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Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity…

信号处理 · 电气工程与系统科学 2024-10-14 Kaizhong Zheng , Shujian Yu , Baojuan Li , Robert Jenssen , Badong Chen

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Given the input graph and its label/property, several key problems of graph learning, such as finding interpretable subgraphs, graph denoising and graph compression, can be attributed to the fundamental problem of recognizing a subgraph of…

机器学习 · 计算机科学 2020-10-13 Junchi Yu , Tingyang Xu , Yu Rong , Yatao Bian , Junzhou Huang , Ran He

Schizophrenia is a severe mental health condition that requires a long and complicated diagnostic process. However, early diagnosis is vital to control symptoms. Deep learning has recently become a popular way to analyse and interpret…

机器学习 · 计算机科学 2022-04-01 Daniel Organisciak , Hubert P. H. Shum , Ephraim Nwoye , Wai Lok Woo

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

定量方法 · 定量生物学 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Recent years have seen a surge in research focused on leveraging graph learning techniques to detect neurodegenerative diseases. However, existing graph-based approaches typically lack the ability to localize and extract the specific brain…

计算机视觉与模式识别 · 计算机科学 2025-06-16 Nguyen Linh Dan Le , Jing Ren , Ciyuan Peng , Chengyao Xie , Bowen Li , Feng Xia

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

机器学习 · 计算机科学 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

Mapping the connectome of the human brain using structural or functional connectivity has become one of the most pervasive paradigms for neuroimaging analysis. Recently, Graph Neural Networks (GNNs) motivated from geometric deep learning…

神经元与认知 · 定量生物学 2022-11-30 Hejie Cui , Wei Dai , Yanqiao Zhu , Xuan Kan , Antonio Aodong Chen Gu , Joshua Lukemire , Liang Zhan , Lifang He , Ying Guo , Carl Yang

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

The emergence of Graph Convolutional Network (GCN) has greatly boosted the progress of graph learning. However, two disturbing factors, noise and redundancy in graph data, and lack of interpretation for prediction results, impede further…

机器学习 · 计算机科学 2021-03-23 Junchi Yu , Tingyang Xu , Yu Rong , Yatao Bian , Junzhou Huang , Ran He

Due to the superior performance of Graph Neural Networks (GNNs) in various domains, there is an increasing interest in the GNN explanation problem "\emph{which fraction of the input graph is the most crucial to decide the model's…

机器学习 · 计算机科学 2022-07-04 Qinghua Zheng , Jihong Wang , Minnan Luo , Yaoliang Yu , Jundong Li , Lina Yao , Xiaojun Chang

Graph neural networks (GNN) have emerged as a popular tool for modelling functional magnetic resonance imaging (fMRI) datasets. Many recent studies have reported significant improvements in disorder classification performance via more…

Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

神经元与认知 · 定量生物学 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical…

计算机视觉与模式识别 · 计算机科学 2024-08-28 Yuhong Jiao , Jiaqing Miao , Jinnan Gong , Hui He , Ping Liang , Cheng Luo , Ying Tan

The success of Graph Neural Networks (GNNs) has led to a need for understanding their decision-making process and providing explanations for their predictions, which has given rise to explainable AI (XAI) that offers transparent…

机器学习 · 计算机科学 2024-02-21 Sangwoo Seo , Sungwon Kim , Chanyoung Park

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

机器学习 · 统计学 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

计算机视觉与模式识别 · 计算机科学 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner
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