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Trustworthy interpretation of deep learning models is critical for neuroimaging applications, yet commonly used Explainable AI (XAI) methods lack rigorous validation, risking misinterpretation. We performed the first large-scale, systematic…

机器学习 · 计算机科学 2025-08-07 Nys Tjade Siegel , James H. Cole , Mohamad Habes , Stefan Haufe , Kerstin Ritter , Marc-André Schulz

Computed tomography image segmentation of complex abdominal aortic aneurysms (AAA) often fails because the models assign internal focus to irrelevant structures or do not focus on thin, low-contrast targets. Where the model looks is the…

计算机视觉与模式识别 · 计算机科学 2026-03-27 Abu Noman Md Sakib , Merjulah Roby , Zijie Zhang , Satish Muluk , Mark K. Eskandari , Ender A. Finol

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Explainability domain generalization and rare class reliability are critical challenges in medical AI where deep models often fail under real world distribution shifts and exhibit bias against infrequent clinical conditions This paper…

人工智能 · 计算机科学 2026-01-06 Midhat Urooj , Ayan Banerjee , Sandeep Gupta

Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…

计算机视觉与模式识别 · 计算机科学 2020-07-07 Quande Liu , Qi Dou , Pheng-Ann Heng

The success of deep learning models deployed in the real world depends critically on their ability to generalize well across diverse data domains. Here, we address a fundamental challenge with selective classification during automated…

计算机视觉与模式识别 · 计算机科学 2023-11-29 Anuj Srivastava , Karm Patel , Pradeep Shenoy , Devarajan Sridharan

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

图像与视频处理 · 电气工程与系统科学 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

计算机视觉与模式识别 · 计算机科学 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

This study explores the integration of multiple Explainable AI (XAI) techniques to enhance the interpretability of deep learning models for brain tumour detection. A custom Convolutional Neural Network (CNN) was developed and trained on the…

人工智能 · 计算机科学 2026-02-06 Patrick McGonagle , William Farrelly , Kevin Curran

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

机器学习 · 计算机科学 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

Alzheimer's Disease (AD) is the world leading cause of dementia, a progressively impairing condition leading to high hospitalization rates and mortality. To optimize the diagnostic process, numerous efforts have been directed towards the…

图像与视频处理 · 电气工程与系统科学 2025-01-20 Davide Coluzzi , Valentina Bordin , Massimo Walter Rivolta , Igor Fortel , Liang Zhang , Alex Leow , Giuseppe Baselli

Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

计算机视觉与模式识别 · 计算机科学 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…

计算机视觉与模式识别 · 计算机科学 2025-12-05 Chenlin Xu , Lei Zhang , Lituan Wang , Xinyu Pu , Pengfei Ma , Guangwu Qian , Zizhou Wang , Yan Wang

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

计算机视觉与模式识别 · 计算机科学 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

计算机视觉与模式识别 · 计算机科学 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

The current study investigated the use of Explainable Artificial Intelligence (XAI) to improve the accuracy of brain tumor segmentation in MRI images, with the goal of assisting physicians in clinical decision-making. The study focused on…

计算机视觉与模式识别 · 计算机科学 2025-10-10 Ming Jie Ong , Sze Yinn Ung , Sim Kuan Goh , Jimmy Y. Zhong

Explainable Artificial Intelligence (XAI) is an emerging research topic of machine learning aimed at unboxing how AI systems' black-box choices are made. This research field inspects the measures and models involved in decision-making and…

人工智能 · 计算机科学 2021-02-04 Guang Yang , Qinghao Ye , Jun Xia

While deep learning models become more widespread, their ability to handle unseen data and generalize for any scenario is yet to be challenged. In medical imaging, there is a high heterogeneity of distributions among images based on the…

图像与视频处理 · 电气工程与系统科学 2025-05-01 Eduardo H. P. Pooch , Pedro L. Ballester , Rodrigo C. Barros

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

计算机视觉与模式识别 · 计算机科学 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu
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