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Whole-slide image (WSI) analysis plays a crucial role in cancer diagnosis and treatment. In addressing the demands of this critical task, self-supervised learning (SSL) methods have emerged as a valuable resource, leveraging their…

计算机视觉与模式识别 · 计算机科学 2023-12-13 Gia-Bao Le , Van-Tien Nguyen , Trung-Nghia Le , Minh-Triet Tran

The absence of adequately sufficient expert-level tumor annotations hinders the effectiveness of supervised learning based opportunistic cancer screening on medical imaging. Clinical reports (that are rich in descriptive textual details)…

计算机视觉与模式识别 · 计算机科学 2024-05-24 Guangyu Guo , Jiawen Yao , Yingda Xia , Tony C. W. Mok , Zhilin Zheng , Junwei Han , Le Lu , Dingwen Zhang , Jian Zhou , Ling Zhang

Obtaining a large amount of labeled data in medical imaging is laborious and time-consuming, especially for histopathology. However, it is much easier and cheaper to get unlabeled data from whole-slide images (WSIs). Semi-supervised…

图像与视频处理 · 电气工程与系统科学 2020-08-13 Zeyu Gao , Pargorn Puttapirat , Jiangbo Shi , Chen Li

Recent advancements in computational pathology and artificial intelligence have significantly improved whole slide image (WSI) classification. However, the gigapixel resolution of WSIs and the scarcity of manual annotations present…

计算机视觉与模式识别 · 计算机科学 2024-08-26 Mingxi Ouyang , Yuqiu Fu , Renao Yan , ShanShan Shi , Xitong Ling , Lianghui Zhu , Yonghong He , Tian Guan

The integration of artificial intelligence (AI) into pathology is advancing precision medicine by improving diagnosis, treatment planning, and patient outcomes. Digitised whole-slide images (WSIs) capture rich spatial and morphological…

Probe-level models have led to improved performance in microarray studies but the various sources of probe-level contamination are still poorly understood. Data-driven analysis of probe performance can be used to quantify the uncertainty in…

计算工程、金融与科学 · 计算机科学 2013-04-09 Leo Lahti , Laura L. Elo , Tero Aittokallio , Samuel Kaski

Whole slide image (WSI) analysis has become increasingly important in the medical imaging community, enabling automated and objective diagnosis, prognosis, and therapeutic-response prediction. However, in clinical practice, the…

计算机视觉与模式识别 · 计算机科学 2023-08-28 Yanyan Huang , Weiqin Zhao , Shujun Wang , Yu Fu , Yuming Jiang , Lequan Yu

Whole Slide Image (WSI) classification has very significant applications in clinical pathology, e.g., tumor identification and cancer diagnosis. Currently, most research attention is focused on Multiple Instance Learning (MIL) using static…

计算机视觉与模式识别 · 计算机科学 2025-04-17 Jiaxiang Gou , Luping Ji , Pei Liu , Mao Ye

We present a general approach to synthesizing evidence of time-to-event endpoints in meta-analyses of aggregate data (AD). Our work goes beyond most previous meta-analytic research by using reconstructed survival data as a source of…

Pathological images play an essential role in cancer prognosis, while survival analysis, which integrates computational techniques, can predict critical clinical events such as patient mortality or disease recurrence from whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Guo Tang , Songhan Jiang , Jinpeng Lu , Linghan Cai , Yongbing Zhang

The process of digitising histology slides involves multiple factors that can affect a whole slide image's (WSI) final appearance, including the staining protocol, scanner, and tissue type. This variability constitutes a domain shift and…

计算机视觉与模式识别 · 计算机科学 2024-11-26 Manahil Raza , Saad Bashir , Talha Qaiser , Nasir Rajpoot

Using features extracted from networks pretrained on ImageNet is a common practice in applications of deep learning for digital pathology. However it presents the downside of missing domain specific image information. In digital pathology,…

计算机视觉与模式识别 · 计算机科学 2020-01-14 Jacob Gildenblat , Eldad Klaiman

Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Prediction of genetic biomarkers, e.g., microsatellite instability and BRAF in colorectal cancer is crucial for clinical decision making. In this paper, we propose a whole slide image (WSI) based genetic biomarker prediction method via…

图像与视频处理 · 电气工程与系统科学 2024-07-16 Ling Zhang , Boxiang Yun , Xingran Xie , Qingli Li , Xinxing Li , Yan Wang

The abundance of information present in Whole Slide Images (WSIs) renders them an essential tool for survival analysis. Several Multiple Instance Learning frameworks proposed for this task utilize a ResNet50 backbone pre-trained on natural…

图像与视频处理 · 电气工程与系统科学 2025-08-05 Kleanthis Marios Papadopoulos , Tania Stathaki

Despite their prominent performance on tasks such as ROI classification and segmentation, many pathology foundation models remain constrained by a specific input size e.g. 224 x 224, creating substantial inefficiencies when applied to…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Mengxuan Hu , Zihan Guan , John Kang , Sheng Li , Zhongliang Zhou

The expensive fine-grained annotation and data scarcity have become the primary obstacles for the widespread adoption of deep learning-based Whole Slide Images (WSI) classification algorithms in clinical practice. Unlike few-shot learning…

计算机视觉与模式识别 · 计算机科学 2024-10-01 Kexue Fu , Xiaoyuan Luo , Linhao Qu , Shuo Wang , Ying Xiong , Ilias Maglogiannis , Longxiang Gao , Manning Wang

AI-powered Medical Imaging has recently achieved enormous attention due to its ability to provide fast-paced healthcare diagnoses. However, it usually suffers from a lack of high-quality datasets due to high annotation cost, inter-observer…

计算机视觉与模式识别 · 计算机科学 2022-12-06 Ajay Jaiswal , Kumar Ashutosh , Justin F Rousseau , Yifan Peng , Zhangyang Wang , Ying Ding

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Hyperspectral image (HSI) classification presents unique challenges due to its high spectral dimensionality and limited labeled data. Traditional deep learning models often suffer from overfitting and high computational costs.…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Prachet Dev Singh , Shyamsundar Paramasivam , Sneha Barman , Mainak Singha , Ankit Jha , Girish Mishra , Biplab Banerjee