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In recent years, several machine learning approaches have been proposed to predict gene expression and epigenetic signals from the DNA sequence alone. These models are often used to deduce, and, to some extent, assess putative new…

基因组学 · 定量生物学 2023-04-26 Laurent Bréhélin

With the intensification of global aging, health management of the elderly has become a focus of social attention. This study designs and implements a smart elderly care service model to address issues such as data diversity, health status…

人工智能 · 计算机科学 2024-12-04 Qian Guo , Peiyuan Chen

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

机器学习 · 计算机科学 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Under the current regulatory framework for data protections, the protection of human rights writ large and the corresponding outcomes are regulated largely independently from the data and tools that both threaten those rights and are needed…

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

机器学习 · 统计学 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

With the exponential advancement of business technology in recent years, data-driven decision making has become the core of most industries. With the rise of new privacy regulations such as the General Data Protection Regulation in the…

计算机与社会 · 计算机科学 2020-04-02 Johannes M. van Hulst , Mattia Zeni , Alexander Kröller , Cassandra Moons , Pierluigi Casale

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Many current Internet services rely on inferences from models trained on user data. Commonly, both the training and inference tasks are carried out using cloud resources fed by personal data collected at scale from users. Holding and using…

机器学习 · 计算机科学 2018-04-04 Sandra Servia-Rodriguez , Liang Wang , Jianxin R. Zhao , Richard Mortier , Hamed Haddadi

Many modern statistical analysis and machine learning applications require training models on sensitive user data. Under a formal definition of privacy protection, differentially private algorithms inject calibrated noise into the…

机器学习 · 统计学 2025-04-01 Yifei Xiong , Nianqiao Phyllis Ju , Sanguo Zhang

It is commonly observed that the data are scattered everywhere and difficult to be centralized. The data privacy and security also become a sensitive topic. The laws and regulations such as the European Union's General Data Protection…

机器学习 · 计算机科学 2020-02-19 Yang Liu , Mingxin Chen , Wenxi Zhang , Junbo Zhang , Yu Zheng

Genetic data collection has become ubiquitous, producing genetic information about health, ancestry, and social traits. However, unregulated use, especially amid evolving scientific understanding, poses serious privacy and discrimination…

计算机与社会 · 计算机科学 2025-06-03 Vivek Ramanan , Ria Vinod , Cole Williams , Sohini Ramachandran , Suresh Venkatasubramanian

Prediction rule ensembles (PREs) are a relatively new statistical learning method, which aim to strike a balance between predictive accuracy and interpretability. Starting from a decision tree ensemble, like a boosted tree ensemble or a…

应用统计 · 统计学 2023-10-02 Marjolein Fokkema , Carolin Strobl

Recent applications of machine learning (ML) reveal a noticeable shift from its use for predictive modeling in the sense of a data-driven construction of models mainly used for the purpose of prediction (of ground-truth facts) to its use…

机器学习 · 计算机科学 2021-12-16 Eyke Hüllermeier

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

机器学习 · 统计学 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

密码学与安全 · 计算机科学 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Regulations for privacy protection aim to protect individuals from the unauthorized storage, processing, and transfer of their personal data but oftentimes fail in providing helpful support for understanding these regulations. To better…

As a multitude of capable machine learning (ML) models become widely available in forms such as open-source software and public APIs, central questions remain regarding their use in real-world applications, especially in high-stakes…

机器学习 · 计算机科学 2024-06-03 Dimitris Bertsimas , Matthew Peroni

Existing studies show that regulation is a major barrier to global economic integration. Nonetheless, identifying and measuring regulatory barriers remains a challenging task for scholars. I propose a novel approach to quantify regulatory…

应用统计 · 统计学 2023-01-27 Haosen Ge

While many online services provide privacy policies for end users to read and understand what personal data are being collected, these documents are often lengthy and complicated. As a result, the vast majority of users do not read them at…

A prediction model is most useful if it generalizes beyond the development data with external validations, but to what extent should it generalize remains unclear. In practice, prediction models are externally validated using data from very…

机器学习 · 计算机科学 2023-04-11 Yilin Ning , Victor Volovici , Marcus Eng Hock Ong , Benjamin Alan Goldstein , Nan Liu