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Anatomical changes during intensity-modulated proton therapy (IMPT) for head-and-neck cancer (HNC) can shift Bragg peaks, risking tumor underdosing and organ-at-risk overdosing. Treatment replanning is often required to maintain clinically…

医学物理 · 物理学 2025-08-13 Malvern Madondo , Yuan Shao , Yingzi Liu , Jun Zhou , Xiaofeng Yang , Zhen Tian

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

Mapping deep neural networks (DNNs) to hardware is critical for optimizing latency, energy consumption, and resource utilization, making it a cornerstone of high-performance accelerator design. Due to the vast and complex mapping space,…

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

定量方法 · 定量生物学 2024-09-19 Qingqing Wang , Chang Chang

Head and Neck (H\&N) organ-at-risk (OAR) and tumor segmentations are essential components of radiation therapy planning. The varying anatomic locations and dimensions of H\&N nodal Gross Tumor Volumes (GTVn) and H\&N primary gross tumor…

图像与视频处理 · 电气工程与系统科学 2022-11-01 Abhishek Srivastava , Debesh Jha , Bulent Aydogan , Mohamed E. Abazeed , Ulas Bagci

Offline multi-agent reinforcement learning (MARL) addresses key limitations of online MARL, such as safety concerns, expensive data collection, extended training intervals, and high signaling overhead caused by online interactions with the…

多智能体系统 · 计算机科学 2025-01-23 Eslam Eldeeb , Hirley Alves

Objective: Intensity-modulated radiation therapy (IMRT) beam angle optimization (BAO) is a challenging combinatorial optimization problem that is NP-hard. In this study, we aim to develop a personalized BAO algorithm for IMRT that improves…

医学物理 · 物理学 2023-03-08 Peng Bao , Gong Wang , Ruijie Yang , Bin Dong

Model-based reinforcement learning (MBRL) has been proposed as a promising alternative solution to tackle the high sampling cost challenge in the canonical reinforcement learning (RL), by leveraging a learned model to generate synthesized…

机器学习 · 计算机科学 2019-06-06 Yuanlong Li , Linsen Dong , Xin Zhou , Yonggang Wen , Kyle Guan

A comprehensive and reliable survival prediction model is of great importance to assist in the personalized management of Head and Neck Cancer (HNC) patients treated with curative Radiation Therapy (RT). In this work, we propose IMLSP, an…

计算机视觉与模式识别 · 计算机科学 2024-05-10 Meixu Chen , Kai Wang , Jing Wang

Reconfigurable manufacturing systems (RMS) are critical for future market adjustment given their rapid adaptation to fluctuations in consumer demands, the introduction of new technological advances, and disruptions in linked supply chain…

多智能体系统 · 计算机科学 2025-11-12 Manonmani Sekar , Nasim Nezamoddini

Decentralized cooperative multi-agent deep reinforcement learning (MARL) can be a versatile learning framework, particularly in scenarios where centralized training is either not possible or not practical. One of the critical challenges in…

The Intelligent Transportation System (ITS) environment is known to be dynamic and distributed, where participants (vehicle users, operators, etc.) have multiple, changing and possibly conflicting objectives. Although Reinforcement Learning…

机器学习 · 计算机科学 2024-03-19 Jing Tan , Ramin Khalili , Holger Karl

Purpose: Organ-at-risk (OAR) delineation is a key step for cone-beam CT (CBCT) based adaptive radiotherapy planning that can be a time-consuming, labor-intensive, and subject-to-variability process. We aim to develop a fully automated…

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment…

医学物理 · 物理学 2024-12-02 Sangwook Kim , Aly Khalifa , Thomas G. Purdie , Chris McIntosh

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…

The teleoperated driving (TD) scenario comes with stringent Quality of Service (QoS) communication constraints, especially in terms of end-to-end (E2E) latency and reliability. In this context, Predictive Quality of Service (PQoS), possibly…

网络与互联网体系结构 · 计算机科学 2025-05-07 Giacomo Avanzi , Marco Giordani , Michele Zorzi

Purpose: This study aimed to use deep learning-based dose prediction to assess head and neck (HN) plan quality and identify suboptimal plans. Methods: A total of 245 VMAT HN plans were created using RapidPlan knowledge-based planning (KBP).…

Background: Real-time treatment planning in IMRT is challenging due to complex beam interactions. AI has improved automation, but existing models require large, high-quality datasets and lack universal applicability. Deep reinforcement…

医学物理 · 物理学 2025-02-26 Md Mainul Abrar , Parvat Sapkota , Damon Sprouts , Xun Jia , Yujie Chi

Over half a million individuals are diagnosed with head and neck cancer each year worldwide. Radiotherapy is an important curative treatment for this disease, but it requires manual time consuming delineation of radio-sensitive organs at…

Intraday surgical scheduling is a multi-objective decision problem under uncertainty-balancing elective throughput, urgent and emergency demand, delays, sequence-dependent setups, and overtime. We formulate the problem as a cooperative…

机器学习 · 计算机科学 2025-12-05 Kailiang Liu , Ying Chen , Ralf Borndörfer , Thorsten Koch
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