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Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

机器学习 · 计算机科学 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the…

机器学习 · 计算机科学 2019-06-11 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

机器学习 · 计算机科学 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

计算机视觉与模式识别 · 计算机科学 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

机器学习 · 计算机科学 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

Appropriate medication dosages in the intensive care unit (ICU) are critical for patient survival. Heparin, used to treat thrombosis and inhibit blood clotting in the ICU, requires careful administration due to its complexity and…

机器学习 · 计算机科学 2025-12-09 Yooseok Lim , Inbeom Park , Sujee Lee

Background and Objectives: We aim to establish deep learning models to optimize the individualized energy delivery for septic patients. Methods and Study Design: We conducted a study of adult septic patients in Intensive Care Unit (ICU),…

其他定量生物学 · 定量生物学 2024-02-06 Lu Wang , Li Chang , Ruipeng Zhang , Kexun Li , Yu Wang , Wei Chen , Xuanlin Feng , Mingwei Sun , Qi Wang , Charles Damien Lu , Jun Zeng , Hua Jiang

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

机器学习 · 计算机科学 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

机器学习 · 计算机科学 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

Within the intensive care unit (ICU), a wealth of patient data, including clinical measurements and clinical notes, is readily available. This data is a valuable resource for comprehending patient health and informing medical decisions, but…

机器学习 · 计算机科学 2023-12-13 Ryan King , Tianbao Yang , Bobak Mortazavi

Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

机器学习 · 计算机科学 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

People with type 1 diabetes (T1D) struggle to calculate the optimal insulin dose at mealtime, especially when under multiple daily injections (MDI) therapy. Effectively, they will not always perform rigorous and precise calculations, but…

人工智能 · 计算机科学 2023-09-19 Anas El Fathi , Marc D. Breton

This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state…

人工智能 · 计算机科学 2018-01-30 Ning Liu , Ying Liu , Brent Logan , Zhiyuan Xu , Jian Tang , Yanzhi Wang

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

计算机与社会 · 计算机科学 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

This paper presents a real time, data driven decision support framework for epidemic control. We combine a compartmental epidemic model with sequential Bayesian inference and reinforcement learning (RL) controllers that adaptively choose…

统计方法学 · 统计学 2025-11-25 Giacomo Iannucci , Petros Barmpounakis , Alexandros Beskos , Nikolaos Demiris

Clinical diagnostic guidelines outline the key questions to answer to reach a diagnosis. Inspired by guidelines, we aim to develop a model that learns from electronic health records to determine the optimal sequence of actions for accurate…

In both the fields of computer science and medicine there is very strong interest in developing personalized treatment policies for patients who have variable responses to treatments. In particular, I aim to find an optimal personalized…

机器学习 · 计算机科学 2014-07-01 Yousuf M. Soliman

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Background Predicting mortality and resource utilization from electronic health records (EHRs) is challenging yet crucial for optimizing patient outcomes and managing costs in intensive care unit (ICU). Existing approaches predominantly…

计算与语言 · 计算机科学 2025-08-29 Yucheng Ruan , Xiang Lan , Daniel J. Tan , Hairil Rizal Abdullah , Mengling Feng

Deep learning-based recommender models (DLRMs) have become an essential component of many modern recommender systems. Several companies are now building large compute clusters reserved only for DLRM training, driving new interest in cost-…

信息检索 · 计算机科学 2023-08-17 Kabir Nagrecha , Lingyi Liu , Pablo Delgado , Prasanna Padmanabhan
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