相关论文: Quantum-enhanced biosensing enables earlier detect…
The field of quantum sensing aims at improving the detection and estimation of classical parameters that are encoded in physical systems by resorting to quantum sources of light and quantum detection strategies. The same approach can be…
Absorption measurement is an exceptionally versatile tool for many applications in science and engineering. For absorption measurements using laser beams of light, the sensitivity is theoretically limited by the shot noise due to the…
Label-free optical microscopy through absorption or scattering spectroscopy provides fundamental insights across biology and materials science, yet its sensitivity remains fundamentally limited by photon shot noise. While recent…
In this work a quantum imaging setup based on undetected squeezed photons is employed for metrological applications such as sensitive phase measurement and quantum imaging. In spite of the traditional quantum imaging with undetected…
Among the known resources of quantum metrology, one of the most practical and efficient is squeezing. Squeezed states of atoms and light improve the sensing of the phase, magnetic field, polarization, mechanical displacement. They promise…
Squeezed states of light enable quantum-enhanced measurements but are limited by optical loss, particularly at 2 um where photodiode efficiency is low. We report the first loss-tolerant, audio-band squeezed light detection at 1984 nm by…
Quantum noise places a fundamental limit on the per photon sensitivity attainable in optical measurements. This limit is of particular importance in biological measurements, where the optical power must be constrained to avoid damage to the…
Optical phase estimation is a vital measurement primitive that is used to perform accurate measurements of various physical quantities like length, velocity and displacements. The precision of such measurements can be largely enhanced by…
Much of our progress in understanding microscale biology has been powered by advances in microscopy. For instance, super-resolution microscopes allow the observation of biological structures at near-atomic-scale resolution, while…
Nonlinear optical microscopy techniques have emerged as a set of successful tools for biological imaging. Stimulated emission microscopy belongs to a small subset of pump-probe techniques which can image non-fluorescent samples without…
The tantalizing promise of quantum computational speedup in solving certain problems has been strongly supported by recent experimental evidence from a high-fidelity 53-qubit superconducting processor1 and Gaussian boson sampling (GBS) with…
Analyzing the kinetics of biological processes plays a significant role in understanding fundamental cellular functions. Many physics-based technologies used to study such processes are limited by the shot noise inherent to the coherent…
Brillouin microscopy is an emerging label-free imaging technique to assess local viscoelastic properties. Quantum-enhanced stimulated Brillouin scattering is demonstrated for the first time using low power continuous-wave lasers at 795~nm.…
We present a computational live bacteria detection system that periodically captures coherent microscopy images of bacterial growth inside a 60 mm diameter agar-plate and analyzes these time-lapsed holograms using deep neural networks for…
Absorption spectroscopy is a widely used technique that permits the detection and characterization of gas species at low concentrations. We propose a sensing strategy combining the advantages of frequency modulation spectroscopy with the…
Photon-number squeezing and correlations enable measurement of absorption with an accuracy exceeding that of the shot-noise limit. However, sub-shot noise imaging and sensing based on these methods require high detection efficiency, which…
The quantum statistical fluctuations of the electromagnetic field establish a limit, known as the shot-noise limit, on the sensitivity of optical measurements performed with classical technologies. However, quantum technologies are not…
Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…
Stimulated Raman scattering (SRS) microscopy has emerged as a powerful technique for probing the spatiotemporal dynamics of molecular bonds with exceptional sensitivity, resolution, and speed. However, classically, its performance remains…
The quantum noise of light fundamentally limits optical phase sensors. A semiclassical picture attributes this noise to the random arrival time of photons from a coherent light source such as a laser. An engineered source of squeezed states…