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We present significant extensions to diffusion-based sequence generation models, blurring the line with autoregressive language models. We introduce hyperschedules, which assign distinct noise schedules to individual token positions,…

机器学习 · 计算机科学 2025-10-08 Nima Fathi , Torsten Scholak , Pierre-André Noël

Language models have advanced sequence analysis, yet DNA foundation models often lag behind task-specific methods for unclear reasons. We present AntigenLM, a generative DNA language model pretrained on influenza genomes with intact,…

基因组学 · 定量生物学 2026-02-12 Yue Pei , Xuebin Chi , Yu Kang

Following its success for vision and text, the "foundation model" (FM) paradigm -- pretraining large models on massive data, then fine-tuning on target tasks -- has rapidly expanded to domains in the sciences, engineering, healthcare, and…

机器学习 · 计算机科学 2025-03-24 Zongzhe Xu , Ritvik Gupta , Wenduo Cheng , Alexander Shen , Junhong Shen , Ameet Talwalkar , Mikhail Khodak

Meaning Representations (AMRs) are broad-coverage sentence-level semantic graphs. Existing approaches to generating text from AMR have focused on training sequence-to-sequence or graph-to-sequence models on AMR annotated data only. In this…

Symbolic regression algorithms search a space of mathematical expressions for formulas that explain given data. Transformer-based models have emerged as a promising, scalable approach shifting the expensive combinatorial search to a…

机器学习 · 计算机科学 2025-09-25 Henrik Voigt , Paul Kahlmeyer , Kai Lawonn , Michael Habeck , Joachim Giesen

Foundation models (FMs) trained on electronic health records (EHRs) have shown strong performance on a range of clinical prediction tasks. However, adapting these models to local health systems remains challenging due to limited data…

Over the last two decades, language modeling has experienced a shift from the use of predominantly recurrent architectures that process tokens sequentially during training and inference to non-recurrent models that process sequence elements…

计算与语言 · 计算机科学 2026-05-20 Benjamin L. Badger

Mobility datasets are fundamental for evaluating algorithms pertaining to geographic information systems and facilitating experimental reproducibility. But privacy implications restrict sharing such datasets, as even aggregated…

机器学习 · 计算机科学 2018-12-03 Vaibhav Kulkarni , Natasa Tagasovska , Thibault Vatter , Benoit Garbinato

With the advent of powerful neural language models over the last few years, research attention has increasingly focused on what aspects of language they represent that make them so successful. Several testing methodologies have been…

计算与语言 · 计算机科学 2023-05-26 Jordan Kodner , Nitish Gupta

Transformers have become the dominant architecture for sequence modeling by using self-attention to enable expressive and highly parallel processing. However, the resulting quadratic time and memory costs limit efficiency in long-context…

机器学习 · 计算机科学 2026-05-19 Tristan Gaudreault , Yongyi Mao

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Databases in domains such as healthcare are routinely released to the public in aggregated form. Unfortunately, naive modeling with aggregated data may significantly diminish the accuracy of inferences at the individual level. This paper…

机器学习 · 统计学 2016-05-17 Avradeep Bhowmik , Joydeep Ghosh , Oluwasanmi Koyejo

Foundation models encompass an extensive knowledge base and offer remarkable transferability. However, this knowledge becomes outdated or insufficient over time. The challenge lies in continuously updating foundation models to accommodate…

计算机视觉与模式识别 · 计算机科学 2024-04-22 Wenxuan Zhang , Paul Janson , Rahaf Aljundi , Mohamed Elhoseiny

We study the invariance characteristics of pre-trained predictive models by empirically learning transformations on the input that leave the prediction function approximately unchanged. To learn invariant transformations, we minimize the…

机器学习 · 计算机科学 2020-03-04 Mohammad Taha Bahadori , Layne C. Price

Pretraining has proven to be a powerful technique in natural language processing (NLP), exhibiting remarkable success in various NLP downstream tasks. However, in the medical domain, existing pretrained models on electronic health records…

人工智能 · 计算机科学 2023-10-23 Xiaochen Wang , Junyu Luo , Jiaqi Wang , Ziyi Yin , Suhan Cui , Yuan Zhong , Yaqing Wang , Fenglong Ma

Recent advances in autoregressive neural surrogate models have enabled orders-of-magnitude speedups in simulating dynamical systems. However, autoregressive models are generally prone to distribution drift: compounding errors in…

机器学习 · 计算机科学 2026-03-19 Qi Liu , Laure Zanna , Joan Bruna

Test-time augmentation, such as Retrieval-Augmented Generation (RAG) or tool use, critically depends on an interplay between a model's parametric knowledge and externally retrieved information. However, the theoretical underpinnings of this…

机器学习 · 计算机科学 2026-05-19 Avrim Blum , Daniel Hsu , Cyrus Rashtchian , Donya Saless

Recurrent neural networks can learn to predict upcoming words remarkably well on average; in syntactically complex contexts, however, they often assign unexpectedly high probabilities to ungrammatical words. We investigate to what extent…

计算与语言 · 计算机科学 2019-09-04 Marten van Schijndel , Aaron Mueller , Tal Linzen

Large language and music models are increasingly used for constrained generation: rhyming lines, fixed meter, inpainting or infilling, positional endings, and other global form requirements. These systems often perform strikingly well, but…

人工智能 · 计算机科学 2026-04-10 Francois Pachet , Pierre Roy

Autoregressive (AR) models have been the dominating approach to conditional sequence generation, but are suffering from the issue of high inference latency. Non-autoregressive (NAR) models have been recently proposed to reduce the latency…

机器学习 · 计算机科学 2020-07-01 Zhiqing Sun , Yiming Yang