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Many real-world Electronic Health Record (EHR) data contains a large proportion of missing values. Leaving substantial portion of missing information unaddressed usually causes significant bias, which leads to invalid conclusion to be…

机器学习 · 计算机科学 2020-11-04 Lucas J. Liu , Hongwei Zhang , Jianzhong Di , Jin Chen

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

机器学习 · 计算机科学 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Longitudinal passive sensing enables continuous health prediction, yet models often fail under cross-dataset distribution shifts. Traditional ML overfits cohort-specific artifacts, while Large Language Models (LLMs) struggle to reason…

Large Language Models (LLMs) are increasingly deployed for clinical reasoning tasks, which inherently require eliciting calibrated probabilistic beliefs based on available evidence. However, real-world clinical data are frequently…

人工智能 · 计算机科学 2026-03-19 Yuta Kobayashi , Vincent Jeanselme , Shalmali Joshi

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

人工智能 · 计算机科学 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

A major challenge in embedding or visualizing clinical patient data is the heterogeneity of variable types including continuous lab values, categorical diagnostic codes, as well as missing or incomplete data. In particular, in EHR data,…

Multimodal large language models (MLLMs) trained with visual instruction tuning have achieved strong performance across diverse tasks, yet they remain limited in vision-centric tasks such as object counting or spatial reasoning. We…

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

机器学习 · 计算机科学 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Large Language Models (LLMs) are increasingly deployed in high-stakes decision-making settings such as legal reasoning, where consistency under factually equivalent inputs is critical. However, we find that fact-preserved but differently…

计算与语言 · 计算机科学 2026-05-28 Seojin Hwang , Minju Kim , Junhyuk Choi , JeongHyun Park , Hwanhee Lee

Missing values, irregularly collected samples, and multi-resolution signals commonly occur in multivariate time series data, making predictive tasks difficult. These challenges are especially prevalent in the healthcare domain, where…

The widespread adoption of large language models (LLMs) across industries has increased the demand for high-quality and customizable outputs. However, traditional alignment methods often require retraining large pretrained models, making it…

计算与语言 · 计算机科学 2025-12-16 Yi Liu , Dianqing Liu , Mingye Zhu , Junbo Guo , Yongdong Zhang , Zhendong Mao

Inherently interpretable machine learning (IML) models offer valuable support for clinical decision-making but face challenges when features contain missing values. Traditional approaches, such as imputation or discarding incomplete…

机器学习 · 计算机科学 2025-02-12 Lena Stempfle , Arthur James , Julie Josse , Tobias Gauss , Fredrik D. Johansson

Time series data plays a critical role across diverse domains such as healthcare, energy, and finance, where tasks like classification, anomaly detection, and forecasting are essential for informed decision-making. Recently, large language…

机器学习 · 计算机科学 2024-12-18 Francis Tang , Ying Ding

Medical image analysis requires substantial labeled data for model training, yet expert annotation is expensive and time-consuming. Active learning (AL) addresses this challenge by strategically selecting the most informative samples for…

图像与视频处理 · 电气工程与系统科学 2026-03-06 Ifrat Ikhtear Uddin , Longwei Wang , Xiao Qin , Yang Zhou , KC Santosh

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

机器学习 · 计算机科学 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

Detecting anomalies in time series data is crucial for finance, healthcare, sensor networks, and industrial monitoring applications. However, time series anomaly detection often suffers from sparse labels, complex temporal patterns, and…

机器学习 · 计算机科学 2026-01-07 Bahareh Golchin , Banafsheh Rekabdar , Danielle Justo

Irregularly-sampled time series occur in many domains including healthcare. They can be challenging to model because they do not naturally yield a fixed-dimensional representation as required by many standard machine learning models. In…

机器学习 · 计算机科学 2020-08-19 Steven Cheng-Xian Li , Benjamin M. Marlin

Although LLMs have demonstrated remarkable capabilities in processing and generating textual data, their pre-trained vocabularies are ill-suited for capturing the nuanced temporal dynamics and patterns inherent in time series. The discrete,…

机器学习 · 计算机科学 2024-12-25 Filippos Bellos , Nam H. Nguyen , Jason J. Corso

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

计算机与社会 · 计算机科学 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Due to individual heterogeneity, performance gaps are observed between generic (one-size-fits-all) models and person-specific models in data-driven health applications. However, in real-world applications, generic models are usually more…

机器学习 · 计算机科学 2022-11-23 Zhaoyang Cao , Han Yu , Huiyuan Yang , Akane Sano