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The field of medical diagnosis has undergone a significant transformation with the advent of large language models (LLMs), yet the challenges of interpretability within these models remain largely unaddressed. This study introduces…

计算与语言 · 计算机科学 2024-09-17 Junying Chen , Chi Gui , Anningzhe Gao , Ke Ji , Xidong Wang , Xiang Wan , Benyou Wang

Engineering managers increasingly must decide how to introduce generative artificial intelligence (AI), retrieval-augmented generation, and coding agents into high-risk operational functions without weakening accountability, privacy, cost…

密码学与安全 · 计算机科学 2026-05-12 Elyson A. De La Cruz , Rishikesh Sahay , Md Rasel Al Mamun

Recent studies have shown that Large Language Models (LLMs) can achieve strong reasoning performance by incorporating functional symbolic representations that abstractly describe graph traversal algorithms and step-by-step reasoning in…

人工智能 · 计算机科学 2026-05-28 Phuong Minh Nguyen , Tien Huu Dang , Naoya Inoue

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

人工智能 · 计算机科学 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Clinical AI adoption is hindered by the black-box/grey-box nature of high-performing models, which lack the ontological grounding and narrative transparency required for professional-level explainability. We present NEURON, a neuro-symbolic…

人工智能 · 计算机科学 2026-05-05 Anuradha Chandrasekaran , Dimitrios Zikos , Mutlu Mete , Alan Pang , Brady D. Lund , Kewei Sha

Existing approaches for predictive process monitoring are sub-symbolic, meaning that they learn correlations between descriptive features and a target feature fully based on data, e.g., predicting the surgical needs of a patient based on…

人工智能 · 计算机科学 2026-04-01 Fabrizio De Santis , Gyunam Park , Wil M. P. van der Aalst , Francesco Zanichelli

Minimally invasive surgery has dramatically improved patient operative outcomes, yet identifying safe operative zones remains challenging in critical phases, requiring surgeons to integrate visual cues, procedural phase, and anatomical…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Guanyi Qin , Xiaozhen Wang , Zhu Zhuo , Chang Han Low , Yuancan Xiao , Yibing Fu , Haofeng Liu , Kai Wang , Chunjiang Li , Yueming Jin

Large Language Models (LLMs) have demonstrated impressive capabilities, yet their deployment in high-stakes domains is hindered by inherent limitations in trustworthiness, including hallucinations, instability, and a lack of transparency.…

计算与语言 · 计算机科学 2025-10-21 David Peer , Sebastian Stabinger

There is growing interest in AI systems that support human decision-making in high-stakes domains (e.g., medical diagnosis) to improve decision quality and reduce cognitive load. Mainstream approaches pair human experts with a…

人工智能 · 计算机科学 2026-03-26 Debodeep Banerjee , Stefano Teso , Burcu Sayin , Andrea Passerini

Critically ill patients in regular wards are vulnerable to unanticipated clinical dete- rioration which requires timely transfer to the intensive care unit (ICU). To allow for risk scoring and patient monitoring in such a setting, we…

机器学习 · 计算机科学 2016-11-17 Ahmed M. Alaa , Jinsung Yoon , Scott Hu , Mihaela van der Schaar

As artificial intelligence (AI) systems approach and surpass expert human performance across a broad range of tasks, obtaining high-quality human supervision for evaluation and training becomes increasingly challenging. Our focus is on…

机器学习 · 计算机科学 2026-02-25 Ren Yin , Takashi Ishida , Masashi Sugiyama

Ensuring that critical IoT systems function safely and smoothly depends a lot on finding anomalies quickly. As more complex systems, like smart healthcare, energy grids and industrial automation, appear, it is easier to see the shortcomings…

人工智能 · 计算机科学 2025-10-07 Raghav Sharma , Manan Mehta

As LLM-based systems increasingly operate as agents embedded within human social and technical systems, alignment can no longer be treated as a property of an isolated model, but must be understood in relation to the environments in which…

In traditional logistic regression models, the link function is often assumed to be linear and continuous in predictors. Here, we consider a threshold model that all continuous features are discretized into ordinal levels, which further…

统计方法学 · 统计学 2022-02-18 Yinan Lin , Wen Zhou , Zhi Geng , Gexin Xiao , Jianxin Yin

Language models (LMs) have achieved impressive accuracy across a variety of tasks but remain vulnerable to high-confidence misclassifications, also referred to as unknown unknowns (UUs). These UUs cluster into blind spots in the feature…

计算与语言 · 计算机科学 2024-11-05 Philip Lippmann , Matthijs T. J. Spaan , Jie Yang

We introduce a family of interpretable machine learning models, with two broad additions: Linearised Additive Models (LAMs) which replace the ubiquitous logistic link function in General Additive Models (GAMs); and SubscaleHedge, an expert…

机器学习 · 计算机科学 2022-11-14 Danial Dervovic , Nicolas Marchesotti , Freddy Lecue , Daniele Magazzeni

Logistic regression (LR) is widely used in clinical prediction because it is simple to deploy and easy to interpret. Nevertheless, being a linear model, LR has limited expressive capability and often has unsatisfactory performance.…

机器学习 · 计算机科学 2019-07-31 Zhicheng Cui , Bradley A Fritz , Christopher R King , Michael S Avidan , Yixin Chen

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

This paper establishes the theoretical and practical foundations for using Large Language Models (LLMs) as measurement instruments for latent economic variables -- specifically variables that describe the cognitive content of occupational…

计量经济学 · 经济学 2026-04-06 Cristian Espinal Maya

The increasing use of machine learning in clinical decision support has been limited by the lack of transparency of many high-performing models. In clinical settings, predictions must be interpretable, auditable, and actionable. This study…