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Large language models (LLMs) rely on pretraining on massive and heterogeneous corpora, where training data composition has a decisive impact on training efficiency and downstream generalization under realistic compute and data budget…

计算与语言 · 计算机科学 2026-04-21 Zhuo Chen , Yuxuan Miao , Supryadi , Deyi Xiong

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Planning for both immediate and long-term benefits becomes increasingly important in recommendation. Existing methods apply Reinforcement Learning (RL) to learn planning capacity by maximizing cumulative reward for long-term recommendation.…

信息检索 · 计算机科学 2024-04-29 Wentao Shi , Xiangnan He , Yang Zhang , Chongming Gao , Xinyue Li , Jizhi Zhang , Qifan Wang , Fuli Feng

The goal of personalized medicine is to discover a treatment regimen that optimizes a patient's clinical outcome based on their personal genetic and environmental factors. However, candidate treatments cannot be arbitrarily administered to…

机器学习 · 计算机科学 2026-02-09 Michael S. Yao , Osbert Bastani , Alma Andersson , Tommaso Biancalani , Aïcha Bentaieb , Claudia Iriondo

Large Language Models (LLMs) are increasingly deployed for clinical reasoning tasks, which inherently require eliciting calibrated probabilistic beliefs based on available evidence. However, real-world clinical data are frequently…

人工智能 · 计算机科学 2026-03-19 Yuta Kobayashi , Vincent Jeanselme , Shalmali Joshi

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

计算与语言 · 计算机科学 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Although large language models (LLMs) demonstrate expert-level medical knowledge, aligning their open-ended outputs with fine-grained clinician preferences remains challenging. Existing methods often rely on coarse objectives or unreliable…

人工智能 · 计算机科学 2026-02-12 Shiwei Lyu , Xidong Wang , Lei Liu , Hao Zhu , Chaohe Zhang , Jian Wang , Jinjie Gu , Benyou Wang , Yue Shen

The introduction of large language models (LLMs) has greatly enhanced the capabilities of software agents. Instead of relying on rule-based interactions, agents can now interact in flexible ways akin to humans. However, this flexibility…

Large Language Models (LLMs) have demonstrated remarkable proficiency in automated text annotation within natural language processing. However, their deployment in clinical settings is severely constrained by strict privacy regulations and…

The rapid evolution of Large Language Models (LLMs) has markedly expanded their application across diverse domains, transforming how complex problems are approached and solved. Initially conceived to predict subsequent words in texts, these…

人工智能 · 计算机科学 2024-07-11 Sumedh Rasal , E. J. Hauer

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

This work develops an LLM-based optimization framework ensuring strict constraint satisfaction in network optimization. While LLMs possess contextual reasoning capabilities, existing approaches often fail to enforce constraints, causing…

网络与互联网体系结构 · 计算机科学 2025-09-10 Youngjin Song , Wookjin Lee , Hong Ki Kim , Sang Hyun Lee

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

计算与语言 · 计算机科学 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Managing clinical trial information is currently a significant challenge for the medical industry, as traditional methods are both time-consuming and costly. This paper proposes a simple yet effective methodology to extract and integrate…

人工智能 · 计算机科学 2024-12-20 Berkan Çakır

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

计算与语言 · 计算机科学 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

计算与语言 · 计算机科学 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

The proliferation of large language models (LLMs) has accelerated the adoption of agent-based workflows, where multiple autonomous agents reason, invoke functions, and collaborate to compose complex data pipelines. However, current…

数据库 · 计算机科学 2025-12-15 Zoi Kaoudi , Ioana Giurgiu

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

计算与语言 · 计算机科学 2023-09-08 Supun Manathunga , Isuru Hettigoda