相关论文: Learning from Gene Names, Expression Values and Im…

Histopathology, particularly hematoxylin and eosin (H\&E) staining, plays a critical role in diagnosing and characterizing pathological conditions by highlighting tissue morphology. However, H\&E-stained images inherently lack molecular…

In order to understand the complexities of cellular biology, researchers are interested in two important metrics: the genetic expression information of cells and their spatial coordinates within a tissue sample. However, state-of-the art…

High annotation costs are a substantial bottleneck in applying modern deep learning architectures to clinically relevant medical use cases, substantiating the need for novel algorithms to learn from unlabeled data. In this work, we propose…

We develop an approach to learning visual representations that embraces multimodal data, driven by a combination of intra- and inter-modal similarity preservation objectives. Unlike existing visual pre-training methods, which solve a proxy…

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Advanced self-supervised visual representation learning methods rely on the instance discrimination (ID) pretext task. We point out that the ID task has an implicit semantic consistency (SC) assumption, which may not hold in unconstrained…

Humans make extensive use of vision and touch as complementary senses, with vision providing global information about the scene and touch measuring local information during manipulation without suffering from occlusions. While prior work…

The reliance on large-scale datasets and extensive computational resources has become a major barrier to advancing representation learning in vision, especially in data-scarce domains. In this paper, we address the critical question: Can we…

The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…

Histology imaging is an important tool in medical diagnosis and research, enabling the examination of tissue structure and composition at the microscopic level. Understanding the underlying molecular mechanisms of tissue architecture is…

Learning visual representations of medical images (e.g., X-rays) is core to medical image understanding but its progress has been held back by the scarcity of human annotations. Existing work commonly relies on fine-tuning weights…

Self-supervised learning (SSL) methods have become a dominant paradigm for creating general purpose models whose capabilities can be transferred to downstream supervised learning tasks. However, most such methods rely on vast amounts of…

Spatial Transcriptomics (ST) reveals the spatial distribution of gene expression in tissues, offering critical insights into biological processes and disease mechanisms. However, the high cost, limited coverage, and technical complexity of…

In this paper, we investigate self-supervised pre-training methods for document text recognition. Nowadays, large unlabeled datasets can be collected for many research tasks, including text recognition, but it is costly to annotate them.…

Vision-Language Pretraining (VLP) has demonstrated remarkable capabilities in learning visual representations from textual descriptions of images without annotations. Yet, effective VLP demands large-scale image-text pairs, a resource that…

Deep learning models are essential for scene classification, change detection, land cover segmentation, and other remote sensing image understanding tasks. Most backbones of existing remote sensing deep learning models are typically…

Spatial Transcriptomics (ST) provides spatially resolved gene expression profiles within intact tissue architecture, enabling molecular analysis in histological context. However, the high cost, limited throughput, and restricted data…

A key challenge in training neural networks for a given medical imaging task is often the difficulty of obtaining a sufficient number of manually labeled examples. In contrast, textual imaging reports, which are often readily available in…

Spatial Transcriptomics is a groundbreaking technology that integrates histology images with spatially resolved gene expression profiles. Among the various Spatial Transcriptomics techniques available, Visium has emerged as the most widely…

Typical methods for text-to-image synthesis seek to design effective generative architecture to model the text-to-image mapping directly. It is fairly arduous due to the cross-modality translation. In this paper we circumvent this problem…