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Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major cause of dementia. Structural MRI is widely used to analyze AD-related brain atrophy; however, most deep learning methods rely on computationally expensive 3D…

计算机视觉与模式识别 · 计算机科学 2026-04-28 Towhidul Islam , Mufti Mahmud

In recent years, deformable medical image registration techniques have made significant progress. However, existing models still lack efficiency in parallel extraction of coarse and fine-grained features. To address this, we construct a new…

计算机视觉与模式识别 · 计算机科学 2025-05-12 Ying Zhang , Shuai Guo , Chenxi Sun , Yuchen Zhu , Jinhai Xiang

Electroencephalography (EEG) analysis stands at the forefront of neuroscience and artificial intelligence research, where foundation models are reshaping the traditional EEG analysis paradigm by leveraging their powerful representational…

人机交互 · 计算机科学 2025-08-25 Hongqi Li , Yitong Chen , Yujuan Wang , Weihang Ni , Haodong Zhang

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

计算机视觉与模式识别 · 计算机科学 2018-10-26 Juan Manuel Fernández Montenegro

Accurate medical image segmentation is essential for clinical diagnosis and treatment planning. While recent interactive foundation models (e.g., nnInteractive) enhance generalization through large-scale multimodal pretraining, they still…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Ziyu Zhang , Yi Yu , Simeng Zhu , Ahmed Aly , Yunhe Gao , Ning Gu , Yuan Xue

Despite the significant potential of Foundation Models (FMs) in medical imaging, their application to prognosis prediction remains challenging due to data scarcity, class imbalance, and task complexity, which limit their clinical adoption.…

计算机视觉与模式识别 · 计算机科学 2026-01-16 Filippo Ruffini , Elena Mulero Ayllon , Linlin Shen , Paolo Soda , Valerio Guarrasi

Surgical segmentation is pivotal for scene understanding yet remains hindered by annotation scarcity and semantic inconsistency across diverse procedures. Existing approaches typically fine-tune natural foundation models (e.g., SAM) with…

计算机视觉与模式识别 · 计算机科学 2025-12-10 Qing Xu , Kun Yuan , Yuxiang Luo , Yuhao Zhai , Wenting Duan , Nassir Navab , Zhen Chen

Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

机器学习 · 计算机科学 2019-10-22 David Wood , James Cole , Thomas Booth

Due to the widespread use of complex machine learning models in real-world applications, it is becoming critical to explain model predictions. However, these models are typically black-box deep neural networks, explained post-hoc via…

机器学习 · 计算机科学 2022-10-20 Filip Radenovic , Abhimanyu Dubey , Dhruv Mahajan

Functional connectivity, as estimated using resting state fMRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of…

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

计算机视觉与模式识别 · 计算机科学 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression…

机器学习 · 计算机科学 2018-12-07 Vipul Satone , Rachneet Kaur , Faraz Faghri , Mike A Nalls , Andrew B Singleton , Roy H Campbell

Ultrasound imaging is widely used in clinical diagnosis due to its non-invasive nature and real-time capabilities. However, traditional ultrasound diagnostics relies heavily on physician expertise and is often hampered by suboptimal image…

图像与视频处理 · 电气工程与系统科学 2025-12-18 Yuncheng Jiang , Chun-Mei Feng , Jinke Ren , Jun Wei , Zixun Zhang , Yiwen Hu , Yunbi Liu , Rui Sun , Xuemei Tang , Juan Du , Xiang Wan , Yong Xu , Bo Du , Xin Gao , Guangyu Wang , Shaohua Zhou , Shuguang Cui , Zhen Li

Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…

计算机视觉与模式识别 · 计算机科学 2019-10-15 Gururaj Awate , Sunil Bangare , G Pradeepini , S Patil

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Advances in genomic medicine accelerate the identi cation of mutations in disease-associated genes, but the pathogenicity of many mutations remains unknown, hindering their use in diagnostics and clinical decision-making. Predictive AI…

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution. Our approach combines a spatio-temporal description of both processes into a…

神经元与认知 · 定量生物学 2019-05-27 Raphaël Sivera , Hervé Delingette , Marco Lorenzi , Xavier Pennec , Nicholas Ayache

Medical artificial intelligence (AI) systems frequently lack systematic domain expertise integration, potentially compromising diagnostic reliability. This study presents an ontology-based framework for bone disease diagnosis, developed in…

人工智能 · 计算机科学 2025-06-06 Loan Dao , Ngoc Quoc Ly

In recent years, neuroimaging has undergone a paradigm shift, moving away from the traditional brain mapping approach toward developing integrated, multivariate brain models that can predict categories of mental events. However, large…

应用统计 · 统计学 2022-09-19 Guoqing Wang , Abhirup Datta , Martin A. Lindquist