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Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Histopathological images of tumors contain abundant information about how tumors grow and how they interact with their micro-environment. Better understanding of tissue phenotypes in these images could reveal novel determinants of…

图像与视频处理 · 电气工程与系统科学 2021-04-14 Adalberto Claudio Quiros , Roderick Murray-Smith , Ke Yuan

Deep neural networks face numerous challenges in hyperspectral image classification, including high-dimensional data, sparse ground object distributions, and spectral redundancy, which often lead to classification overfitting and limited…

计算机视觉与模式识别 · 计算机科学 2025-04-16 Guandong Li , Mengxia Ye

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies. Even though the amount of data measured for cancer patients has increased over the last years, most…

机器学习 · 统计学 2017-09-18 Nora K. Speicher , Nico Pfeifer

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Tumor-immune interactions are central to cancer progression and treatment outcomes. In this study, we present a stochastic agent-based model that integrates cellular heterogeneity, spatial cell-cell interactions, and drug resistance…

组织与器官 · 定量生物学 2026-05-19 Yuhong Zhang , Chenghang Li , Boya Wang , Jinzhi Lei

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

计算机视觉与模式识别 · 计算机科学 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

Despite tremendous progress in computer vision, there has not been an attempt for machine learning on very large-scale medical image databases. We present an interleaved text/image deep learning system to extract and mine the semantic…

计算机视觉与模式识别 · 计算机科学 2015-05-05 Hoo-Chang Shin , Le Lu , Lauren Kim , Ari Seff , Jianhua Yao , Ronald M. Summers

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

计算机视觉与模式识别 · 计算机科学 2025-01-28 Mirza Ahsan Ullah , Tehseen Zia

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

计算机视觉与模式识别 · 计算机科学 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

计算机视觉与模式识别 · 计算机科学 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

图像与视频处理 · 电气工程与系统科学 2022-02-14 Weizhen Liu , Qian He , Xuming He

Automatic melanoma segmentation in dermoscopic images is essential in computer-aided diagnosis of skin cancer. Existing methods may suffer from the hole and shrink problems with limited segmentation performance. To tackle these issues, we…

计算机视觉与模式识别 · 计算机科学 2020-01-14 Xiaoqing Guo , Zhen Chen , Yixuan Yuan

Quantifiable image patterns associated with disease progression and treatment response are critical tools for guiding individual treatment, and for developing novel therapies. Here, we show that unsupervised machine learning can identify a…

图像与视频处理 · 电气工程与系统科学 2025-07-17 Matthias Perkonigg , Nina Bastati , Ahmed Ba-Ssalamah , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Xiaofei Zhou , Michael Trauner , Georg Langs

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

计算机视觉与模式识别 · 计算机科学 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Multi-modal 3D medical image segmentation aims to accurately identify tumor regions across different modalities, facing challenges from variations in image intensity and tumor morphology. Traditional convolutional neural network (CNN)-based…

计算机视觉与模式识别 · 计算机科学 2025-05-01 Zexin Ji , Beiji Zou , Xiaoyan Kui , Hua Li , Pierre Vera , Su Ruan

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

We introduce a new neural architecture and an unsupervised algorithm for learning invariant representations from temporal sequence of images. The system uses two groups of complex cells whose outputs are combined multiplicatively: one that…

神经与进化计算 · 计算机科学 2010-06-03 Karo Gregor , Yann LeCun