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Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…

计算机与社会 · 计算机科学 2017-11-20 Anand Avati , Kenneth Jung , Stephanie Harman , Lance Downing , Andrew Ng , Nigam H. Shah

Objective: Machine learning algorithms are now widely used in predicting acute events for clinical applications. While most of such prediction applications are developed to predict the risk of a particular acute event at one hospital, few…

World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved…

人工智能 · 计算机科学 2026-02-04 Linjie Mu , Zhongzhen Huang , Yannian Gu , Shengqian Qin , Shaoting Zhang , Xiaofan Zhang

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

机器学习 · 计算机科学 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Substance overdose mortality in the United States claimed over 80,000 lives in 2023, with the COVID-19 pandemic exacerbating existing trends through healthcare disruptions and behavioral changes. Estimating excess mortality, defined as…

机器学习 · 计算机科学 2025-12-29 Sukanya Krishna , Marie-Laure Charpignon , Maimuna Majumder

Standard approaches for uncertainty quantification in cardiovascular modeling pose challenges due to the large number of uncertain inputs and the significant computational cost of realistic three-dimensional simulations. We propose an…

定量方法 · 定量生物学 2020-04-20 Casey M. Fleeter , Gianluca Geraci , Daniele E. Schiavazzi , Andrew M. Kahn , Alison L. Marsden

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Developing predictive modelling solutions for risk estimation is extremely challenging in health-care informatics. Risk estimation involves integration of heterogeneous clinical sources having different representation from different…

机器学习 · 计算机科学 2016-09-30 Priyanka H U , Vivek R

Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing…

定量方法 · 定量生物学 2020-05-21 Xi Yang , Yan Gong , Nida Waheed , Keith March , Jiang Bian , William R. Hogan , Yonghui Wu

In healthcare, the highest risk individuals for morbidity and mortality are rarely those with the greatest modifiable risk. By contrast, many machine learning formulations implicitly attend to the highest risk individuals. We focus on this…

机器学习 · 统计学 2019-11-15 Yoonjung Kim , Jeremy C. Weiss

Globally, cardiovascular diseases (CVDs) are the leading cause of mortality, accounting for an estimated 17.9 million deaths annually. One critical clinical objective is the early detection of CVDs using electrocardiogram (ECG) data, an…

信号处理 · 电气工程与系统科学 2024-01-25 Siyang Wu

We developed and validated TRisk, a Transformer-based AI model predicting 36-month mortality in heart failure patients by analysing temporal patient journeys from UK electronic health records (EHR). Our study included 403,534 heart failure…

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

机器学习 · 统计学 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

Identifying patients who will be discharged within 24 hours can improve hospital resource management and quality of care. We studied this problem using eight years of Electronic Health Records (EHR) data from Stanford Hospital. We fit…

Objective: This study aimed to evaluate which voice features can predict health deterioration in patients with chronic HF. Background: Heart failure (HF) is a chronic condition with progressive deterioration and acute decompensations, often…

Ischemic heart disease (IHD), particularly in its chronic stable form, is a subtle pathology due to its silent behavior before developing in unstable angina, myocardial infarction or sudden cardiac death. Machine learning techniques applied…

信号处理 · 电气工程与系统科学 2020-11-20 Giulia Silveri , Marco Merlo , Luca Restivo , Gianfranco Sinagra , Agostino Accardo

AI-powered stethoscopes offer a promising alternative for screening rheumatic heart disease (RHD), particularly in regions with limited diagnostic infrastructure. Early detection is vital, yet echocardiography, the gold standard tool,…

Currently, many researchers and analysts are working toward medical diagnosis enhancement for various diseases. Heart disease is one of the common diseases that can be considered a significant cause of mortality worldwide. Early detection…

机器学习 · 计算机科学 2023-06-02 Salahaldeen Rababa , Asma Yamin , Shuxia Lu , Ashraf Obaidat

Machine learning systems trained on electronic health records (EHRs) increasingly guide treatment decisions, but their reliability depends on the critical assumption that patients follow the prescribed treatments recorded in EHRs. Using EHR…

机器学习 · 计算机科学 2025-04-22 Zhongyuan Liang , Arvind Suresh , Irene Y. Chen

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

定量方法 · 定量生物学 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen