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The blood-brain barrier (BBB) serves as a protective barrier that separates the brain from the circulatory system, regulating the passage of substances into the central nervous system. Assessing the BBB permeability of potential drugs is…

定量方法 · 定量生物学 2024-09-10 Shivesh Prakash

Predicting whether a molecule can cross the blood-brain barrier (BBB) is a key step in early-stage neuro-pharmaceutical design, directly influencing the efficiency and success rate of drug development. Traditional methods based on…

定量方法 · 定量生物学 2026-03-16 Zihan Yang , Yuchen Xiao

In this paper, we investigate distributed inference schemes, over binary-valued Markov random fields, which are realized by the belief propagation (BP) algorithm. We first show that a decision variable obtained by the BP algorithm in a…

信息论 · 计算机科学 2019-09-19 Younes Abdi , Tapani Ristaniemi

Boundary representation (B-rep) is the industry standard for computer-aided design (CAD). While deep learning shows promise in processing B-rep models, existing methods suffer from a representation gap: continuous approaches offer…

机器学习 · 计算机科学 2026-02-10 Yuanxu Sun , Yuezhou Ma , Haixu Wu , Guanyang Zeng , Muye Chen , Jianmin Wang , Mingsheng Long

Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Mattia Litrico , Francesco Guarnera , Mario Valerio Giuffrida , Daniele Ravì , Sebastiano Battiato

Belief Propagation (BP) is an important message-passing algorithm for various reasoning tasks over graphical models, including solving the Constraint Optimization Problems (COPs). It has been shown that BP can achieve state-of-the-art…

人工智能 · 计算机科学 2022-09-27 Yanchen Deng , Shufeng Kong , Caihua Liu , Bo An

Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…

Deep neural networks (DNNs) offer significant promise for improving breast cancer diagnosis in medical imaging. However, these models are highly susceptible to adversarial attacks--small, imperceptible changes that can mislead…

计算机视觉与模式识别 · 计算机科学 2024-12-16 Yasamin Medghalchi , Moein Heidari , Clayton Allard , Leonid Sigal , Ilker Hacihaliloglu

We present Bayesian Diffusion Models (BDM), a prediction algorithm that performs effective Bayesian inference by tightly coupling the top-down (prior) information with the bottom-up (data-driven) procedure via joint diffusion processes. We…

计算机视觉与模式识别 · 计算机科学 2024-04-23 Haiyang Xu , Yu Lei , Zeyuan Chen , Xiang Zhang , Yue Zhao , Yilin Wang , Zhuowen Tu

Belief Propagation (BP) is a message-passing algorithm for approximate inference over Probabilistic Graphical Models (PGMs), finding many applications such as computer vision, error-correcting codes, and protein-folding. While general, the…

分布式、并行与集群计算 · 计算机科学 2019-09-26 Mark Van der Merwe , Vinu Joseph , Ganesh Gopalakrishnan

With the growing interest in foundation models for brain signals, graph-based pretraining has emerged as a promising paradigm for learning transferable representations from connectome data. However, existing contrastive and masked…

机器学习 · 计算机科学 2026-03-10 Xinxu Wei , Rong Zhou , Lifang He , Yu Zhang

It has been proposed by many researchers that combining deep neural networks with graphical models can create more efficient and better regularized composite models. The main difficulties in implementing this in practice are associated with…

计算机视觉与模式识别 · 计算机科学 2020-03-16 Patrick Knöbelreiter , Christian Sormann , Alexander Shekhovtsov , Friedrich Fraundorfer , Thomas Pock

We propose enforcing constraints on Model-Based Diffusion by introducing emerging barrier functions inspired by interior point methods. We demonstrate that the standard Model-Based Diffusion algorithm can lead to catastrophic performance…

机器人学 · 计算机科学 2026-03-10 Raghav Mishra , Ian R. Manchester

Depth estimation is crucial for intelligent systems, enabling applications from autonomous navigation to augmented reality. While traditional stereo and active depth sensors have limitations in cost, power, and robustness, dual-pixel (DP)…

计算机视觉与模式识别 · 计算机科学 2025-08-04 Kunal Swami , Debtanu Gupta , Amrit Kumar Muduli , Chirag Jaiswal , Pankaj Kumar Bajpai

Diffusion models demonstrate remarkable capabilities in capturing complex data distributions and have achieved compelling results in many generative tasks. While they have recently been extended to dense prediction tasks such as depth…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Haorui Ji , Taojun Lin , Hongdong Li

Predicting clinical outcomes from brain networks in large-scale neuroimaging cohorts such as the Adolescent Brain Cognitive Development (ABCD) study requires effectively integrating functional connectivity (FC) and structural connectivity…

计算工程、金融与科学 · 计算机科学 2026-02-11 Zhenyu Lei , Aiying Zhang , Song Wang , Han Fan , Jundong Li

Radiation therapy is the primary method used to treat cancer in the clinic. Its goal is to deliver a precise dose to the planning target volume (PTV) while protecting the surrounding organs at risk (OARs). However, the traditional workflow…

图像与视频处理 · 电气工程与系统科学 2024-04-10 Tara Gheshlaghi , Shahabedin Nabavi , Samire Shirzadikia , Mohsen Ebrahimi Moghaddam , Nima Rostampour

In this work, we introduce Brain Latent Progression (BrLP), a novel spatiotemporal disease progression model based on latent diffusion. BrLP is designed to predict the evolution of diseases at the individual level on 3D brain MRIs. Existing…

计算机视觉与模式识别 · 计算机科学 2025-07-15 Lemuel Puglisi , Daniel C. Alexander , Daniele Ravì

Existing methods for arterial blood pressure (BP) estimation directly map the input physiological signals to output BP values without explicitly modeling the underlying temporal dependencies in BP dynamics. As a result, these models suffer…

机器学习 · 计算机科学 2018-01-16 Peng Su , Xiao-Rong Ding , Yuan-Ting Zhang , Jing Liu , Fen Miao , Ni Zhao

Can our brain signals faithfully reflect the original visual stimuli, even including high-frequency details? Although human perceptual and cognitive capacities enable us to process and remember visual information, these abilities are…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Haitao Wu , Qing Li , Changqing Zhang , Zhen He , Xiaomin Ying
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