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Machine learning models that aim to predict dementia onset usually follow the classification methodology ignoring the time until an event happens. This study presents an alternative, using survival analysis within the context of machine…

机器学习 · 计算机科学 2023-06-21 Daniel Stamate , Henry Musto , Olesya Ajnakina , Daniel Stahl

Background and Objective: Colorectal cancer is a high mortality cancer. Clinical data analysis plays a crucial role in predicting the survival of colorectal cancer patients, enabling clinicians to make informed treatment decisions. However,…

机器学习 · 计算机科学 2023-09-06 Sadegh Soleimani , Mahsa Bahrami , Mansour Vali

The introduction of machine learning (ML) techniques to the field of survival analysis has increased the flexibility of modeling approaches, and ML based models have become state-of-the-art. These models optimize their own cost functions,…

机器学习 · 统计学 2023-02-24 Alex Nowak-Vila , Kevin Elgui , Genevieve Robin

Gliomas are lethal type of central nervous system tumors with a poor prognosis. Recently, with the advancements in the micro-array technologies thousands of gene expression related data of glioma patients are acquired, leading for salient…

基因组学 · 定量生物学 2020-11-03 Navodini Wijethilake , Dulani Meedeniya , Charith Chitraranjan , Indika Perera

Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals…

机器学习 · 计算机科学 2025-01-23 Yonghao Zhao , Changtao Li , Chi Shu , Qingbin Wu , Hong Li , Chuan Xu , Tianrui Li , Ziqiang Wang , Zhipeng Luo , Yazhou He

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

机器学习 · 计算机科学 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Survival time prediction from medical images is important for treatment planning, where accurate estimations can improve healthcare quality. One issue affecting the training of survival models is censored data. Most of the current survival…

计算机视觉与模式识别 · 计算机科学 2022-05-27 Renato Hermoza , Gabriel Maicas , Jacinto C. Nascimento , Gustavo Carneiro

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

机器学习 · 计算机科学 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Traditional survival analysis methods often struggle with complex time-dependent data,failing to capture and interpret dynamic characteristics adequately.This study aims to evaluate the performance of three long-sequence…

机器学习 · 计算机科学 2024-07-22 Runquan Zhang , Jiawen Jiang , Xiaoping Shi

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

计算与语言 · 计算机科学 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Head and Neck Squamous Cell Carcinoma (HNSCC) is one of cancer type that is most distressing leading to acute pain, effecting speech and primary survival functions such as swallowing and breathing. The morbidity and mortality of HNSCC…

基因组学 · 定量生物学 2021-05-18 Saurav Mandal , Akshansh Gupta , Waribam Pratibha Chanu

Breast cancer (BC) remains a significant global health challenge, with personalized treatment selection complicated by the disease's molecular and clinical heterogeneity. BC treatment decisions rely on various patient-specific clinical…

应用统计 · 统计学 2025-07-10 Md Nahid Hasan , Md Monzur Murshed , Md Mahadi Hasan , Faysal A. Chowdhury

Objective: Survival analysis is central to medical prediction, yet large language models (LLMs) are rarely used as end-to-end survival models because censoring prevents straightforward supervised fine-tuning. Here we present LLMSurvival, a…

人工智能 · 计算机科学 2026-05-26 Yishu Wei , Hexin Dong , Yi Lin , Jiahe Qian , Yi Liu , Yifan Peng

Lung cancer is a significant cause of mortality worldwide, emphasizing the importance of early detection for improved survival rates. In this study, we propose a machine learning (ML) tool trained on data from the PLCO Cancer Screening…

机器学习 · 计算机科学 2023-08-24 Pierre-Louis Benveniste , Julie Alberge , Lei Xing , Jean-Emmanuel Bibault

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

Multimodal deep learning models that fuse whole-slide histopathology images with genomic data have achieved strong discriminative performance for cancer survival prediction, as measured by the concordance index. Yet whether the survival…

机器学习 · 计算机科学 2026-04-07 Sajad Ghawami

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

计算机视觉与模式识别 · 计算机科学 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

机器学习 · 计算机科学 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Accurate survival prediction in oncology requires integrating diverse imaging modalities to capture the complex interplay of tumor biology. Traditional single-modality approaches often fail to leverage the complementary insights provided by…

计算机视觉与模式识别 · 计算机科学 2025-03-14 Ho Hin Lee , Alberto Santamaria-Pang , Jameson Merkov , Matthew Lungren , Ivan Tarapov

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…