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Atypical mitotic figures (AMFs) represent abnormal cell division associated with poor prognosis. Yet their detection remains difficult due to low prevalence, subtle morphology, and inter-observer variability. The MIDOG 2025 challenge…

图像与视频处理 · 电气工程与系统科学 2025-10-15 Guillaume Balezo , Hana Feki , Raphaël Bourgade , Lily Monnier , Matthieu Blons , Alice Blondel , Etienne Decencière , Albert Pla Planas , Thomas Walter

Atypical mitotic figures (AMFs) are clinically relevant indicators of abnormal cell division, yet their reliable detection remains challenging due to morphological ambiguity and scanner variability. In this work, we investigated three…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Biwen Meng , Xi Long , Jingxin Liu

We present a solution for the MIDOG 2025 Challenge Track~2, addressing binary classification of normal mitotic figures (NMFs) versus atypical mitotic figures (AMFs). The approach leverages pathology-specific foundation model H-optimus-0,…

Atypical mitosis marks a deviation in the cell division process that has been shown be an independent prognostic marker for tumor malignancy. However, atypical mitosis classification remains challenging due to low prevalence, at times…

Atypical mitotic figures (AMFs) are important histopathological markers yet remain challenging to identify consistently, particularly under domain shift stemming from scanner, stain, and acquisition differences. We present a simple…

计算机视觉与模式识别 · 计算机科学 2025-08-29 Kaustubh Atey , Sameer Anand Jha , Gouranga Bala , Amit Sethi

Mitotic figures are classified into typical and atypical variants, with atypical counts correlating strongly with tumor aggressiveness. Accurate differentiation is therefore essential for patient prognostication and resource allocation, yet…

图像与视频处理 · 电气工程与系统科学 2025-09-19 Mieko Ochi , Bae Yuan

The performance of deep learning models is known to scale with data quantity and diversity. In pathology, as in many other medical imaging domains, the availability of labeled images for a specific task is often limited. Self-supervised…

计算机视觉与模式识别 · 计算机科学 2026-02-05 Jonas Ammeling , Jonathan Ganz , Emely Rosbach , Ludwig Lausser , Christof A. Bertram , Katharina Breininger , Marc Aubreville

This paper presents our solution for the MIDOG 2025 Challenge Track 2, which focuses on binary classification of normal mitotic figures (NMFs) versus atypical mitotic figures (AMFs) in histopathological images. Our approach leverages a…

计算机视觉与模式识别 · 计算机科学 2025-08-27 Yosuke Yamagishi , Shouhei Hanaoka

Accurate mitotic figure classification is crucial in computational pathology, as mitotic activity informs cancer grading and patient prognosis. Distinguishing atypical mitotic figures (AMFs), which indicate higher tumor aggressiveness, from…

图像与视频处理 · 电气工程与系统科学 2025-09-04 Hana Feki , Alice Blondel , Thomas Walter

Parameter-efficient fine-tuning (PEFT) that was initially developed for exploiting pre-trained large language models has recently emerged as an effective approach to perform transfer learning on computer vision tasks. However, the…

计算机视觉与模式识别 · 计算机科学 2024-01-23 Chenyu Lian , Hong-Yu Zhou , Yizhou Yu , Liansheng Wang

Mitotic figures (MFs) are relevant biomarkers in tumor grading. Differentiating atypical MFs (AMFs) from normal MFs (NMFs) remains difficult, as manual annotation is time-consuming and subjective. In this work an ensemble of ConvNeXtBase…

计算机视觉与模式识别 · 计算机科学 2025-08-29 Sara Krauss , Ellena Spieß , Daniel Hieber , Frank Kramer , Johannes Schobel , Dominik Müller

Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…

计算机视觉与模式识别 · 计算机科学 2022-12-13 Marc Aubreville , Jonathan Ganz , Jonas Ammeling , Taryn A. Donovan , Rutger H. J. Fick , Katharina Breininger , Christof A. Bertram

Although vision foundation models (VFMs) are increasingly reused for biomedical image analysis, it remains unclear whether the latent representations they provide are general enough to support effective transfer and reuse across…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Caterina Fuster-Barceló , Virginie Uhlmann

Deep learning has driven significant advances in mitotic figure analysis within computational pathology. In this paper, we present our approach to the Mitosis Domain Generalization (MIDOG) 2025 Challenge, which consists of two distinct…

图像与视频处理 · 电气工程与系统科学 2025-09-04 Shuting Xu , Runtong Liu , Zhixuan Chen , Junlin Hou , Hao Chen

With the advent of large pre-trained transformer models, fine-tuning these models for various downstream tasks is a critical problem. Paucity of training data, the existence of data silos, and stringent privacy constraints exacerbate this…

计算机视觉与模式识别 · 计算机科学 2024-07-17 Naif Alkhunaizi , Faris Almalik , Rouqaiah Al-Refai , Muzammal Naseer , Karthik Nandakumar

Automated detection and classification of mitotic figures especially distinguishing atypical from normal remain critical challenges in computational pathology. We present MitoDetect++, a unified deep learning pipeline designed for the MIDOG…

图像与视频处理 · 电气工程与系统科学 2025-09-08 Esha Sadia Nasir , Jiaqi Lv , Mostafa Jahanifar , Shan E Ahmed Raza

Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in the MIDOG 2021 competition. The purpose of the competition…

计算机视觉与模式识别 · 计算机科学 2021-09-28 Maxime W. Lafarge , Viktor H. Koelzer

We present a novel Parameter-Efficient Fine-Tuning (PEFT) method, dubbed as Adaptive Freezing of Low Rank Adaptation (AFLoRA). Specifically, for each pre-trained frozen weight tensor, we add a parallel path of trainable low-rank matrices,…

计算与语言 · 计算机科学 2024-04-17 Zeyu Liu , Souvik Kundu , Anni Li , Junrui Wan , Lianghao Jiang , Peter Anthony Beerel

Unmanned Aerial Vehicles (UAVs) are increasingly used for reforestation and forest monitoring, including seed dispersal in hard-to-reach terrains. However, a detailed understanding of the forest floor remains a challenge due to high natural…

Adapting vision transformer foundation models through parameter-efficient fine-tuning (PEFT) methods has become increasingly popular. These methods optimize a limited subset of parameters, enabling efficient adaptation without the need to…

计算机视觉与模式识别 · 计算机科学 2024-12-02 Son Thai Ly , Hien V. Nguyen
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