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Multimodal language models (MLMs) show promise for clinical decision support and diagnostic reasoning, raising the prospect of end-to-end automated medical image interpretation. However, clinicians are highly selective in adopting AI tools;…

Multimodal Large Language Models are increasingly applied to biomedical imaging, yet scientific reasoning for microscopy remains limited by the scarcity of large-scale, high-quality training data. We introduce MicroVQA++, a three-stage,…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Manyu Li , Ruian He , Chenxi Ma , Weimin Tan , Bo Yan

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Recent advances in large vision-language models (LVLMs) have demonstrated strong performance on general-purpose medical tasks. However, their effectiveness in specialized domains such as dentistry remains underexplored. In particular,…

计算机视觉与模式识别 · 计算机科学 2025-09-12 Jing Hao , Yuxuan Fan , Yanpeng Sun , Kaixin Guo , Lizhuo Lin , Jinrong Yang , Qi Yong H. Ai , Lun M. Wong , Hao Tang , Kuo Feng Hung

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Multimodal large models have shown great potential in automating pathology image analysis. However, current multimodal models for gastrointestinal pathology are constrained by both data quality and reasoning transparency: pervasive noise…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Minxi Ouyang , Lianghui Zhu , Yaqing Bao , Qiang Huang , Jingli Ouyang , Tian Guan , Xitong Ling , Jiawen Li , Song Duan , Wenbin Dai , Li Zheng , Xuemei Zhang , Yonghong He

The recent swift development of LLMs like GPT-4, Gemini, and GPT-3.5 offers a transformative opportunity in medicine and healthcare, especially in digital diagnostics. This study evaluates each model diagnostic abilities by interpreting a…

计算与语言 · 计算机科学 2024-05-14 Gaurav Kumar Gupta , Aditi Singh , Sijo Valayakkad Manikandan , Abul Ehtesham

Whole Slide Image (WSI) MLLMs are difficult to build and deploy because gigapixel slides induce thousands of visual tokens, while only a small fraction of regions is diagnostically relevant. Existing slide-level pathology MLLMs typically…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Qingqiao Hu , Weimin Lyu , Meilong Xu , Kehan Qi , Xiaoling Hu , Saumya Gupta , Jiawei Zhou , Chao Chen

Whole slide image (WSI) analysis presents significant computational challenges due to the massive number of patches in gigapixel images. While transformer architectures excel at modeling long-range correlations through self-attention, their…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Zhengrui Guo , Qichen Sun , Jiabo Ma , Lishuang Feng , Jinzhuo Wang , Hao Chen

Despite significant advancements in general AI, its effectiveness in the medical domain is limited by the lack of specialized medical knowledge. To address this, we formulate GMAI-VL-5.5M, a multimodal medical dataset created by converting…

计算机视觉与模式识别 · 计算机科学 2025-03-28 Tianbin Li , Yanzhou Su , Wei Li , Bin Fu , Zhe Chen , Ziyan Huang , Guoan Wang , Chenglong Ma , Ying Chen , Ming Hu , Yanjun Li , Pengcheng Chen , Xiaowei Hu , Zhongying Deng , Yuanfeng Ji , Jin Ye , Yu Qiao , Junjun He

This paper investigates visual analogical reasoning in large multimodal models (LMMs) compared to human adults and children. A "visual analogy" is an abstract rule inferred from one image and applied to another. While benchmarks exist for…

计算机视觉与模式识别 · 计算机科学 2025-12-05 Eunice Yiu , Maan Qraitem , Anisa Noor Majhi , Charlie Wong , Yutong Bai , Shiry Ginosar , Alison Gopnik , Kate Saenko

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities.…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Honglong Yang , Shanshan Song , Yi Qin , Lehan Wang , Haonan Wang , Xinpeng Ding , Qixiang Zhang , Bodong Du , Xiaomeng Li

Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…

计算机视觉与模式识别 · 计算机科学 2024-10-31 Zijie Fang , Yifeng Wang , Ye Zhang , Zhi Wang , Jian Zhang , Xiangyang Ji , Yongbing Zhang

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking…

Gastrointestinal (GI) diseases represent a clinically significant burden, necessitating precise diagnostic approaches to optimize patient outcomes. Conventional histopathological diagnosis suffers from limited reproducibility and diagnostic…

Multimodal Aspect-Based Sentiment Analysis (MABSA) aims to extract aspect terms and their corresponding sentiment polarities from multimodal information, including text and images. While traditional supervised learning methods have shown…

计算与语言 · 计算机科学 2024-11-26 Shezheng Song

Seeing clearly with high resolution is a foundation of Large Multimodal Models (LMMs), which has been proven to be vital for visual perception and reasoning. Existing works usually employ a straightforward resolution upscaling method, where…

计算机视觉与模式识别 · 计算机科学 2024-06-17 Yi-Fan Zhang , Qingsong Wen , Chaoyou Fu , Xue Wang , Zhang Zhang , Liang Wang , Rong Jin

The shift towards end-to-end deep learning has brought unprecedented advances in many areas of computer vision. However, deep neural networks are trained on images with resolutions that rarely exceed $1,000 \times 1,000$ pixels. The growing…

计算机视觉与模式识别 · 计算机科学 2022-04-19 Neofytos Dimitriou , Ognjen Arandjelovic

Recent pathological foundation models have substantially advanced visual representation learning and multimodal interaction. However, most models still rely on a static inference paradigm in which whole-slide images are processed once to…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Shengyi Hua , Jianfeng Wu , Tianle Shen , Kangzhe Hu , Zhongzhen Huang , Shujuan Ni , Zhihong Zhang , Yuan Li , Zhe Wang , Xiaofan Zhang