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The analysis of the demographic transition of the past century and a half, using both empirical data and mathematical models, has rendered a wealth of well-established facts, including the dramatic increases in life expectancy. Despite…

种群与进化 · 定量生物学 2018-07-02 Albert Solé-Ribalta , Javier Borge-Holthoefer

Author's early work on aging is developed to yield a relationship between life spans and the velocity of aging. The mathematical analysis shows that the mean extent of the advancement of aging throughout one's life is conserved, or…

种群与进化 · 定量生物学 2007-05-23 Kazumi Suematsu

At the physiological level, aging is neither rigid nor unchangeable. Instead, the molecular and mechanisms driving aging are sufficiently plastic that a variety of diverse interventions--dietary, pharmaceutical, and genetic--have been…

定量方法 · 定量生物学 2018-08-28 Nicholas Stroustrup

The Health State Function theory is applied to find a quantitative estimate of the Human Development Stages by defining and calculating the specific age groups and subgroups. Early and late adolescence stages, first, second and third stages…

种群与进化 · 定量生物学 2013-01-08 Christos H Skiadas , Charilaos Skiadas

There is sustained and widespread interest in understanding the limit, if any, to the human lifespan. Apart from its intrinsic and biological interest, changes in survival in old age have implications for the sustainability of social…

应用统计 · 统计学 2021-04-19 Léo R. Belzile , Anthony C. Davison , Jutta Gampe , Holger Rootzén , Dmitrii Zholud

We develop a unified framework for the measurement and valuation of health and productivity. Within this framework, we characterize evaluation functions allowing for compromises between the classical quality-adjusted life years (QALYs) and…

理论经济学 · 经济学 2024-12-30 Kristian S. Hansen , Juan D. Moreno-Ternero , Lars P. Østerdal

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

神经元与认知 · 定量生物学 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

The existence of an upper limit to the human lifespan has been widely debated, with studies offering both supporting and opposing evidence. Using unique individual-level death and population records for individuals aged 90 and older in…

应用统计 · 统计学 2026-04-10 Jens Robben , Torsten Kleinow

We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move…

数理金融 · 定量金融 2018-11-27 Huaxiong Huang , Moshe A. Milevsky , Thomas S. Salisbury

Does the human lifespan have an impenetrable biological upper limit which ultimately will stop further increase in life lengths? This question is important for understanding aging, and for society, and has led to intense controversies.…

应用统计 · 统计学 2017-08-08 Holger Rootzén , Dmitrii Zholud

Labor share, the fraction of economic output accrued as wages, is inexplicably declining in industrialized countries. Whilst numerous prior works attempt to explain the decline via economic factors, our novel approach links the decline to…

综合经济学 · 经济学 2024-01-05 B. N. Kausik

Human aging is marked by a steady rise in the risk of dying with age-a process demographers call senescence. Over the past century, life expectancy has risen dramatically, but is this because we are aging slower, or simply starting it…

应用统计 · 统计学 2026-04-13 Silvio Cabral Patricio

The chronological age used in demography describes the linear evolution of the life of a living being. The chronological age cannot give precise information about the exact developmental stage or aging processes an organism has reached. On…

偏微分方程分析 · 数学 2023-10-02 Jacques Demongeot , Pierre Magal

The development of sport performances in the future is a subject of myth and disagreement among experts. As arguments favoring and opposing such methodology were discussed, other publications empirically showed that the past development of…

其他统计学 · 统计学 2014-01-30 Geoffroy Berthelot

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

定量方法 · 定量生物学 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

In order to understand the phenomenon of longevity in biological world, the relationship between the potential of longevity and the structural complexity of an organism is analyzed. I. The potential of longevity is the maximum lifespan of…

组织与器官 · 定量生物学 2018-05-28 Jicun Wang-Michelitsch , Thomas M Michelitsch

Aging includes both continuous gradual decline from microscopic mechanisms together with major deficit onset events such as morbidity, disability and ultimately death. These deficit events are stochastic, obscuring the connection between…

定量方法 · 定量生物学 2025-12-25 Glen Pridham , Kenneth Rockwood , Andrew Rutenberg

How self-organized networks develop, mature and degenerate is a key question for sociotechnical, cyberphysical and biological systems with potential applications from tackling violent extremism through to neurological diseases. So far, it…

物理与社会 · 物理学 2017-06-05 M. Zheng , Z. Cao , Y. Vorobyeva , P. Manrique , C. Song , N. F. Johnson

Human life expectancy has dramatically improved over the course of the last century. Although this reflects a global improvement in sanitation and medical care, this also implies that more people suffer from diseases that typically manifest…

其他定量生物学 · 定量生物学 2022-07-11 Alexis Rapin , Maroun Bou Sleiman , Johan Auwerx

Following the recent publication of our book on Exploring the Health State of a Population by Dynamic Modeling Methods in The Springer Series on Demographic Methods and Population Analysis (DOI 10.1007/978-3-319-65142-2) we provide this…

定量方法 · 定量生物学 2017-11-28 Christos H Skiadas , Charilaos Skiadas
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