or haplotypes in a small genomic region (e.g. a gene or a gene complex), when no direct information on that region is…

应用统计 · 统计学 2008-04-11 Rodrigo Labouriau , Poul Sørensen , Helle R. Juul-Madsen

Attributed graph clustering is challenging as it requires joint modelling of graph structures and node attributes. Recent progress on graph convolutional networks has proved that graph convolution is effective in combining structural and…

机器学习 · 计算机科学 2019-06-05 Xiaotong Zhang , Han Liu , Qimai Li , Xiao-Ming Wu

Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large…

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

定量方法 · 定量生物学 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

Recent developed graph-based methods for diagnosing brain disorders using functional connectivity highly rely on predefined brain atlases, but overlook the rich information embedded within atlases and the confounding effects of site and…

机器学习 · 计算机科学 2025-10-16 Qianqian Liao , Wuque Cai , Hongze Sun , Dongze Liu , Duo Chen , Dezhong Yao , Daqing Guo

Background: Haplotypes, the ordered lists of single nucleotide variations that distinguish chromosomal sequences from their homologous pairs, may reveal an individual's susceptibility to hereditary and complex diseases and affect how our…

社会与信息网络 · 计算机科学 2019-11-28 Abishek Sankararaman , Haris Vikalo , François Baccelli

While human action recognition has witnessed notable achievements, multimodal methods fusing RGB and skeleton modalities still suffer from their inherent heterogeneity and fail to fully exploit the complementary potential between them. In…

计算机视觉与模式识别 · 计算机科学 2025-12-29 Zeyu Liang , Hailun Xia , Naichuan Zheng

Despite recent advances in representation learning in hypercomplex (HC) space, this subject is still vastly unexplored in the context of graphs. Motivated by the complex and quaternion algebras, which have been found in several contexts to…

机器学习 · 计算机科学 2022-02-22 Tuan Le , Marco Bertolini , Frank Noé , Djork-Arné Clevert

Graph neural networks have become the default choice by practitioners for graph learning tasks such as graph classification and node classification. Nevertheless, popular graph neural network models still struggle to capture higher-order…

机器学习 · 计算机科学 2024-11-27 Davide Buffelli , Farzin Soleymani , Bastian Rieck

Graph is a useful data structure to model various real life aspects like email communications, co-authorship among researchers, interactions among chemical compounds, and so on. Supporting such real life interactions produce a knowledge…

数据结构与算法 · 计算机科学 2016-11-11 Kifayat Ullah Khan , Waqas Nawaz , Young-Koo Lee

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

定量方法 · 定量生物学 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

Hypergraphs, with their capacity to depict high-order relationships, have emerged as a significant extension of traditional graphs. Although Graph Neural Networks (GNNs) have remarkable performance in graph representation learning, their…

机器学习 · 计算机科学 2024-11-07 Khaled Mohammed Saifuddin , Mehmet Emin Aktas , Esra Akbas