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Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

机器学习 · 计算机科学 2024-04-24 Mike Van Ness , Madeleine Udell

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

人工智能 · 计算机科学 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

机器学习 · 计算机科学 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

Survival analysis based on Whole Slide Images (WSIs) is crucial for evaluating cancer prognosis, as they offer detailed microscopic information essential for predicting patient outcomes. However, traditional WSI-based survival analysis…

计算机视觉与模式识别 · 计算机科学 2025-09-22 Zheng Wang , Hong Liu , Zheng Wang , Danyi Li , Min Cen , Baptiste Magnier , Li Liang , Liansheng Wang

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

Interpretability is crucial for doctors, hospitals, pharmaceutical companies and biotechnology corporations to analyze and make decisions for high stakes problems that involve human health. Tree-based methods have been widely adopted for…

机器学习 · 计算机科学 2024-05-24 Rui Zhang , Rui Xin , Margo Seltzer , Cynthia Rudin

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

机器学习 · 计算机科学 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

The importance of explainability in AI has become a pressing concern, for which several explainable AI (XAI) approaches have been recently proposed. However, most of the available XAI techniques are post-hoc methods, which however may be…

机器学习 · 计算机科学 2022-04-15 Leonardo Lucio Custode , Giovanni Iacca

Artificial intelligence supports healthcare professionals with predictive modeling, greatly transforming clinical decision-making. This study addresses the crucial need for fairness and explainability in AI applications within healthcare to…

机器学习 · 计算机科学 2024-11-27 Chia-Hsuan Chang , Xiaoyang Wang , Christopher C. Yang

This paper presents a reproducible and process-aware pipeline for predictive monitoring of clinical pathways. The approach integrates data lifting, temporal reconstruction, event log construction, prefix-based representations, and…

机器学习 · 计算机科学 2026-05-13 Pasquale Ardimento , Mario Luca Bernardi , Marta Cimitile , Samuele Latorre

Survival analysis is a fundamental tool for modeling time-to-event outcomes in healthcare. Recent advances have introduced flexible neural network approaches for improved predictive performance. However, most of these models do not provide…

机器学习 · 统计学 2025-09-10 Mert Ketenci , Vincent Jeanselme , Harry Reyes Nieva , Shalmali Joshi , Noémie Elhadad

Histopathology Whole-Slide Images (WSIs) provide an important tool to assess cancer prognosis in computational pathology (CPATH). While existing survival analysis (SA) approaches have made exciting progress, they are generally limited to…

计算机视觉与模式识别 · 计算机科学 2025-02-12 Pei Liu , Luping Ji , Jiaxiang Gou , Bo Fu , Mao Ye

To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and clinical practice,…

机器学习 · 计算机科学 2019-08-23 William Caicedo-Torres , Jairo Gutierrez

With the spread and rapid advancement of black box machine learning models, the field of interpretable machine learning (IML) or explainable artificial intelligence (XAI) has become increasingly important over the last decade. This is…

Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

机器学习 · 计算机科学 2023-12-12 Chris Solomou

The abundance of modern health data provides many opportunities for the use of machine learning techniques to build better statistical models to improve clinical decision making. Predicting time-to-event distributions, also known as…

机器学习 · 统计学 2020-12-15 Zidi Xiu , Chenyang Tao , Benjamin A. Goldstein , Ricardo Henao

The objective of this proposal is to bridge the gap between Deep Learning (DL) and System Dynamics (SD) by developing an interpretable neural system dynamics framework. While DL excels at learning complex models and making accurate…

机器学习 · 计算机科学 2025-05-21 Riccardo D'Elia

In medicine, survival analysis studies the time duration to events of interest such as mortality. One major challenge is how to deal with multiple competing events (e.g., multiple disease diagnoses). In this work, we propose a…

机器学习 · 计算机科学 2022-06-29 Zifeng Wang , Jimeng Sun

Clinical decision making is challenging because of pathological complexity, as well as large amounts of heterogeneous data generated as part of routine clinical care. In recent years, machine learning tools have been developed to aid this…

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