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Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…

医学物理 · 物理学 2025-08-22 Erik Engwall , Victor Mikhalev , Johan Sundström , Otte Marthin , Viktor Wase

Metastasis is the process by which cells from a primary tumor disperse and form new tumors at distant anatomical locations. The treatment and prevention of metastatic cancer remains an extremely challenging problem. This work introduces a…

组织与器官 · 定量生物学 2015-11-18 Hamidreza Badri , Jagdish Ramakrishnan , Kevin Leder

We revisit the design choices in Transformers, and propose methods to address their weaknesses in handling long sequences. First, we propose a simple layer named gated attention unit, which allows the use of a weaker single-head attention…

机器学习 · 计算机科学 2022-06-28 Weizhe Hua , Zihang Dai , Hanxiao Liu , Quoc V. Le

This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…

Breast cancer is a significant public health concern and early detection is critical for triaging high risk patients. Sequential screening mammograms can provide important spatiotemporal information about changes in breast tissue over time.…

图像与视频处理 · 电气工程与系统科学 2023-06-05 Hong Hui Yeoh , Andrea Liew , Raphaël Phan , Fredrik Strand , Kartini Rahmat , Tuong Linh Nguyen , John L. Hopper , Maxine Tan

Adapting models pre-trained on large-scale datasets is a proven way to reach strong performance quickly for down-stream tasks. However, the growth of state-of-the-art mod-els makes traditional full fine-tuning unsuitable and difficult,…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Maxime Fontana , Michael Spratling , Miaojing Shi

We present a proof of concept for screening breast cancer risk by detecting biochemical alterations in breast tissue using a noninvasive and low-cost technique that uses dynamic light scattering for field effect detection by spectral…

医学物理 · 物理学 2026-04-07 Janeth Fernández-Pinto , Álvaro Gómez-Torrado , David A. Miranda

Purpose To alleviate the spatial encoding limitations of single-shot EPI by developing multi-shot segmented EPI for ultra-high-resolution fMRI with reduced ghosting artifacts from subject motion and respiration. Methods Segmented EPI can…

Objective: Radiolytic oxygen depletion (ROD) may play a role in the sparing of cells irradiated with ultra-high dose rates. Different methods have been used to quantify the effect of ROD during FLASH irradiation on cell survival, typically…

医学物理 · 物理学 2026-02-25 Juan Pardo-Montero , Isabel González-Crespo

Experimental characterization of blood flow in living organisms is crucial for understanding the development and function of cardiovascular systems, but there have been no techniques reported for snapshot imaging of thick samples in large…

In February this year Google proposed a new Transformer variant called FLASH, which has a faster speed, lower VRAM footprint and better performance. This is achieved by designing a performant layer named GAU (Gated Attention Unit), which…

计算与语言 · 计算机科学 2022-05-19 Zhenjie Liu

FLASH is the first soft X-ray FEL user facility, routinely providing brilliant photon beams for users since 2005. The second undulator branch of this facility, FLASH2, is gap-tunable which allows to test and use advanced lasing concepts. In…

Purpose: Analysis of [18F]-Fluorodeoxyglucose (FDG) kinetics in cancer has been most often limited to the evaluation of the average uptake over relatively large volumes. Nevertheless, tumor lesion almost contains inflammatory infiltrates…

Grating interferometry is a promising diagnostic technique that enables simultaneous acquisition of three complementary, synergistic X-ray images: transmission, differential phase, and dark-field. Its key advantage over other setups is its…

We present FlashSLAM, a novel SLAM approach that leverages 3D Gaussian Splatting for efficient and robust 3D scene reconstruction. Existing 3DGS-based SLAM methods often fall short in sparse view settings and during large camera movements…

计算机视觉与模式识别 · 计算机科学 2024-12-03 Phu Pham , Damon Conover , Aniket Bera

A spring-dashpot system based on the Voigt model was developed to model the correlation between abdominal respiratory motion and tumor motion during lung radiotherapy. The model was applied to clinical data comprising 52 treatment beams…

医学物理 · 物理学 2020-06-05 E. J. Ackerley , A. E. Cavan , P. L. Wilson , R. I. Berbeco , J. Meyer

T2-weighted fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) scans are important for diagnosis, treatment planning and monitoring of brain tumors. Depending on the brain tumor type, the FLAIR hyperintensity…

Purpose: To develop a novel aperture-based algorithm for volumetric modulated arc therapy (VMAT) treatment plan optimization with high quality and high efficiency. Methods: The VMAT optimization problem is formulated as a large-scale convex…

医学物理 · 物理学 2015-05-19 Chunhua Men , H. Edwin Romeijn , Xun Jia , Steve B. Jiang

The Perception-Distortion tradeoff (PD-tradeoff) theory suggests that face restoration algorithms must balance perceptual quality and fidelity. To achieve minimal distortion while maintaining perfect perceptual quality, Posterior-Mean…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Xin Luo , Menglin Zhang , Yunwei Lan , Tianyu Zhang , Rui Li , Chang Liu , Dong Liu

Background: In vivo dosimetry is essential for treatment verification in modern radiotherapy, but existing techniques are limited by spatiotemporal resolution and performance on non-uniform anatomy. Scintillation imaging dosimetry shows…

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