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To build the connectomics map of the brain, we developed a new algorithm that can automatically refine the Membrane Detection Probability Maps (MDPM) generated to perform automatic segmentation of electron microscopy (EM) images. To achieve…

神经与进化计算 · 计算机科学 2015-06-22 Xundong Wu

Neurons, with their elongated, tree-like dendritic and axonal structures, enable efficient signal integration and long-range communication across brain regions. By reconstructing individual neurons' morphology, we can gain valuable insights…

计算机视觉与模式识别 · 计算机科学 2024-11-08 Rubin Zhao , Yang Liu , Shiqi Zhang , Zijian Yi , Yanyang Xiao , Fang Xu , Yi Yang , Pencheng Zhou

Etruscan mirrors constitute a significant category in Etruscan art, characterized by elaborate figurative illustrations featured on their backside. A laborious and costly aspect of their analysis and documentation is the task of manually…

计算机视觉与模式识别 · 计算机科学 2024-12-11 Rafael Sterzinger , Christian Stippel , Robert Sablatnig

Comprehensive, synapse-resolution imaging of the brain will be crucial for understanding neuronal computations and function. In connectomics, this has been the sole purview of volume electron microscopy (EM), which entails an excruciatingly…

图像与视频处理 · 电气工程与系统科学 2023-03-03 Yicong Li , Yaron Meirovitch , Aaron T. Kuan , Jasper S. Phelps , Alexandra Pacureanu , Wei-Chung Allen Lee , Nir Shavit , Lu Mi

In the field of connectomics, neuroscientists seek to identify cortical connectivity comprehensively. Neuronal boundary detection from the Electron Microscopy (EM) images is often done to assist the automatic reconstruction of neuronal…

计算机视觉与模式识别 · 计算机科学 2017-08-01 Wei Shen , Bin Wang , Yuan Jiang , Yan Wang , Alan Yuille

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

计算机视觉与模式识别 · 计算机科学 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

Improvements in text generation technologies such as machine translation have necessitated more costly and time-consuming human evaluation procedures to ensure an accurate signal. We investigate a simple way to reduce cost by reducing the…

计算与语言 · 计算机科学 2022-04-12 Belén Saldías , George Foster , Markus Freitag , Qijun Tan

Connectomics is an emerging field in neuroscience that aims to reconstruct the 3-dimensional morphology of neurons from electron microscopy (EM) images. Recent studies have successfully demonstrated the use of convolutional neural networks…

计算机视觉与模式识别 · 计算机科学 2017-02-27 Shibani Santurkar , David Budden , Alexander Matveev , Heather Berlin , Hayk Saribekyan , Yaron Meirovitch , Nir Shavit

The field of connectomics has recently produced neuron wiring diagrams from relatively large brain regions from multiple animals. Most of these neural reconstructions were computed from isotropic (e.g., FIBSEM) or near isotropic (e.g.,…

The promise of large-scale, high-resolution datasets from Electron Microscopy (EM) and X-ray Microtomography (XRM) lies in their ability to reveal neural structures and synaptic connectivity, which is critical for understanding the brain.…

Electron microscopic connectomics is an ambitious research direction with the goal of studying comprehensive brain connectivity maps by using high-throughput, nano-scale microscopy. One of the main challenges in connectomics research is…

计算机视觉与模式识别 · 计算机科学 2021-04-14 Tran Minh Quan , David G. C. Hildebrand , Won-Ki Jeong

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

计算机视觉与模式识别 · 计算机科学 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Intra-operative ultrasound is an increasingly important imaging modality in neurosurgery. However, manual interaction with imaging data during the procedures, for example to select landmarks or perform segmentation, is difficult and can be…

计算机视觉与模式识别 · 计算机科学 2019-04-19 Julia Rackerseder , Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…

The tracing of neural pathways through large volumes of image data is an incredibly tedious and time-consuming process that significantly encumbers progress in neuroscience. We are exploring deep learning's potential to automate…

计算机视觉与模式识别 · 计算机科学 2018-09-05 Ishtar Nyawira , Kristi Bushman , Iris Qian , Annie Zhang

Brain MR image segmentation is a key task in neuroimaging studies. It is commonly conducted using standard computational tools, such as FSL, SPM, multi-atlas segmentation etc, which are often registration-based and suffer from expensive…

图像与视频处理 · 电气工程与系统科学 2019-08-29 Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

材料科学 · 物理学 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

计算机视觉与模式识别 · 计算机科学 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab