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Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

The class distribution of data is one of the factors that regulates the performance of machine learning models. However, investigations on the impact of different distributions available in the literature are very few, sometimes absent for…

计算机视觉与模式识别 · 计算机科学 2020-12-23 Ismat Ara Reshma , Sylvain Cussat-Blanc , Radu Tudor Ionescu , Hervé Luga , Josiane Mothe

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Contrastive Self-supervised Learning (CSL) is a practical solution that learns meaningful visual representations from massive data in an unsupervised approach. The ordinary CSL embeds the features extracted from neural networks onto…

计算机视觉与模式识别 · 计算机科学 2022-08-19 Shentong Mo , Zhun Sun , Chao Li

We propose Spatial-Aware Correlated Multiple Instance Learning (SAC-MIL) for performing WSI classification. SAC-MIL consists of a positional encoding module to encode position information and a SAC block to perform full instance…

计算机视觉与模式识别 · 计算机科学 2025-09-05 Yu Bai , Zitong Yu , Haowen Tian , Xijing Wang , Shuo Yan , Lin Wang , Honglin Li , Xitong Ling , Bo Zhang , Zheng Zhang , Wufan Wang , Hui Gao , Xiangyang Gong , Wendong Wang

In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Accurate and efficient registration of whole slide images (WSIs) is essential for high-resolution, nuclei-level analysis in multi-stained tissue slides. We propose a novel coarse-to-fine framework CORE for accurate nuclei-level registration…

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Survival prediction using whole-slide images (WSIs) is crucial in cancer re-search. Despite notable success, existing approaches are limited by their reliance on sparse slide-level labels, which hinders the learning of discriminative…

计算机视觉与模式识别 · 计算机科学 2025-07-08 Jiaqi Cui , Lu Wen , Yuchen Fei , Bo Liu , Luping Zhou , Dinggang Shen , Yan Wang

Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…

图像与视频处理 · 电气工程与系统科学 2020-03-17 Qiang Li , Xianming Liu , Kaige Han , Cheng Guo , Xiangyang Ji , Xiaolin Wu

Interpretability is essential in Whole Slide Image (WSI) analysis for computational pathology, where understanding model predictions helps build trust in AI-assisted diagnostics. While Integrated Gradients (IG) and related attribution…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Anh Mai Vu , Tuan L. Vo , Ngoc Lam Quang Bui , Nam Nguyen Le Binh , Akash Awasthi , Huy Quoc Vo , Thanh-Huy Nguyen , Zhu Han , Chandra Mohan , Hien Van Nguyen

Machine learning in computational pathology (CPath) often aggregates patch-level predictions from multi-gigapixel Whole Slide Images (WSIs) to generate WSI-level prediction scores for crucial tasks such as survival prediction and drug…

机器学习 · 计算机科学 2025-12-29 Piotr Keller , Muhammad Dawood , Brinder Singh Chohan , Fayyaz ul Amir Afsar Minhas

Subspace clustering is a powerful unsupervised approach for hyperspectral image (HSI) analysis, but its high computational and memory costs limit scalability. Superpixel segmentation can improve efficiency by reducing the number of data…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Aleksandra Pizurica

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

图像与视频处理 · 电气工程与系统科学 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

The last decade has seen significant advances in computer-aided diagnostics for cytological screening, mainly through the improvement and integration of scanning techniques such as whole slide imaging (WSI) and the combination with deep…

信号处理 · 电气工程与系统科学 2026-01-23 Philip Groult , Julia D. Sistermanns , Ellen Emken , Oliver Hayden , Wolfgang Utschick

The multi-scale information among the whole slide images (WSIs) is essential for cancer diagnosis. Although the existing multi-scale vision Transformer has shown its effectiveness for learning multi-scale image representation, it still…

计算机视觉与模式识别 · 计算机科学 2023-05-26 Saisai Ding , Juncheng Li , Jun Wang , Shihui Ying , Jun Shi

How similar are two images? In computational pathology, where Whole Slide Images (WSIs) of digitally scanned tissue samples from patients can be multi-gigapixels in size, determination of degree of similarity between two WSIs is a…

图像与视频处理 · 电气工程与系统科学 2023-01-24 Piotr Keller , Muhammad Dawood , Fayyaz ul Amir Afsar Minhas

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

计算机视觉与模式识别 · 计算机科学 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi
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