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Synthesizing high-quality mathematical reasoning data without human priors remains a significant challenge. Current approaches typically rely on seed data mutation or simple prompt engineering, often suffering from mode collapse and limited…

计算与语言 · 计算机科学 2026-04-14 Zixiong Yu , Jun Rao , Guhan Chen , Songtao Tian , Bohan Li , Jiansheng Wei , Min Zhang , Xiaojun Meng

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

计算与语言 · 计算机科学 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Spreadsheets are ubiquitous across the World Wide Web, playing a critical role in enhancing work efficiency across various domains. Large language model (LLM) has been recently attempted for automatic spreadsheet manipulation but has not…

人工智能 · 计算机科学 2025-03-04 Yibin Chen , Yifu Yuan , Zeyu Zhang , Yan Zheng , Jinyi Liu , Fei Ni , Jianye Hao , Hangyu Mao , Fuzheng Zhang

Recent progress in multimodal reasoning has enabled agents that interpret imagery, connect it with language, and execute structured analytical tasks. Extending these capabilities to remote sensing remains challenging, as models must reason…

Large Language Models (LLMs) can extend their parameter knowledge limits by adopting the Tool-Integrated Reasoning (TIR) paradigm. However, existing LLM-based agent training framework often focuses on answers' accuracy, overlooking specific…

人工智能 · 计算机科学 2026-01-21 Yifei Chen , Guanting Dong , Zhicheng Dou

Large Language Models (LLMs) have shown promise in automating code generation and software engineering tasks, yet they often struggle with complex, multi-file projects due to context limitations and knowledge gaps. We propose a novel…

软件工程 · 计算机科学 2025-08-13 Muhammad Haseeb

Analyzing whole-slide images (WSIs) requires an iterative, evidence-driven reasoning process that parallels how pathologists dynamically zoom, refocus, and self-correct while collecting the evidence. However, existing computational…

计算机视觉与模式识别 · 计算机科学 2025-11-24 Jingyun Chen , Linghan Cai , Zhikang Wang , Yi Huang , Songhan Jiang , Shenjin Huang , Hongpeng Wang , Yongbing Zhang

Existing tool-augmented large language models (LLMs) encounter significant challenges when processing complex queries. Current frameworks such as ReAct are prone to local optimization traps due to their reliance on incremental…

人工智能 · 计算机科学 2025-11-26 Xiaolong Wei , Yuehu Dong , Xingliang Wang , Xingyu Zhang , Zhejun Zhao , Dongdong Shen , Long Xia , Dawei Yin

Training AI models has always been challenging, especially when there is a need for custom models to provide personalized services. Algorithm engineers often face a lengthy process to iteratively develop models tailored to specific business…

人工智能 · 计算机科学 2023-11-27 Haoyuan Li , Hao Jiang , Tianke Zhang , Zhelun Yu , Aoxiong Yin , Hao Cheng , Siming Fu , Yuhao Zhang , Wanggui He

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

人工智能 · 计算机科学 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Large Language Models (LLMs) have demonstrated great potential in complex reasoning tasks, yet they fall short when tackling more sophisticated challenges, especially when interacting with environments through generating executable actions.…

计算与语言 · 计算机科学 2025-02-25 Yuqi Zhu , Shuofei Qiao , Yixin Ou , Shumin Deng , Shiwei Lyu , Yue Shen , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large reasoning models have demonstrated strong problem-solving abilities, yet real-world tasks often require external tools and long-horizon interactions. Existing agent frameworks typically follow predefined workflows, which limit…

人工智能 · 计算机科学 2026-02-06 Xiaoxi Li , Wenxiang Jiao , Jiarui Jin , Guanting Dong , Jiajie Jin , Yinuo Wang , Hao Wang , Yutao Zhu , Ji-Rong Wen , Yuan Lu , Zhicheng Dou

Recent progress in large language models (LLMs) has enabled substantial advances in solving mathematical problems. However, existing benchmarks often fail to reflect the complexity of real-world problems, which demand open-ended,…

人工智能 · 计算机科学 2025-05-22 Cheng Qian , Hongyi Du , Hongru Wang , Xiusi Chen , Yuji Zhang , Avirup Sil , Chengxiang Zhai , Kathleen McKeown , Heng Ji

Developing AI models that are useful in clinical practice, requires efficient collaboration between clinicians and AI developers. This poses a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI…

计算机视觉与模式识别 · 计算机科学 2026-05-28 Zihao Zhao , Frederik Hauke , Juliana De Castilhos , Mathis Bode , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Large language models (LLMs) have shown great potential in the medical domain. However, existing models still fall short when faced with complex medical diagnosis task in the real world. This is mainly because they lack sufficient reasoning…

人工智能 · 计算机科学 2025-08-06 Qi Peng , Jialin Cui , Jiayuan Xie , Yi Cai , Qing Li

Complex clinical decision making often fails not because a model lacks facts, but because it cannot reliably select and apply the right procedural knowledge and the right prior example at the right reasoning step. We frame clinical question…

信息检索 · 计算机科学 2026-03-03 Junda Wang , Zonghai Tao , Hansi Zeng , Zhichao Yang , Hamed Zamani , Hong Yu

Therapeutic development is a costly and high-risk endeavor that is often plagued by high failure rates. To address this, we introduce TxGemma, a suite of efficient, generalist large language models (LLMs) capable of therapeutic property…

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Clinical dialogue represents a complex duality requiring both the empathetic fluency of natural conversation and the rigorous precision of evidence-based medicine. While Large Language Models possess unprecedented linguistic capabilities,…

其他定量生物学 · 定量生物学 2025-12-02 Xiaoquan Zhi , Hongke Zhao , Likang Wu , Chuang Zhao , Hengshu Zhu

The efficacy of AI agents in healthcare research is hindered by their reliance on static, predefined strategies. This creates a critical limitation: agents can become better tool-users but cannot learn to become better strategic planners, a…

人工智能 · 计算机科学 2025-08-08 Huiya Zhao , Yinghao Zhu , Zixiang Wang , Yasha Wang , Junyi Gao , Liantao Ma