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Radiomics-based AI models show promise for breast cancer diagnosis but often lack interpretability, limiting clinical adoption. This study addresses the gap between radiomic features (RF) and the standardized BI-RADS lexicon by proposing a…

Interpretability has become an essential topic for artificial intelligence in some high-risk domains such as healthcare, bank and security. For commonly-used tabular data, traditional methods trained end-to-end machine learning models with…

人工智能 · 计算机科学 2022-08-18 Haixiao Chi , Dawei Wang , Gaojie Cui , Feng Mao , Beishui Liao

In order for machine learning to be deployed and trusted in many applications, it is crucial to be able to reliably explain why the machine learning algorithm makes certain predictions. For example, if an algorithm classifies a given…

机器学习 · 统计学 2018-11-07 Amirata Ghorbani , Abubakar Abid , James Zou

The healthcare industry has been revolutionized by the convergence of Artificial Intelligence of Medical Things (AIoMT), allowing advanced data-driven solutions to improve healthcare systems. With the increasing complexity of Artificial…

计算机视觉与模式识别 · 计算机科学 2024-03-08 Al Amin , Kamrul Hasan , Saleh Zein-Sabatto , Deo Chimba , Imtiaz Ahmed , Tariqul Islam

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

图像与视频处理 · 电气工程与系统科学 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer-aided cancer survival risk prediction plays an important role in the timely treatment of patients. This is a challenging weakly supervised ordinal regression task associated with multiple clinical factors involved such as…

机器学习 · 计算机科学 2024-09-05 Zekang Yang , Hong Liu , Xiangdong Wang

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

计算机视觉与模式识别 · 计算机科学 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

Psychiatric questionnaires are highly context sensitive and often only weakly predict subsequent symptom severity, which makes the prognostic relationship difficult to learn. Although flexible nonlinear models can improve predictive…

机器学习 · 计算机科学 2026-03-02 Eric V. Strobl

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Iain Swift , JingHua Ye

Competing risks are crucial considerations in survival modelling, particularly in healthcare domains where patients may experience multiple distinct event types. We propose CRISP-NAM (Competing Risks Interpretable Survival Prediction with…

机器学习 · 计算机科学 2025-09-26 Dhanesh Ramachandram , Ananya Raval

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

机器学习 · 计算机科学 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

We introduce a reproducible, bias-resistant machine learning framework that integrates domain-informed feature engineering, nested cross-validation, and calibrated decision-threshold optimization for small-sample neuroimaging data.…

机器学习 · 计算机科学 2026-02-04 Jagan Mohan Reddy Dwarampudi , Jennifer L Purks , Joshua Wong , Renjie Hu , Tania Banerjee

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

机器学习 · 计算机科学 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

图像与视频处理 · 电气工程与系统科学 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro