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Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

Pseudoprogression (PsP) occurs in 20-30% of patients with glioblastoma multiforme (GBM) after receiving the standard treatment. In the course of post-treatment magnetic resonance imaging (MRI), PsP exhibits similarities in shape and…

计算机视觉与模式识别 · 计算机科学 2020-07-01 Meiyu Li , Hailiang Tang , Michael D. Chan , Xiaobo Zhou , Xiaohua Qian

Pseudoprogression (PsP) is an imitation of true tumor progression (TTP) in patients with glioblastoma multiform (GBM). Differentiating them is a challenging and time-consuming task for radiologists. Although deep neural networks can…

组织与器官 · 定量生物学 2019-02-27 Xiaoming Liu , Michael D. Chan , Xiaobo Zhou , Xiaohua Qian

Glioblastoma (GBM) is an aggressive primary brain tumor with a median survival of approximately 15 months. In clinical practice, the Stupp protocol serves as the standard first-line treatment. However, patients exhibit highly heterogeneous…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Alexandre G. Leclercq , Sébastien Bougleux , Noémie N. Moreau , Alexis Desmonts , Romain Hérault , Aurélien Corroyer-Dulmont

Differentiating tumor progression (TP) from treatment-related necrosis (TN) is critical for clinical management decisions in glioblastoma (GBM). Dynamic FDG PET (dPET), an advance from traditional static FDG PET, may prove advantageous in…

图像与视频处理 · 电气工程与系统科学 2023-03-01 Tonmoy Hossain , Zoraiz Qureshi , Nivetha Jayakumar , Thomas Eluvathingal Muttikkal , Sohil Patel , David Schiff , Miaomiao Zhang , Bijoy Kundu

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

机器学习 · 计算机科学 2026-02-13 Ankita Paul , Wenyi Wang

Objective: To report imaging protocol and scheduling variance in routine care of glioblastoma patients in order to demonstrate challenges of integrating deep-learning models in glioblastoma care pathways. Additionally, to understand the…

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Glioblastoma brain tumors are highly malignant and often require early detection and accurate segmentation for effective treatment. We are proposing two deep learning models in this paper, namely UNet and Deeplabv3, for the detection and…

图像与视频处理 · 电气工程与系统科学 2024-09-02 Utkarsh Maurya , Appisetty Krishna Kalyan , Swapnil Bohidar , S. Sivakumar

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

机器学习 · 计算机科学 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek

Tumor burden assessment by magnetic resonance imaging (MRI) is central to the evaluation of treatment response for glioblastoma. This assessment is complex to perform and associated with high variability due to the high heterogeneity and…

Precise automated delineation of post-operative gross tumor volume in glioblastoma cases is challenging and time-consuming owing to the presence of edema and the deformed brain tissue resulting from the surgical tumor resection. To develop…

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Glioblastoma, a highly aggressive brain tumor with diverse molecular and pathological features, poses a diagnostic challenge due to its heterogeneity. Accurate diagnosis and assessment of this heterogeneity are essential for choosing the…

图像与视频处理 · 电气工程与系统科学 2025-07-25 Juexin Zhang , Ying Weng , Ke Chen

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

医学物理 · 物理学 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Glioblastomas are the most aggressive type of glioma, having a 5-year survival rate of 6.9%. Treatment typically involves surgery, followed by radiotherapy and chemotherapy, and frequent magnetic resonance imaging (MRI) scans to monitor…

图像与视频处理 · 电气工程与系统科学 2025-06-05 Ana Matoso , Catarina Passarinho , Marta P. Loureiro , José Maria Moreira , Patrícia Figueiredo , Rita G. Nunes

Early detection of brain tumors through magnetic resonance imaging (MRI) is essential for timely treatment, yet access to diagnostic facilities remains limited in remote areas. Gliomas, the most common primary brain tumors, arise from the…

图像与视频处理 · 电气工程与系统科学 2024-12-11 Khush Mendiratta , Shweta Singh , Pratik Chattopadhyay
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