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Cutting edge techniques developed in the general NLP domain are often subsequently applied to the high-value, data-rich biomedical domain. The past few years have seen generative language models (LMs), instruction finetuning, and few-shot…

计算与语言 · 计算机科学 2025-07-28 Aviv Brokman , Ramakanth Kavuluru

Aligning Large Language Models (LLMs) with high-stakes medical standards remains a significant challenge, primarily due to the dissonance between coarse-grained preference signals and the complex, multi-dimensional nature of clinical…

人工智能 · 计算机科学 2026-04-10 He Geng , Yangmin Huang , Lixian Lai , Qianyun Du , Hui Chu , Zhiyang He , Jiaxue Hu , Xiaodong Tao

Large Language Models (LLMs) have propelled groundbreaking advancements across several domains and are commonly used for text generation applications. However, the computational demands of these complex models pose significant challenges,…

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

计算与语言 · 计算机科学 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Recent advances in reasoning with large language models (LLMs) have demonstrated strong performance on complex mathematical tasks, including combinatorial optimization. Techniques such as Chain-of-Thought and In-Context Learning have…

人工智能 · 计算机科学 2025-09-17 Marylou Fauchard , Florian Carichon , Margarida Carvalho , Golnoosh Farnadi

Large language models (LLMs) have achieved impressive performance, leading to their widespread adoption as decision-support tools in resource-constrained contexts like hiring and admissions. There is, however, scientific consensus that AI…

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

计算与语言 · 计算机科学 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

Pre-trained language models (PLMs) have proven to be effective for document re-ranking task. However, they lack the ability to fully interpret the semantics of biomedical and health-care queries and often rely on simplistic patterns for…

计算与语言 · 计算机科学 2023-05-09 Deepak Gupta , Dina Demner-Fushman

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

计算与语言 · 计算机科学 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Large Language Models (LLMs) and causal learning each hold strong potential for clinical decision making (CDM). However, their synergy remains poorly understood, largely due to the lack of systematic benchmarks evaluating their integration…

机器学习 · 计算机科学 2025-11-14 Linna Wang , Zhixuan You , Qihui Zhang , Jiunan Wen , Ji Shi , Yimin Chen , Yusen Wang , Fanqi Ding , Ziliang Feng , Li Lu

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

计算与语言 · 计算机科学 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Accurate recognition of biomedical named entities is critical for medical information extraction and knowledge discovery. However, existing methods often struggle with nested entities, entity boundary ambiguity, and cross-lingual…

计算与语言 · 计算机科学 2025-10-13 Tengxiao Lv , Ling Luo , Juntao Li , Yanhua Wang , Yuchen Pan , Chao Liu , Yanan Wang , Yan Jiang , Huiyi Lv , Yuanyuan Sun , Jian Wang , Hongfei Lin

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

计算与语言 · 计算机科学 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large Language Models (LLMs) have demonstrated impressive performance in biomedical relation extraction, even in zero-shot scenarios. However, evaluating LLMs in this task remains challenging due to their ability to generate human-like…

计算与语言 · 计算机科学 2025-06-03 Md Tahmid Rahman Laskar , Israt Jahan , Elham Dolatabadi , Chun Peng , Enamul Hoque , Jimmy Huang

Pre-trained language models have attracted increasing attention in the biomedical domain, inspired by their great success in the general natural language domain. Among the two main branches of pre-trained language models in the general…

计算与语言 · 计算机科学 2023-04-04 Renqian Luo , Liai Sun , Yingce Xia , Tao Qin , Sheng Zhang , Hoifung Poon , Tie-Yan Liu

Pretraining large neural language models, such as BERT, has led to impressive gains on many natural language processing (NLP) tasks. However, most pretraining efforts focus on general domain corpora, such as newswire and Web. A prevailing…

计算与语言 · 计算机科学 2021-09-20 Yu Gu , Robert Tinn , Hao Cheng , Michael Lucas , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Linking biomedical entities is an essential aspect in biomedical natural language processing tasks, such as text mining and question answering. However, a difficulty of linking the biomedical entities using current large language models…

计算与语言 · 计算机科学 2023-08-29 Xi Yan , Cedric Möller , Ricardo Usbeck

Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

计算与语言 · 计算机科学 2025-02-06 Seonok Kim

Large language models are often assumed to acquire increasingly structured, generalizable internal representations simply by scaling data and parameters. We interrogate this assumption by introducing a Clinical Trial Natural Language…

人工智能 · 计算机科学 2025-08-15 Maël Jullien , Marco Valentino , André Freitas