相关论文: Knowledge Elicitation with Large Language Models f…

Cancer stage classification is important for making treatment and care management plans for oncology patients. Information on staging is often included in unstructured form in clinical, pathology, radiology and other free-text reports in…

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by…

Large Language Models (LLMs) have shown unprecedented performance in various real-world applications. However, they are known to generate factually inaccurate outputs, a.k.a. the hallucination problem. In recent years, incorporating…

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Extracting MITRE ATT\&CK Tactics, Techniques, and Procedures (TTPs) from natural language threat reports is crucial yet challenging. Existing methods primarily focus on performance metrics using data-driven approaches, often neglecting…

Current multimodal survival prediction methods typically rely on pathology images (WSIs) and genomic data, both of which are high-dimensional and redundant, making it difficult to extract discriminative features from them and align…

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

The automatic construction of knowledge graphs (KGs) is an important research area in medicine, with far-reaching applications spanning drug discovery and clinical trial design. These applications hinge on the accurate identification of…

The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized…

Large Language Models (LLMs) have shown significant promise across various natural language processing tasks. However, their application in the field of pathology, particularly for extracting meaningful insights from unstructured medical…

Although achieving great success, Large Language Models (LLMs) usually suffer from unreliable hallucinations. Although language attribution can be a potential solution, there are no suitable benchmarks and evaluation metrics to attribute…

Knowledge tagging for questions plays a crucial role in contemporary intelligent educational applications, including learning progress diagnosis, practice question recommendations, and course content organization. Traditionally, these…

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

While the next-token prediction (NTP) paradigm enables large language models (LLMs) to express their intrinsic knowledge, its sequential nature constrains performance on specialized, non-generative tasks. We attribute this performance…

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Efficient knowledge management plays a pivotal role in augmenting both the operational efficiency and the innovative capacity of businesses and organizations. By indexing knowledge through vectorization, a variety of knowledge retrieval…