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Skull-stripping is the removal of background and non-brain anatomical features from brain images. While many skull-stripping tools exist, few target pediatric populations. With the emergence of multi-institutional pediatric data acquisition…

图像与视频处理 · 电气工程与系统科学 2025-12-05 William Kelley , Nathan Ngo , Adrian V. Dalca , Bruce Fischl , Lilla Zöllei , Malte Hoffmann

Longitudinal brain analysis is essential for understanding healthy aging and identifying pathological deviations. Longitudinal registration of sequential brain MRI underpins such analyses. However, existing methods are limited by reliance…

图像与视频处理 · 电气工程与系统科学 2026-03-31 Bailiang Jian , Jiazhen Pan , Yitong Li , Fabian Bongratz , Ruochen Li , Daniel Rueckert , Benedikt Wiestler , Christian Wachinger

We investigate a mutual relationship between information and energy during early phase of LTP induction and maintenance in a large-scale system of mutually coupled dendritic spines, with discrete internal states and probabilistic dynamics,…

神经元与认知 · 定量生物学 2024-08-07 Jan Karbowski , Paulina Urban

In this paper, a neuron with nonlinear dendrites (NNLD) and binary synapses that is able to learn temporal features of spike input patterns is considered. Since binary synapses are considered, learning happens through formation and…

神经与进化计算 · 计算机科学 2015-06-18 Subhrajit Roy , Phyo Phyo San , Shaista Hussain , Lee Wang Wei , Arindam Basu

Spiking neural networks (SNNs) are artificial neural networks based on simulated biological neurons and have attracted much attention in recent artificial intelligence technology studies. The dendrites in biological neurons have efficient…

神经元与认知 · 定量生物学 2025-10-14 Wuque Cai , Hongze Sun , Jiayi He , Qianqian Liao , Yunliang Zang , Duo Chen , Dezhong Yao , Daqing Guo

Dynamic Mode Decomposition (DMD) is a data-driven and model-free decomposition technique. It is suitable for revealing spatio-temporal features of both numerically and experimentally acquired data. Conceptually, DMD performs a…

流体动力学 · 物理学 2020-12-18 Tim Krake , Stefan Reinhardt , Marcel Hlawatsch , Bernhard Eberhardt , Daniel Weiskopf

Spiking Neural Networks (SNNs), as one of the algorithmic models in neuromorphic computing, have gained a great deal of research attention owing to temporal information processing capability, low power consumption, and high biological…

神经与进化计算 · 计算机科学 2023-06-07 Chengting Yu , Zheming Gu , Da Li , Gaoang Wang , Aili Wang , Erping Li

A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, discusses similarities between learning dynamics employed in deep…

神经与进化计算 · 计算机科学 2020-05-22 Jacques Kaiser , Hesham Mostafa , Emre Neftci

There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synaptic connection between two neurons. The membrane shape and…

定量方法 · 定量生物学 2026-02-27 Matthew Hur , Thomas Bartol , Padmini Rangamani , Terrence Sejnowski , Eric Mjolsness

The precise timing of spikes emitted by neurons plays a crucial role in shaping the response of efferent biological neurons. This temporal dimension of neural activity holds significant importance in understanding information processing in…

神经元与认知 · 定量生物学 2023-07-27 Antoine Grimaldi , Laurent U Perrinet

With the rapid development of deep learning, Deep Spiking Neural Networks (DSNNs) have emerged as promising due to their unique spike event processing and asynchronous computation. When deployed on neuromorphic chips, DSNNs offer…

神经与进化计算 · 计算机科学 2024-07-15 Hui Xie , Ge Yang , Wenjuan Gao

An open challenge problem at the forefront of modern neuroscience is to obtain a comprehensive mapping of the neural pathways that underlie human brain function; an enhanced understanding of the wiring diagram of the brain promises to lead…

Transient spine enlargement (3-5 min timescale) is an important event associated with the structural plasticity of dendritic spines. Many of the molecular mechanisms associated with transient spine enlargement have been identified…

亚细胞过程 · 定量生物学 2023-07-19 Padmini Rangamani , Michael G. Levy , Shahid M. Khan , George Oster

We introduce a novel approach for predicting the progression of adolescent idiopathic scoliosis from 3D spine models reconstructed from biplanar X-ray images. Recent progress in machine learning have allowed to improve classification and…

机器学习 · 计算机科学 2017-01-25 Samuel Kadoury , William Mandel , Marjolaine Roy-Beaudry , Marie-Lyne Nault , Stefan Parent

Modeling dynamical systems and unraveling their underlying causal relationships is central to many domains in the natural sciences. Various physical systems, such as those arising in cell biology, are inherently high-dimensional and…

Streaming Dynamic Mode Decomposition (sDMD) (Hemati et al., Phys. Fluids 26(2014)) is a low-storage version of Dynamic Mode Decomposition (DMD) (Schmid, J. Fluid Mech. 656 (2010)), a data-driven method to extract spatio-temporal flow…

流体动力学 · 物理学 2022-06-16 Rui Yang , Xuan Zhang , Philipp Reiter , Moritz Linkmann , Detlef Lohse , Olga Shishkina

Behavioural differences across organisms, whether healthy or pathological, are closely tied to the structure of their neural circuits. Yet, the fine-scale synaptic changes that give rise to these variations remain poorly understood, in part…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Samia Mohinta , Daniel Franco-Barranco , Shi Yan Lee , Albert Cardona

Modern computational science and engineering applications are being improved by the advances in scientific machine learning. Data-driven methods such as Dynamic Mode Decomposition (DMD) can extract coherent structures from spatio-temporal…

图形学 · 计算机科学 2022-08-17 Gabriel F. Barros , Malú Grave , José J. Camata , Alvaro L. G. A. Coutinho

Interconnectivity, fault tolerance, and dynamic evolution of the circuitry are long sought-after objectives of bio-inspired engineering. Here, we propose dendritic transistors composed of organic semiconductors as building blocks for…

新兴技术 · 计算机科学 2021-06-14 Matteo Cucchi , Hans Kleemann , Hsin Tseng , Alexander Lee , Karl Leo

Arbor is a software library designed for efficient simulation of large-scale networks of biological neurons with detailed morphological structures. It combines customizable neuronal and synaptic mechanisms with high-performance computing,…

计算工程、金融与科学 · 计算机科学 2026-02-16 Jannik Luboeinski , Sebastian Schmitt , Shirin Shafiee , Thorsten Hater , Fabian Bösch , Christian Tetzlaff