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Label-free and nondestructive mid-infrared vibrational hyperspectral imaging is emerging as an important ex-vivo tissue analysis tool, providing spatially resolved biochemical information critical to understanding physiological and…

光学 · 物理学 2023-04-28 S. Rosas , K. A. Schoeller , E. Chang , H. Mei , M. A. Kats , K. W. Eliceiri , X. Zhao , F. Yesilkoy

Mid-infrared spectroscopy offers powerful label-free molecular analysis capabilities but faces significant challenges when analyzing complex biological samples. Here, we present a transformative surface-enhanced infrared absorption…

Hyperspectral microscopy is an imaging technique that provides spectroscopic information with high spatial resolution. When applied in the relevant wavelength region, such as in the infrared (IR), it can reveal a rich spectral fingerprint…

Numerous molecules exhibit unique absorption bands in the fingerprint infrared (IR) region, allowing chemical identification and detection. This makes IR spectroscopy an essential tool in biomedical diagnostics, sensing, and material…

光学 · 物理学 2022-02-04 Anna V. Paterova , Zi S. D. Toa , Hongzhi Yang , Leonid A. Krivitsky

Sensing with undetected photons has become a vibrant, application-driven research domain with a special focus on the mid-infrared (mid-IR) wavelength region. Since the mid-IR contains spectral bands with highly specific and strong molecular…

Mid-infrared spectroscopy enables biochemical sensing by identifying vibrational molecular fingerprints, but it faces limitations in instrumentation portability and analytical sensitivity. Optical metasurfaces with strong mid-IR photonic…

Mid-infrared (mid-IR) spectroscopy offers unparalleled opportunities in sensing through chemically specific detection of molecular absorption fingerprints. Yet, its practical applications are limited by the weak light-matter interaction in…

We discuss the Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - InfraRed (FTIR) spectrometry. We explore the potential of the infrared surface plasmon resonance technique for biological studies in aqueous solutions…

生物物理 · 物理学 2010-02-03 M. Golosovsky , V. Lirtsman , V. Yashunsky , D. Davidov , B. Aroeti

We report on a Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - Infra - Red (FTIR) spectrometer. In contrast to the conventional surface plasmon technique, operating at a fixed wavelength and a variable angle of…

软凝聚态物质 · 物理学 2013-03-19 V. Lirtsman , M. Golosovsky , D. Davidov

Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical…

The optical elements comprised of sub-diffractive light scatterers, or metasurfaces, hold a promise to reduce the footprint and unfold new functionalities of optical devices. A particular interest is focused on metasurfaces for manipulation…

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

光学 · 物理学 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

The study is devoted to development and optimization of a metasurface-based sensor with graphene constituents for potential biosensing applications. A unit cell of the proposed metasurface consists of a thin flexible dielectric substrate…

光学 · 物理学 2026-01-12 K. S. Kuznetsova , V. A. Pashynska , Z. E. Eremenko

Plasmonic sensing in the infrared region employs the direct interaction of the vibrational fingerprints of molecules with the plasmonic resonances, creating surface-enhanced sensing platforms that are superior than the traditional…

Spectral measurements in the infrared (IR) optical range provide unique fingerprints of materials which are useful for material analysis, environmental sensing, and health diagnostics. Current IR spectroscopy techniques require the use of…

量子物理 · 物理学 2016-02-05 Dmitry A. Kalashnikov , Anna V. Paterova , Sergei P. Kulik , Leonid A. Krivitsky

Magnetic resonance imaging (MRI) is the cornerstone technique for diagnostic medicine, biology, and neuroscience. This imaging method is highly innovative, noninvasive and its impact continues to grow. It can be used for measuring changes…

Strain-level identification of viruses is critical for effective public health responses to potential outbreaks, yet current diagnostic methods often lack the necessary speed or sensitivity. Surface-enhanced Raman spectroscopy (SERS) offers…

In Internet of Things, where billions of devices with limited resources are communicating with each other, security has become a major stumbling block affecting the progress of this technology. Existing authentication schemes-based on…

信号处理 · 电气工程与系统科学 2020-12-08 Sekhar Rajendran , Zhi Sun , Feng Lin , Kui Ren

Fourier transform infrared (FTIR) spectrometers have been the dominant technology in the field of mid-infrared (MIR)spectroscopy for decades. Supercontinuum laser sources operating in the MIR spectral region now offer the potential to…

仪器与探测器 · 物理学 2020-04-17 Ivan Zorin , Jakob Kilgus , Kristina Duswald , Bernhard Lendl , Bettina Heise , Markus Brandstetter
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