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Background: Discovering potential drug-drug interactions (DDIs) is a long-standing challenge in clinical treatments and drug developments. Recently, deep learning techniques have been developed for DDI prediction. However, they generally…

机器学习 · 计算机科学 2024-03-20 Yaqing Wang , Zaifei Yang , Quanming Yao

Since multidrug combination is widely applied, the accurate prediction of drug-drug interaction (DDI) is becoming more and more critical. In our method, we use graph to represent drug-drug interaction: nodes represent drug; edges represent…

机器学习 · 计算机科学 2022-09-01 Haifan zhou , Wenjing Zhou , Junfeng Wu

Multi-modal intent detection aims to utilize various modalities to understand the user's intentions, which is essential for the deployment of dialogue systems in real-world scenarios. The two core challenges for multi-modal intent detection…

计算与语言 · 计算机科学 2024-01-02 Shijue Huang , Libo Qin , Bingbing Wang , Geng Tu , Ruifeng Xu

In recent years, Large Language Models (LLMs) have demonstrated remarkable capabilities in understanding and solving mathematical problems, leading to advancements in various fields. We propose an LLM-embodied path planning framework for…

机器人学 · 计算机科学 2024-07-08 Xiangrui Kong , Wenxiao Zhang , Jin Hong , Thomas Braunl

Goal-oriented de novo molecule design, namely generating molecules with specific property or substructure constraints, is a crucial yet challenging task in drug discovery. Existing methods, such as Bayesian optimization and reinforcement…

计算工程、金融与科学 · 计算机科学 2025-02-28 Chuanliu Fan , Ziqiang Cao , Zicheng Ma , Nan Yu , Yimin Peng , Jun Zhang , Yiqin Gao , Guohong Fu

Large language models (LLMs) have been widely adopted to enrich the semantic representation of textual item information in recommender systems. However, existing linear autoencoders (LAEs) that incorporate textual information rely on sparse…

信息检索 · 计算机科学 2025-08-27 Jaewan Moon , Seongmin Park , Jongwuk Lee

Large Language Models (LLMs) increasingly require processing long text sequences, but GPU memory limitations force difficult trade-offs between memory capacity and bandwidth. While HBM-based acceleration offers high bandwidth, its capacity…

硬件体系结构 · 计算机科学 2025-04-25 Qingyuan Liu , Liyan Chen , Yanning Yang , Haocheng Wang , Dong Du , Zhigang Mao , Naifeng Jing , Yubin Xia , Haibo Chen

Verifying the credibility of Cyber Threat Intelligence (CTI) is essential for reliable cybersecurity defense. However, traditional approaches typically treat this task as a static classification problem, relying on handcrafted features or…

密码学与安全 · 计算机科学 2025-07-16 Fengxiao Tang , Huan Li , Ming Zhao , Zongzong Wu , Shisong Peng , Tao Yin

Precise interference detection and identification are crucial for enhancing the survivability of communication systems in non-cooperative wireless environments. While deep learning (DL) has advanced this field, existing single-task learning…

机器学习 · 计算机科学 2026-04-13 H. Xu , B. He , S. Wang

Large Language Models (LLMs) have achieved impressive performance across diverse tasks but continue to struggle with learning transitive relations, a cornerstone for complex planning. To address this issue, we investigate the Multi-Token…

人工智能 · 计算机科学 2025-09-30 Qimin Zhong , Hao Liao , Siwei Wang , Mingyang Zhou , Xiaoqun Wu , Rui Mao , Wei Chen

Motivational interviewing (MI) promotes behavioural change in substance use disorders. Its fidelity is measured using the Motivational Interviewing Treatment Integrity (MITI) framework. While large language models (LLMs) can potentially…

Click-through rate (CTR) prediction is a critical task in online advertising and recommender systems, relying on effective modeling of feature interactions. Explicit interactions capture predefined relationships, such as inner products, but…

信息检索 · 计算机科学 2025-05-27 Kefan Wang , Hao Wang , Wei Guo , Yong Liu , Jianghao Lin , Defu Lian , Enhong Chen

Accurate analysis of industrial time-series big data is critical for the Prognostics and Health Management (PHM) of industrial equipment. While recent advancements in Large Language Models (LLMs) have shown promise in time-series analysis,…

机器学习 · 计算机科学 2026-03-10 Haiteng Wang , Yikang Li , Yunfei Zhu , Jingheng Yan , Lei Ren , Laurence T. Yang

Large language models (LLMs) are effective at capturing complex, valuable conceptual representations from textual data for a wide range of real-world applications. However, in fields like Intelligent Fault Diagnosis (IFD), incorporating…

人工智能 · 计算机科学 2024-12-03 Hamzah A. A. M. Qaid , Bo Zhang , Dan Li , See-Kiong Ng , Wei Li

Despite the recent broad adoption of Large Language Models (LLMs) across various domains, their potential for enriching information systems in extracting and exploring Linked Data (LD) and Resource Description Framework (RDF) triplestores…

信息检索 · 计算机科学 2024-09-25 Omar Mussa , Omer Rana , Benoît Goossens , Pablo Orozco-Terwengel , Charith Perera

Deep reinforcement learning (DRL) shows promising potential for autonomous driving decision-making. However, DRL demands extensive computational resources to achieve a qualified policy in complex driving scenarios due to its low learning…

机器人学 · 计算机科学 2024-12-25 Hao Pang , Zhenpo Wang , Guoqiang Li

The use of large language models (LLMs) in qualitative analysis offers enhanced efficiency but raises questions about their alignment with the contextual nature of research for design (RfD). This research examines the trustworthiness of…

人机交互 · 计算机科学 2025-04-24 Joel Oksanen , Andrés Lucero , Perttu Hämäläinen

Drug combinations offer therapeutic benefits but also carry the risk of adverse drug-drug interactions (DDIs), especially under complex molecular structures. Accurate DDI event prediction requires capturing fine-grained inter-drug…

机器学习 · 计算机科学 2025-10-27 Xuan Lin , Aocheng Ding , Tengfei Ma , Hua Liang , Zhe Quan

The identification of drug-target interactions (DTI) is critical for drug discovery and repositioning, as it reveals potential therapeutic uses of existing drugs, accelerating development and reducing costs. However, most existing models…

机器学习 · 计算机科学 2025-07-22 Xiang Zhao , Ruijie Li , Qiao Ning , Shikai Guo , Hui Li , Qian Ma

Predicting group behavior, how individuals coordinate, communicate, and interact during collaborative tasks, is essential for designing systems that can support team performance through real-time prediction and realistic simulation of…

人机交互 · 计算机科学 2026-04-13 Diana Romero , Xin Gao , Daniel Khalkhali , Salma Elmalaki
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