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Individual patient data (IPD) from oncology trials are essential for reliable evidence synthesis but are rarely publicly available, necessitating reconstruction from published Kaplan-Meier (KM) curves. Existing reconstruction methods suffer…

统计方法学 · 统计学 2026-01-23 Lang Lang , Yao Zhao , Qiuxin Gao , Yanxun Xu

Individual patient data (IPD) are essential for statistical inference in clinical research. However, privacy concerns, high data-sharing costs, and restrictive access often make IPD unavailable. Conventional synthetic data generation…

应用统计 · 统计学 2025-09-23 Zixuan Zhao , Zexin Ren , Guannan Zhai , Feifang Hu , Will Ma , En Xie , Qian Shi

Building high-quality knowledge graphs (KGs) from diverse sources requires combining methods for information extraction, data transformation, ontology mapping, entity matching, and data fusion. Numerous methods and tools exist for each of…

人工智能 · 计算机科学 2025-11-25 Marvin Hofer , Erhard Rahm

Decoder-only Transformer models such as GPT have demonstrated exceptional performance in text generation, by autoregressively predicting the next token. However, the efficacy of running GPT on current hardware systems is bounded by low…

硬件体系结构 · 计算机科学 2024-04-16 Yuting Wu , Ziyu Wang , Wei D. Lu

Generative Pre-trained Transformer (GPT) is a state-of-the-art machine learning model capable of generating human-like text through natural language processing (NLP). GPT is trained on massive amounts of text data and uses deep learning…

Handwritten archival tables contain rich historical information, yet transforming them into structured representations, such as Knowledge Graphs, requires integrating table structure recognition, handwriting recognition, and semantic…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Sarah Binta Alam Shoilee , Victor de Boer , Jacco van Ossenbruggen , Susan Legêne

The transition from task-specific artificial intelligence toward general-purpose foundation models raises fundamental questions about their capacity to support the integrated reasoning required in clinical medicine, where diagnosis demands…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Alexandru Florea , Shansong Wang , Mingzhe Hu , Qiang Li , Zach Eidex , Luke del Balzo , Mojtaba Safari , Xiaofeng Yang

Multimodal knowledge graphs (MKGs), which intuitively organize information in various modalities, can benefit multiple practical downstream tasks, such as recommendation systems, and visual question answering. However, most MKGs are still…

人工智能 · 计算机科学 2023-07-10 Ke Liang , Sihang Zhou , Yue Liu , Lingyuan Meng , Meng Liu , Xinwang Liu

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

定量方法 · 定量生物学 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

The vast collection of machine learning records available on the web presents a significant opportunity for meta-learning, where past experiments are leveraged to improve performance. Two crucial meta-learning tasks are pipeline performance…

AutoML systems build machine learning models automatically by performing a search over valid data transformations and learners, along with hyper-parameter optimization for each learner. Many AutoML systems use meta-learning to guide search…

机器学习 · 计算机科学 2022-07-18 Mossad Helali , Essam Mansour , Ibrahim Abdelaziz , Julian Dolby , Kavitha Srinivas

This paper presents an investigation of the capabilities of Generative Pre-trained Transformers (GPTs) to auto-generate graphical process models from multi-modal (i.e., text- and image-based) inputs. More precisely, we first introduce a…

软件工程 · 计算机科学 2024-06-10 Marvin Voelter , Raheleh Hadian , Timotheus Kampik , Marius Breitmayer , Manfred Reichert

Generative artificial intelligence has transformed the generation of synthetic data, providing innovative solutions to challenges like data scarcity and privacy, which are particularly critical in fields such as medicine. However, the…

计算机视觉与模式识别 · 计算机科学 2024-07-31 Eugenio Lomurno , Matteo Matteucci

Applying LLMs to complex industrial processes remains challenging due to the semantic gap between natural language design intents and the rigorous physical logic of engineering. In the field of petroleum refining engineering, a critical…

计算工程、金融与科学 · 计算机科学 2026-05-20 Dongxiao Liu , Yuwen Ding , Xinghai Wei , Jiacheng Ji , Lei Li , Linghui Li , Xiaoyong Li

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

While large language models (LLMs) have made considerable advancements in understanding and generating unstructured text, their application in structured data remains underexplored. Particularly, using LLMs for complex reasoning tasks on…

计算与语言 · 计算机科学 2023-10-18 Jiho Kim , Yeonsu Kwon , Yohan Jo , Edward Choi

In many contexts, we have access to aggregate data, but individual level data is unavailable. For example, medical studies sometimes report only aggregate statistics about disease prevalence because of privacy concerns. Even so, many a time…

机器学习 · 计算机科学 2018-09-18 Sanket Tavarageri , Nag Mani , Anand Ramasubramanian , Jaskiran Kalsi

AI tasks encompass a wide range of domains and fields. While numerous AI models have been designed for specific tasks and applications, they often require considerable human efforts in finding the right model architecture, optimization…

计算与语言 · 计算机科学 2023-05-05 Shujian Zhang , Chengyue Gong , Lemeng Wu , Xingchao Liu , Mingyuan Zhou

Automated Machine Learning encompasses a set of meta-algorithms intended to design and apply machine learning techniques (e.g., model selection, hyperparameter tuning, model assessment, etc.). TPOT, a software for optimizing machine…

机器学习 · 计算机科学 2018-01-16 Unai Garciarena , Alexander Mendiburu , Roberto Santana

Mapping clinical documents to standardised clinical vocabularies is an important task, as it provides structured data for information retrieval and analysis, which is essential to clinical research, hospital administration and improving…

计算与语言 · 计算机科学 2025-09-15 Mingyang Li , Viktor Schlegel , Tingting Mu , Warren Del-Pinto , Goran Nenadic
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