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Modern microscopy techniques are aimed at imaging an individual molecule at atomic resolution. Here we show that low-energy electrons with kinetic energies of 50-250 eV offer a possibility of overcome the problem of radiation damage, and…

生物物理 · 物理学 2013-05-09 Tatiana Latychevskaia , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

The current state of the art in structural biology is led by NMR, X-ray crystallography and TEM investigations. These powerful tools however all rely on averaging over a large ensemble of molecules. Here, we present an alternative concept…

原子与分子团簇 · 物理学 2015-12-15 Tatiana Latychevskaia , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

Visualizing individual charges confined to molecules and observing their dynamics with high spatial resolution is a challenge for advancing various fields in science, ranging from mesoscopic physics to electron transfer events in biological…

介观与纳米尺度物理 · 物理学 2016-09-19 Tatiana Latychevskaia , Flavio Wicki , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

It has been a general trend to develop low-voltage electron microscopes due to their high imaging contrast of the sample and low radiation damage. Atom-resolved transmission electron microscopes with voltages as low as 15-40 kV have been…

仪器与探测器 · 物理学 2015-12-29 Wei-Tse Chang , Chun-Yueh Lin , Wei-Hao Hsu , Mu-Tung Chang , Yi-Sheng Chen , En-Te Hwu , Ing-Shouh Hwang

While imaging individual atoms can routinely be achieved in high resolution transmission electron microscopy, visualizing the potential distribution of individually charged adsorbates leading to a phase shift of the probing electron wave is…

介观与纳米尺度物理 · 物理学 2017-08-08 Tatiana Latychevskaia , Flavio Wicki , Conrad Escher , Hans-Werner Fink

Imaging single proteins has been a long-standing ambition for advancing various fields in natural science, as for instance structural biology, biophysics and molecular nanotechnology. In particular, revealing the distinct conformations of…

A technique of pulsed low-energy electron holography is introduced that allows for recording highly resolved holograms within reduced exposure times. Therefore, stacks of holograms are accumulated in a pulsed mode with individual…

仪器与探测器 · 物理学 2013-05-27 Matthias Germann , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Motivated by the need for less destructive imaging of nanostructures, we pursue point-source in-line holography (also known as point projection microscopy, or PPM) with very low energy electrons (-100 eV). This technique exploits the recent…

材料科学 · 物理学 2015-05-27 Lucian Livadaru , Josh Mutus , Robert A. Wolkow

Low-energy electrons offer a unique possibility for long exposure imaging of individual biomolecules without significant radiation damage. In addition, low-energy electrons exhibit high sensitivity to local potentials and thus can be…

介观与纳米尺度物理 · 物理学 2019-08-27 Tatiana Latychevskaia , Conrad Escher , William Andregg , Michael Andregg , Hans-Werner Fink

We have imaged a freestanding graphene sheet of 210 nm in diameter with 2 Angstrom resolution by combining coherent diffraction and holography with low-energy electrons. The entire sheet is reconstructed from just a single diffraction…

材料科学 · 物理学 2015-06-15 Jean-Nicolas Longchamp , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Modern structural biology relies on NMR, X-ray crystallography and cryo-electron microscopy for gaining information on biomolecules at nanometer, sub-nanometer or atomic resolution. All these methods, however, require averaging over a vast…

生物物理 · 物理学 2015-10-07 Jean-Nicolas Longchamp , Tatiana Latychevskaia , Conrad Escher , Hans-Werner Fink

Diffraction of atoms from surfaces provides detailed insights into structures, interactions, and dynamical processes. However, currently the method is limited to measurements in reflection - diffraction through materials has only been…

We investigate the possibility of non-destructive electron diffraction imaging of a single molecule to determine its structure. The molecular specimen will be held on a free-standing sheet of graphene. Due to the high conductivity of…

化学物理 · 物理学 2009-11-13 E. E. Fill , F. Krausz , M. Raizen

The process of radiation from high-energy electron in oriented single crystal is considered using the method which permits inseparable consideration of both coherent and incoherent mechanisms of photon emission. The total intensity of…

高能物理 - 唯象学 · 物理学 2008-11-26 V. N. Baier , V. M. Katkov

Holography relies on the interference between a known reference and a signal of interest to reconstruct both the amplitude and phase of that signal. Commonly performed with photons and electrons, it finds numerous applications in imaging,…

The photon hologram of a one-particle density matrix of a photon gas is derived including the case where the energy of a probe photon is above the electron-positron pair creation threshold. The explicit expressions for the holograms of a…

高能物理 - 理论 · 物理学 2026-05-05 P. O. Kazinski , A. A. Sokolov

Low-energy electrons (30-250 eV) have been successfully employed for imaging individual biomolecules. The most simple and elegant design of a low-energy electron microscope for imaging biomolecules is a lensless setup that operates in the…

仪器与探测器 · 物理学 2014-09-05 Tatiana Latychevskaia , Jean-Nicolas Longchamp , Conrad Escher , Hans-Werner Fink

Single-electron detectors are a key component of electron microscopes and advanced electron optics experiments. We present a YAG:Ce scintillator-based single-electron detector with a spatial resolution of 1 micrometer at an electron energy…

仪器与探测器 · 物理学 2025-10-07 Luis Alfredo Ixquiac Méndez , Martino Zanetti , Tilman Kraeft , Thomas Juffmann

An analytical model of a single-atom electron source is presented, where electrons are created by near-threshold photoionization of an isolated atom. The model considers the classical dynamics of the electron just after the photon…

原子物理 · 物理学 2014-07-29 W. J. Engelen , E. J. D. Vredenbregt , O. J. Luiten

We propose a novel approach to site-resolved detection of a 2D gas of ultracold atoms in an optical lattice. A near resonant laser beam is coherently scattered by the atomic array and its interference pattern is holographically recorded by…

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