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Quorum sensing is the regulation of gene expression in response to changes in cell density. To measure their cell density, bacterial populations produce and detect diffusible molecules called autoinducers. Individual bacteria internally…

分子网络 · 定量生物学 2017-04-12 Thibaud Taillefumier , Ned S. Wingreen

Bacteria communicate using secreted chemical signaling molecules called autoinducers in a process known as quorum sensing. The quorum-sensing network of the marine bacterium {\it Vibrio harveyi} employs three autoinducers, each known to…

分子网络 · 定量生物学 2009-05-27 Pankaj Mehta , Sidhartha Goyal , Tao Long , Bonnie Bassler , Ned S. Wingreen

The exchange of small molecular signals within microbial populations is generally referred to as quorum sensing (QS). QS is ubiquitous in nature and enables microorganisms to respond to fluctuations in living environments by working…

细胞行为 · 定量生物学 2019-09-16 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang

Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains. There…

分子网络 · 定量生物学 2016-12-28 Tahir I. Yusufaly , James Q. Boedicker

Microbial communities play a significant role in bioremediation,plant growth,human and animal digestion,global elemental cycles including the carbon-cycle,and water treatment.They are also posed to be the engines of renewable energy via…

新兴技术 · 计算机科学 2016-01-12 Nicolò Michelusi , James Boedicker , Mohamed Y. El-Naggar , Urbashi Mitra

Autoinducers are small signaling molecules that mediate intercellular communication in microbial populations and trigger coordinated gene expression via "quorum sensing". Elucidating the mechanisms that control autoinducer production is,…

种群与进化 · 定量生物学 2017-07-26 Matthias Bauer , Johannes Knebel , Matthias Lechner , Peter Pickl , Erwin Frey

The design of biological networks using bacteria as the basic elements of the network is initially motivated by a phenomenon called quorum sensing. Through quorum sensing, each bacterium performs sensing the medium and communicating it to…

信息论 · 计算机科学 2012-05-23 Arash Einolghozati , Mohsen Sardari , Faramarz Fekri

In quorum sensing (QS), bacteria exchange molecular signals to work together. An analytically-tractable model is presented for characterizing QS signal propagation within a population of bacteria and the number of responsive cooperative…

信息论 · 计算机科学 2020-09-03 Yuting Fang , Adam Noel , Andrew W. Eckford , Nan Yang , Jing Guo

The social organization of microorganisms has long been a fascinating and challenging subject in both biology and sociology. In these organisms, the role of the individual is far less dominant than that of the community, which functions as…

生物物理 · 物理学 2025-03-05 Eleonora Alfinito , Matteo Beccaria

In many natural synchronization phenomena, communication between individual elements occurs not directly, but rather through the environment. One of these instances is bacterial quorum sensing, where bacteria release signaling molecules in…

动力系统 · 数学 2015-05-18 Giovanni Russo , Jean-Jacques E. Slotine

Within the context of evolution, an altruistic act that benefits the receiving individual at the expense of the acting individual is a puzzling phenomenon. An extreme form of altruism can be found in colicinogenic E. coli. These suicidal…

神经与进化计算 · 计算机科学 2016-03-31 Anya Elaine Johnson , Eli Strauss , Rodney Pickett , Christoph Adami , Ian Dworkin , Heather J. Goldsby

Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…

分子网络 · 定量生物学 2017-08-02 Tahir Yusufaly , James Q. Boedicker

Quorum sensing is a decentralized biological process, through which a community of cells with no global awareness coordinate their functional behaviors based solely on cell-medium interactions and local decisions. This paper draws…

机器学习 · 计算机科学 2015-10-08 Feng Tan , Jean-Jacques Slotine

"Secrete-and-sense cells" can communicate by secreting a signaling molecule while also producing a receptor that detects the molecule. The cell can potentially "talk" to itself ("self-communication") or talk to neighboring cells with the…

细胞行为 · 定量生物学 2017-08-10 Berkalp A. Doğaner , Lawrence K. Q. Yan , Hyun Youk

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

神经元与认知 · 定量生物学 2017-09-14 Archana Ram , Andrew Lo

Molecular Communication (MC) utilizes chemical molecules to transmit information, introducing innovative strategies for pharmaceutical interventions and enhanced immune system monitoring. This paper explores Molecular communication based…

生物大分子 · 定量生物学 2024-12-31 Shees Zulfiqar , Ozgur B. Akan

Studies on the role of fluctuations in signal propagation and on gene regulation in monoclonal bacterial population have been extensively pursued based on the machinery of two-component system. The bacterial two-component system shows noise…

分子网络 · 定量生物学 2017-01-10 Tarunendu Mapder , Sudip Chattopadhyay , Suman K Banik

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

细胞行为 · 定量生物学 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

We prove a mean-field equation for the dynamics of quorum-sensing microbial populations. In the stochastic many-particle process, individuals of a population produce public good molecules to different degrees. Individual production is…

数学物理 · 物理学 2018-02-16 Erwin Frey , Johannes Knebel , Peter Pickl

Many biological and physical systems exhibit population-density dependent transitions to synchronized oscillations in a process often termed "dynamical quorum sensing". Synchronization frequently arises through chemical communication via…

细胞行为 · 定量生物学 2010-12-23 David J. Schwab , Ania Baetica , Pankaj Mehta
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