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Foundation diffusion models can generate photorealistic natural images, but adapting them to medical imaging remains challenging. In medical adaptation, limited labeled data can exacerbate hallucination-like and clinically implausible…

计算机视觉与模式识别 · 计算机科学 2026-05-14 Yunsung Chung , Alex El Darzi , Carlo El Khoury , Han Feng , Nassir Marrouche , Jihun Hamm

The integration of artificial intelligence into digital pathology has the potential to automate and improve various tasks, such as image analysis and diagnostic decision-making. Yet, the inherent variability of tissues, together with the…

图像与视频处理 · 电气工程与系统科学 2023-02-14 Ariel Larey , Nati Daniel , Eliel Aknin , Yael Fisher , Yonatan Savir

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Content generation modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and task-oriented generation across diverse diagnostic tasks.…

图像与视频处理 · 电气工程与系统科学 2025-09-09 Yuan Zhang , Xinfeng Zhang , Xiaoming Qi , Xinyu Wu , Feng Chen , Guanyu Yang , Huazhu Fu

Building high-quality datasets for specialized tasks is a time-consuming and resource-intensive process that often requires specialized domain knowledge. We propose Corpus Retrieval and Augmentation for Fine-Tuning (CRAFT), a method for…

计算与语言 · 计算机科学 2025-12-08 Ingo Ziegler , Abdullatif Köksal , Desmond Elliott , Hinrich Schütze

Deep learning models for chest X-ray diagnosis are constrained by limited coverage of clinically meaningful concept combinations in publicly available training datasets. While synthetic image generation has been explored to increase data…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved…

图像与视频处理 · 电气工程与系统科学 2022-03-30 Yunlong Zhang , Xin Lin , Yihong Zhuang , LiyanSun , Yue Huang , Xinghao Ding , Guisheng Wang , Lin Yang , Yizhou Yu

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

图像与视频处理 · 电气工程与系统科学 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

Generative models have been applied in the medical imaging domain for various image recognition and synthesis tasks. However, a more controllable and interpretable image synthesis model is still lacking yet necessary for important…

图像与视频处理 · 电气工程与系统科学 2021-11-15 Jiarong Ye , Yuan Xue , Peter Liu , Richard Zaino , Keith Cheng , Xiaolei Huang

Diffusion models have emerged as a dominant approach for text-to-image generation. Key components such as the human preference alignment and classifier-free guidance play a crucial role in ensuring generation quality. However, their…

计算机视觉与模式识别 · 计算机科学 2025-06-10 Minghao Fu , Guo-Hua Wang , Liangfu Cao , Qing-Guo Chen , Zhao Xu , Weihua Luo , Kaifu Zhang

Recent work has shown that inference-time reasoning and reflection can improve text-to-image generation without retraining. However, existing approaches often rely on implicit, holistic critiques or unconstrained prompt rewrites, making…

计算机视觉与模式识别 · 计算机科学 2026-01-22 V. Kovalev , A. Kuvshinov , A. Buzovkin , D. Pokidov , D. Timonin

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng

In computational pathology, understanding and generation have evolved along disparate paths: advanced understanding models already exhibit diagnostic-level competence, whereas generative models largely simulate pixels. Progress remains…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Minghao Han , Yichen Liu , Yizhou Liu , Zizhi Chen , Jingqun Tang , Xuecheng Wu , Dingkang Yang , Lihua Zhang

The scarcity of high-quality, labelled retinal imaging data, which presents a significant challenge in the development of machine learning models for ophthalmology, hinders progress in the field. Existing methods for synthesising Colour…

图像与视频处理 · 电气工程与系统科学 2025-07-18 Junzhi Ning , Cheng Tang , Kaijing Zhou , Diping Song , Lihao Liu , Ming Hu , Wei Li , Huihui Xu , Yanzhou Su , Tianbin Li , Jiyao Liu , Jin Ye , Sheng Zhang , Yuanfeng Ji , Junjun He

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural…

计算机视觉与模式识别 · 计算机科学 2024-02-20 Yuxuan Sun , Chenglu Zhu , Sunyi Zheng , Kai Zhang , Lin Sun , Zhongyi Shui , Yunlong Zhang , Honglin Li , Lin Yang

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

图像与视频处理 · 电气工程与系统科学 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

计算机视觉与模式识别 · 计算机科学 2025-06-03 Kanishk Choudhary

The scarcity of annotated Magnetic Resonance Imaging (MRI) tumor data presents a major obstacle to accurate and automated tumor segmentation. While existing data synthesis methods offer promising solutions, they often suffer from key…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Nayu Dong , Townim Chowdhury , Hieu Phan , Mark Jenkinson , Johan Verjans , Zhibin Liao

Vision-language foundation models have shown great promise in computational pathology but remain primarily data-driven, lacking explicit integration of medical knowledge. We introduce KEEP (KnowledgE-Enhanced Pathology), a foundation model…

图像与视频处理 · 电气工程与系统科学 2026-01-28 Xiao Zhou , Luoyi Sun , Dexuan He , Wenbin Guan , Ge Wang , Ruifen Wang , Lifeng Wang , Xiaojun Yuan , Xin Sun , Ya Zhang , Kun Sun , Yanfeng Wang , Weidi Xie

Automatic thin-prep cytologic test (TCT) screening can assist pathologists in finding cervical abnormality towards accurate and efficient cervical cancer diagnosis. Current automatic TCT screening systems mostly involve abnormal cervical…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Zhenrong Shen , Manman Fei , Xin Wang , Jiangdong Cai , Sheng Wang , Lichi Zhang , Qian Wang
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