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Disentangled representation learning aims to capture the underlying explanatory factors of observed data, enabling a principled understanding of the data-generating process. Recent advances in generative modeling have introduced new…

机器学习 · 计算机科学 2026-05-12 Jinjin Chi , Taoping Liu , Mengtao Yin , Ximing Li , Yongcheng Jing , Jialie Shen , Leszek Rutkowski , Dacheng Tao

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang

Multiple Instance Learning (MIL) has been widely applied in pathology towards solving critical problems such as automating cancer diagnosis and grading, predicting patient prognosis, and therapy response. Deploying these models in a…

计算机视觉与模式识别 · 计算机科学 2022-10-18 Syed Ashar Javed , Dinkar Juyal , Harshith Padigela , Amaro Taylor-Weiner , Limin Yu , Aaditya Prakash

Neural networks exhibit severe brittleness to semantically irrelevant transformations. A mere 75ms electrocardiogram (ECG) phase shift degrades latent cosine similarity from 1.0 to 0.2, while sensor rotations collapse activity recognition…

机器学习 · 计算机科学 2025-11-20 Zhengyang Shen , Hua Tu , Mayue Shi

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

图像与视频处理 · 电气工程与系统科学 2022-02-14 Weizhen Liu , Qian He , Xuming He

Disentangled representation learning finds compact, independent and easy-to-interpret factors of the data. Learning such has been shown to require an inductive bias, which we explicitly encode in a generative model of images. Specifically,…

计算机视觉与模式识别 · 计算机科学 2019-11-14 Nicki Skafte Detlefsen , Søren Hauberg

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Weakly supervised instance segmentation (WSIS) using only image-level labels is a challenging task due to the difficulty of aligning coarse annotations with the finer task. However, with the advancement of deep neural networks (DNNs), WSIS…

计算机视觉与模式识别 · 计算机科学 2024-02-13 Zecheng Li , Zening Zeng , Yuqi Liang , Jin-Gang Yu

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Understanding the decisions made by deep neural networks is essential in high-stakes domains such as medical imaging and autonomous driving. Yet, these models often lack transparency, particularly in computer vision.…

计算机视觉与模式识别 · 计算机科学 2025-07-28 Viktar Dubovik , Łukasz Struski , Jacek Tabor , Dawid Rymarczyk

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

计算机视觉与模式识别 · 计算机科学 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

Multiple Instance Learning (MIL) gains popularity in many real-life machine learning applications due to its weakly supervised nature. However, the corresponding effort on explaining MIL lags behind, and it is usually limited to presenting…

Whole Slide Image (WSI) analysis, with its ability to reveal detailed tissue structures in magnified views, plays a crucial role in cancer diagnosis and prognosis. Due to their giga-sized nature, WSIs require substantial storage and…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Doanh Cao Bui , Jin Tae Kwak

Multi-modal MRIs are widely used in neuroimaging applications since different MR sequences provide complementary information about brain structures. Recent works have suggested that multi-modal deep learning analysis can benefit from…

计算机视觉与模式识别 · 计算机科学 2021-06-14 Jiahong Ouyang , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao , Greg Zaharchuk

Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL). However, the slide representations resulting from this approach are highly tailored to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Andrew H. Song , Richard J. Chen , Tong Ding , Drew F. K. Williamson , Guillaume Jaume , Faisal Mahmood

Tensor-based multi-view clustering has recently received significant attention due to its exceptional ability to explore cross-view high-order correlations. However, most existing methods still encounter some limitations. (1) Most of them…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Deng Xu , Chao Zhang , Zechao Li , Chunlin Chen , Huaxiong Li

Although disentangled representations are often said to be beneficial for downstream tasks, current empirical and theoretical understanding is limited. In this work, we provide evidence that disentangled representations coupled with sparse…

Generative models that learn disentangled representations for different factors of variation in an image can be very useful for targeted data augmentation. By sampling from the disentangled latent subspace of interest, we can efficiently…

计算机视觉与模式识别 · 计算机科学 2018-05-08 Ananya Harsh Jha , Saket Anand , Maneesh Singh , V. S. R. Veeravasarapu

By highlighting the regions of the input image that contribute the most to the decision, saliency maps have become a popular method to make neural networks interpretable. In medical imaging, they are particularly well-suited to explain…

计算机视觉与模式识别 · 计算机科学 2023-01-06 Kaifeng Zou , Sylvain Faisan , Fabrice Heitz , Marie Epain , Pierre Croisille , Laurent Fanton , Sébastien Valette

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold
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