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Identifying cancer driver genes (CDGs) is essential for understanding cancer mechanisms and developing targeted therapies. Graph neural networks (GNNs) have recently been employed to identify CDGs by capturing patterns in biological…

基因组学 · 定量生物学 2025-10-09 Bang Chen , Lijun Guo , Houli Fan , Wentao He , Rong Zhang

Graph Neural Networks (GNNs) is an architecture for structural data, and has been adopted in a mass of tasks and achieved fabulous results, such as link prediction, node classification, graph classification and so on. Generally, for a…

机器学习 · 计算机科学 2022-05-12 Ye Tang , Xuesong Yang , Xinrui Liu , Xiwei Zhao , Zhangang Lin , Changping Peng

In practical applications, multi-view data depicting objectives from assorted perspectives can facilitate the accuracy increase of learning algorithms. However, given multi-view data, there is limited work for learning discriminative node…

计算机视觉与模式识别 · 计算机科学 2022-11-18 Zhaoliang Chen , Lele Fu , Jie Yao , Wenzhong Guo , Claudia Plant , Shiping Wang

In object detection, non-maximum suppression (NMS) methods are extensively adopted to remove horizontal duplicates of detected dense boxes for generating final object instances. However, due to the degraded quality of dense detection boxes…

计算机视觉与模式识别 · 计算机科学 2023-06-21 Shi-Xue Zhang , Xiaobin Zhu , Jie-Bo Hou , Xu-Cheng Yin

In light of the recent success of Graph Neural Networks (GNNs) and their ability to perform inference on complex data structures, many studies apply GNNs to the task of text classification. In most previous methods, a heterogeneous graph,…

机器学习 · 计算机科学 2024-10-29 Yassine Abbahaddou , Johannes F. Lutzeyer , Michalis Vazirgiannis

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

机器学习 · 计算机科学 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

图像与视频处理 · 电气工程与系统科学 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

Accurate classification of breast cancer histopathology images is pivotal for early oncological diagnosis and therapeutic intervention.However, conventional deep learning architectures often encounter performance degradation under limited…

计算机视觉与模式识别 · 计算机科学 2026-02-11 Lin-Guo Gao , Suxing Liu

Graph-based neural network models are gaining traction in the field of representation learning due to their ability to uncover latent topological relationships between entities that are otherwise challenging to identify. These models have…

图像与视频处理 · 电气工程与系统科学 2023-07-25 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

Accurate brain tumor segmentation from MRI scans is critical for diagnosis and treatment planning. Despite the strong performance of recent deep learning approaches, two fundamental limitations remain: (1) the lack of reliable uncertainty…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Bahram Mohammadi , Yanqiu Wu , Vu Minh Hieu Phan , Sam White , Minh-Son To , Jian Yang , Michael Sheng , Yang Song , Yuankai Qi

Interpretable Graph Neural Networks (GNNs) aim to reveal the underlying reasoning behind model predictions, attributing their decisions to specific subgraphs that are informative. However, existing subgraph-based interpretable methods…

机器学习 · 计算机科学 2025-05-02 Jie Yang , Yuwen Wang , Kaixuan Chen , Tongya Zheng , Yihe Zhou , Zhenbang Xiao , Ji Cao , Mingli Song , Shunyu Liu

The increase in high-dimensional multiomics data demands advanced integration models to capture the complexity of human diseases. Graph-based deep learning integration models, despite their promise, struggle with small patient cohorts and…

机器学习 · 计算机科学 2024-08-07 Sina Tabakhi , Charlotte Vandermeulen , Ian Sudbery , Haiping Lu

Graph-based data present unique challenges and opportunities for machine learning. Graph Neural Networks (GNNs), and especially those algorithms that capture graph topology through message passing for neighborhood aggregation, have been a…

机器学习 · 计算机科学 2024-04-19 Zheyi Qin , Randy Paffenroth , Anura P. Jayasumana

Multimodal brain networks characterize complex connectivities among different brain regions from both structural and functional aspects and provide a new means for mental disease analysis. Recently, Graph Neural Networks (GNNs) have become…

神经元与认知 · 定量生物学 2022-05-25 Yanqiao Zhu , Hejie Cui , Lifang He , Lichao Sun , Carl Yang

Graph Neural Networks (GNNs) show strong expressive power on graph data mining, by aggregating information from neighbors and using the integrated representation in the downstream tasks. The same aggregation methods and parameters for each…

机器学习 · 计算机科学 2022-03-22 Xiaojun Ma , Qin Chen , Yuanyi Ren , Guojie Song , Liang Wang

Predicting the effect of amino acid mutations on enzyme thermodynamic stability (DDG) is fundamental to protein engineering and drug design. While recent deep learning approaches have shown promise, they often process sequence and structure…

机器学习 · 计算机科学 2025-11-10 Abigail Lin

Cancer is responsible for millions of deaths worldwide every year. Although significant progress hasbeen achieved in cancer medicine, many issues remain to be addressed for improving cancer therapy.Appropriate cancer patient stratification…

机器学习 · 计算机科学 2021-01-18 David Oniani , Chen Wang , Yiqing Zhao , Andrew Wen , Hongfang Liu , Feichen Shen

Graph Neural Networks (GNNs) are a promising deep learning approach for circumventing many real-world problems on graph-structured data. However, these models usually have at least one of four fundamental limitations: over-smoothing,…

机器学习 · 计算机科学 2022-10-03 Xun Liu , Alex Hay-Man Ng , Fangyuan Lei , Yikuan Zhang , Zhengmin Li

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

计算机视觉与模式识别 · 计算机科学 2021-01-01 Mo Zhang , Quanzheng Li

In medical image segmentation tasks, Domain Generalization (DG) under the Federated Learning (FL) framework is crucial for addressing challenges related to privacy protection and data heterogeneity. However, traditional federated learning…

计算机视觉与模式识别 · 计算机科学 2025-10-22 Yucheng Song , Chenxi Li , Haokang Ding , Zhining Liao , Zhifang Liao