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相关论文: Optimizing Stroke Risk Prediction: A Machine Learn…

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Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

计算机视觉与模式识别 · 计算机科学 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Timely assessment of compound toxicity is one of the biggest challenges facing the pharmaceutical industry today. A significant proportion of compounds identified as potential leads are ultimately discarded due to the toxicity they induce.…

机器学习 · 统计学 2018-06-13 Mikhail Zaslavskiy , Simon Jégou , Eric W. Tramel , Gilles Wainrib

Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…

We develop a deep learning model, ABioSPATH, to predict the one-year risk of ischemic stroke (IS) in atrial fibrillation (AF) patients. The model integrates drug-protein-disease pathways and real-world clinical data of AF patients to…

定量方法 · 定量生物学 2024-08-27 Zhiheng Lyu , Jiannan Yang , Zhongzhi Xu , Weilan Wang , Weibin Cheng , Kwok-Leung Tsui , Gary Tse , Qingpeng Zhang

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Acute Coronary Syndromes (ACS), including ST-segment elevation myocardial infarctions (STEMI) and non-ST-segment elevation myocardial infarctions (NSTEMI), remain a leading cause of mortality worldwide. Traditional cardiovascular risk…

人工智能 · 计算机科学 2025-04-29 Xin Zhang , Liangxiu Han , Stephen White , Saad Hassan , Philip A Kalra , James Ritchie , Carl Diver , Jennie Shorley

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

机器学习 · 计算机科学 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Explainable Artificial Intelligence (XAI) has been presented as the critical component for unlocking the potential of machine learning in mental health screening (MHS). However, a persistent lab-to-clinic gap remains. Current XAI…

计算与语言 · 计算机科学 2025-10-17 Ratna Kandala , Akshata Kishore Moharir , Divya Arvinda Nayak

Explainable Artificial Intelligence (XAI) has been identified as a viable method for determining the importance of features when making predictions using Machine Learning (ML) models. In this study, we created models that take an…

定量方法 · 定量生物学 2021-12-28 Isaac Ronald Ward , Ling Wang , Juan lu , Mohammed Bennamoun , Girish Dwivedi , Frank M Sanfilippo

Heterogeneous treatment effect (HTE) estimation is critical in medical research. It provides insights into how treatment effects vary among individuals, which can provide statistical evidence for precision medicine. While most existing…

机器学习 · 统计学 2025-04-25 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Algorithmic solutions have significant potential to improve decision-making across various domains, from healthcare to e-commerce. However, the widespread adoption of these solutions is hindered by a critical challenge: the lack of…

机器学习 · 计算机科学 2025-03-11 Zuzanna Bączek , Michał Bizoń , Aneta Pawelec , Piotr Sankowski

The increasing penetration of renewable generation introduces uncertainty into power systems, challenging traditional deterministic optimization methods. Chance-constrained optimization offers an approach to balancing cost and risk;…

最优化与控制 · 数学 2025-11-06 Amir Bahador Javadi , Amin Kargarian

Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…

Dynamic predictions for longitudinal and time-to-event outcomes have become a versatile tool in precision medicine. Our work is motivated by the application of dynamic predictions in the decision-making process for primary biliary…

The primary aim of this paper is to comprehend, assess, and analyze the role, relevance, and efficiency of machine learning models in predicting heart disease risks using clinical data. While the importance of heart disease risk prediction…

Machine learning offers great potential for automated prediction of post-stroke symptoms and their response to rehabilitation. Major challenges for this endeavour include the very high dimensionality of neuroimaging data, the relatively…

Purpose Predicting the progression of MCI to Alzheimer's disease is an important step in reducing the progression of the disease. Therefore, many methods have been introduced for this task based on deep learning. Among these approaches, the…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Atefe Aghaei , Mohsen Ebrahimi Moghaddam

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…

人工智能 · 计算机科学 2025-09-24 Xiuyi Fan

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

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