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Genomic Foundation Models (GFMs), such as Evolutionary Scale Modeling (ESM), have demonstrated significant success in variant effect prediction. However, their adversarial robustness remains largely unexplored. To address this gap, we…

密码学与安全 · 计算机科学 2025-12-04 Huixin Zhan , Clovis Barbour , Jason H. Moore

Engineered image-based biomarkers offer a clinically interpretable alternative to black-box AI in computational pathology, yet their discovery remains largely intuition-driven, guided by fragmented literature rather than rigorous biological…

Large language models (LLMs) have achieved remarkable progress, yet their internal mechanisms remain largely opaque, posing a significant challenge to their safe and reliable deployment. Sparse autoencoders (SAEs) have emerged as a…

计算与语言 · 计算机科学 2026-02-11 Jiaojiao Han , Wujiang Xu , Mingyu Jin , Mengnan Du

Spatial transcriptomics enables spatial gene expression profiling, motivating computational models that capture spatially conditioned regulatory relationships. We introduce SAGE-FM, a lightweight spatial transcriptomics foundation model…

机器学习 · 计算机科学 2026-01-23 Xianghao Zhan , Jingyu Xu , Yuanning Zheng , Zinaida Good , Olivier Gevaert

AI agents are increasingly deployed in production, yet their security evaluations remain bottlenecked by manual red-teaming or static benchmarks that fail to model adaptive, multi-turn adversaries. We propose NAAMSE, an evolutionary…

人工智能 · 计算机科学 2026-03-10 Kunal Pai , Parth Shah , Harshil Patel

As Large Language Models are rapidly deployed across diverse applications from healthcare to financial advice, safety evaluation struggles to keep pace. Current benchmarks focus on single-turn interactions with generic policies, failing to…

密码学与安全 · 计算机科学 2025-10-28 Madhur Jindal , Hari Shrawgi , Parag Agrawal , Sandipan Dandapat

We propose the first unified adversarial attack benchmark for Genomic Foundation Models (GFMs), named GenoArmory. Unlike existing GFM benchmarks, GenoArmory offers the first comprehensive evaluation framework to systematically assess the…

机器学习 · 计算机科学 2025-10-14 Haozheng Luo , Chenghao Qiu , Yimin Wang , Shang Wu , Jiahao Yu , Zhenyu Pan , Weian Mao , Haoyang Fang , Hao Xu , Han Liu , Binghui Wang , Yan Chen

While deep learning approaches have shown remarkable performance in many imaging tasks, most of these methods rely on availability of large quantities of data. Medical image data, however, is scarce and fragmented. Generative Adversarial…

图像与视频处理 · 电气工程与系统科学 2022-06-07 Padmaja Jonnalagedda , Brent Weinberg , Jason Allen , Taejin L. Min , Shiv Bhanu , Bir Bhanu

Attack graphs (AG) are used to assess pathways availed by cyber adversaries to penetrate a network. State-of-the-art approaches for AG generation focus mostly on deriving dependencies between system vulnerabilities based on network scans…

密码学与安全 · 计算机科学 2021-10-15 Azqa Nadeem , Sicco Verwer , Shanchieh Jay Yang

Software vulnerabilities are a primary threat to modern infrastructure. While static analysis and Graph Neural Networks have long served as the foundation for vulnerability detection, the emergence of Large Language Models (LLMs) has…

密码学与安全 · 计算机科学 2026-04-22 Zhengyang Shan , Xu Qian , Jiayun Xin , Minghui Xu , Yue Zhang , Zhen Yang , Hao Wu , Xiuzhen Cheng

Agent-based models (ABMs) stand as an essential paradigm for proposing and validating hypothetical solutions or policies aimed at addressing challenges posed by complex systems and achieving various objectives. This process demands…

计算与语言 · 计算机科学 2024-04-02 Tong Niu , Weihao Zhang , Rong Zhao

The rapid deployment of large language model (LLM)-based agents introduces a new class of risks, driven by their capacity for autonomous planning, multi-step tool integration, and emergent interactions. It raises some risk factors for…

多智能体系统 · 计算机科学 2025-12-04 Rafflesia Khan , Declan Joyce , Mansura Habiba

The rapid proliferation of the Internet of Things (IoT) continues to expose critical security vulnerabilities, necessitating the development of efficient and robust intrusion detection systems (IDS). Machine learning-based intrusion…

密码学与安全 · 计算机科学 2025-09-11 Jing Chen , Onat Gungor , Zhengli Shang , Tajana Rosing

Large Language Models (LLMs) have shown impressive capabilities across various tasks but remain vulnerable to meticulously crafted jailbreak attacks. In this paper, we identify a critical safety gap: while LLMs are adept at detecting…

计算与语言 · 计算机科学 2025-05-20 Peng Ding , Jun Kuang , Zongyu Wang , Xuezhi Cao , Xunliang Cai , Jiajun Chen , Shujian Huang

We present a hybrid framework for adaptive insider-threat detection that tightly integrates multi-agent simulation (MAS), layered Security Information and Event Management (SIEM) correlation, behavioral and communication forensics,…

密码学与安全 · 计算机科学 2026-01-09 Firdous Kausar , Asmah Muallem , Naw Safrin Sattar , Mohamed Zakaria Kurdi

The development of Large Language Models (LLMs) has catalyzed automation in customer service, yet benchmarking their performance remains challenging. Existing benchmarks predominantly rely on static paradigms and single-dimensional metrics,…

人工智能 · 计算机科学 2026-04-13 Ling Shi , Yuqin Dai , Ziyin Wang , Ning Gao , Wei Zhang , Chaozheng Wang , Yujie Wang , Wei He , Jinpeng Wang , Deiyi Xiong

The rapid iteration cycles of modern live-service games make regression testing indispensable for maintaining quality and stability. However, existing regression testing approaches face critical limitations, especially in common gray-box…

软件工程 · 计算机科学 2025-12-02 Jinyu Cai , Jialong Li , Nianyu Li , Zhenyu Mao , Mingyue Zhang , Kenji Tei

The promising potential of AI and network convergence in improving networking performance and enabling new service capabilities has recently attracted significant interest. Existing network AI solutions, while powerful, are mainly built…

网络与互联网体系结构 · 计算机科学 2025-05-13 Yong Xiao , Guangming Shi , Ping Zhang

Deep search agents, which aim to answer complex questions requiring reasoning across multiple documents, can significantly speed up the information-seeking process. Collecting human annotations for this application is prohibitively…

Large Language Models (LLMs) achieve strong performance on standard knowledge evaluation benchmarks, yet recent work shows that their knowledge capabilities remain brittle under question variants that test the same knowledge in different…

计算与语言 · 计算机科学 2026-05-13 Xiaoyuan Li , Yuzhe Wang , Moxin Li , Keqin Bao , Rui Men , Yichang Zhang , Dayiheng Liu , Wenjie Wang , Fuli Feng
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