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Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

计算与语言 · 计算机科学 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

人工智能 · 计算机科学 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

人工智能 · 计算机科学 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Explainable disease diagnosis, which leverages patient information (e.g., signs and symptoms) and computational models to generate probable diagnoses and reasonings, offers clear clinical values. However, when clinical notes encompass…

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

计算与语言 · 计算机科学 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

人工智能 · 计算机科学 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

Large Language Models (LLMs) have achieved significant advancements, but the increasing complexity of tasks and higher performance demands highlight the need for continuous improvement. Some approaches utilize synthetic data generated by…

人工智能 · 计算机科学 2025-06-23 Haokun Zhao , Jinyi Han , Jiaqing Liang , Yanghua Xiao , Xiaojun Meng , Jiansheng Wei

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

人工智能 · 计算机科学 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Entropy-based confidence signals are increasingly leveraged to improve reasoning in large language models (LLMs), yet existing approaches treat confidence as a static quantity -- typically aggregated over tokens. We show that the…

机器学习 · 计算机科学 2026-03-09 Chenghua Zhu , Siyan Wu , Xiangkang Zeng , Zishan Xu , Zhaolu Kang , Yifu Guo , Yuquan Lu , Junduan Huang , Guojing Zhou

Large Language Models (LLMs) are fluent but prone to hallucinations, producing answers that appear plausible yet are unsupported by available evidence. This failure is especially problematic in high-stakes domains where decisions must be…

计算与语言 · 计算机科学 2026-03-23 J. Ben Tamo , Yuxing Lu , Benoit L. Marteau , Micky C. Nnamdi , May D. Wang

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

计算与语言 · 计算机科学 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Recent advances in large language models (LLMs) have enabled promising progress in diagnosis prediction from electronic health records (EHRs). However, existing LLM-based approaches tend to overfit to historically observed diagnoses, often…

计算与语言 · 计算机科学 2026-04-14 Hengyu Zhang , Xuyun Zhang , Pengxiang Zhan , Linhao Luo , Hang Lv , Yanchao Tan , Shirui Pan , Carl Yang

Large language models (LLMs) encounter difficulties in knowledge-intensive multi-step reasoning (KIMSR) tasks. One challenge is how to effectively extract and represent rationale evidence. The current methods often extract semantically…

计算与语言 · 计算机科学 2025-05-23 Kexin Zhang , Junlan Chen , Daifeng Li , Yuxuan Zhang , Yangyang Feng , Bowen Deng , Weixu Chen

An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive…

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

人工智能 · 计算机科学 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen

Early detection of depression from social media data offers a valuable opportunity for timely intervention. However, this task poses significant challenges, requiring both professional medical knowledge and the development of accurate and…

计算与语言 · 计算机科学 2025-03-20 Xiangyong Chen , Xiaochuan Lin

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Large language models (LLMs) are increasingly used to extract clinical data from electronic health records (EHRs), offering significant improvements in scalability and efficiency for real-world data (RWD) curation in oncology. However, the…

Improving the accessibility of psychotherapy with the aid of Large Language Models (LLMs) is garnering a significant attention in recent years. Recognizing cognitive distortions from the interviewee's utterances can be an essential part of…

计算与语言 · 计算机科学 2024-03-22 Sehee Lim , Yejin Kim , Chi-Hyun Choi , Jy-yong Sohn , Byung-Hoon Kim
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