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The paper introduces a framework for the evaluation of the encoding of factual scientific knowledge, designed to streamline the manual evaluation process typically conducted by domain experts. Inferring over and extracting information from…

计算与语言 · 计算机科学 2024-10-21 Magdalena Wysocka , Oskar Wysocki , Maxime Delmas , Vincent Mutel , Andre Freitas

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

计算与语言 · 计算机科学 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

人机交互 · 计算机科学 2025-03-03 Siting Liang , Daniel Sonntag

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

计算与语言 · 计算机科学 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

While large language models (LLMs) perform strongly on diverse tasks, their trustworthiness is limited by erratic behavior that is unfaithful to their internal knowledge. In particular, LLMs often fail on multiple-choice questions (MCQs)…

计算与语言 · 计算机科学 2026-02-05 Yoonah Park , Haesung Pyun , Yohan Jo

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

The evaluation of large language models (LLMs) relies heavily on standardized benchmarks. These benchmarks provide useful aggregated metrics for a given capability, but those aggregated metrics can obscure (i) particular sub-areas where the…

计算与语言 · 计算机科学 2025-12-25 Matyas Bohacek , Nino Scherrer , Nicholas Dufour , Thomas Leung , Christoph Bregler , Stephanie C. Y. Chan

We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…

机器学习 · 计算机科学 2026-02-24 Razvan Marinescu , Victoria-Elisabeth Gruber , Diego Fajardo

Due to the implement of guardrails by developers, Large language models (LLMs) have demonstrated exceptional performance in explicit bias tests. However, bias in LLMs may occur not only explicitly, but also implicitly, much like humans who…

计算与语言 · 计算机科学 2025-03-05 Xinru Lin , Luyang Li

Large Language Models (LLMs) are being adopted across a wide range of tasks, including decision-making processes in industries where bias in AI systems is a significant concern. Recent research indicates that LLMs can harbor implicit biases…

计算与语言 · 计算机科学 2024-10-18 Divyanshu Kumar , Umang Jain , Sahil Agarwal , Prashanth Harshangi

Large Language Models (LLMs) are versatile and demonstrate impressive generalization ability by mining and learning information from extensive unlabeled text. However, they still exhibit reasoning mistakes, often stemming from knowledge…

计算与语言 · 计算机科学 2024-08-22 Kai Xiong , Xiao Ding , Li Du , Jiahao Ying , Ting Liu , Bing Qin , Yixin Cao

The scientific literature's exponential growth makes it increasingly challenging to navigate and synthesize knowledge across disciplines. Large language models (LLMs) are powerful tools for understanding scientific text, but they fail to…

计算与语言 · 计算机科学 2025-05-30 Abhipsha Das , Nicholas Lourie , Siavash Golkar , Mariel Pettee

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

计算与语言 · 计算机科学 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

机器学习 · 计算机科学 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Introduction. Advances in large language models (LLMs) offer a chance to act as scientific assistants, helping people grasp complex research areas. This study examines how LLMs evolve in healthcare disparities research, with attention to…

计算机与社会 · 计算机科学 2025-12-10 David An

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

计算与语言 · 计算机科学 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and…

This work presents a framework for assessing whether large language models (LLMs) encode more factual knowledge in their parameters than what they express in their outputs. While a few studies hint at this possibility, none has clearly…

计算与语言 · 计算机科学 2025-08-07 Zorik Gekhman , Eyal Ben David , Hadas Orgad , Eran Ofek , Yonatan Belinkov , Idan Szpektor , Jonathan Herzig , Roi Reichart

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

人工智能 · 计算机科学 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen
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