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相关论文: Patient-Zero: Scaling Synthetic Patient Agents to …

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Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing…

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

计算与语言 · 计算机科学 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

计算与语言 · 计算机科学 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald

Since the COVID-19 pandemic, clinicians have seen a large and sustained influx in patient portal messages, significantly contributing to clinician burnout. To the best of our knowledge, there are no large-scale public patient portal…

人工智能 · 计算机科学 2024-11-12 Joseph Gatto , Parker Seegmiller , Timothy E. Burdick , Sarah Masud Preum

AI systems in healthcare research have shown potential to increase patient throughput and assist clinicians, yet progress is constrained by limited access to real patient data. To address this issue, we present a zero-shot, knowledge-guided…

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

机器学习 · 计算机科学 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

The simulation of realistic clinical interactions plays a pivotal role in advancing clinical Large Language Models (LLMs) and supporting medical diagnostic education. Existing approaches and benchmarks rely on generic or LLM-generated…

计算与语言 · 计算机科学 2026-01-19 Shijie Jiang , Zefan Zhang , Kehua Zhu , Tian Bai , Ruihong Zhao

Medical dialogue systems (MDS) enhance patient-physician communication, improve healthcare accessibility, and reduce costs. However, acquiring suitable data to train these systems poses significant challenges. Privacy concerns prevent the…

计算与语言 · 计算机科学 2024-08-13 Trisha Das , Dina Albassam , Jimeng Sun

Clinical Question Answering (QA) systems enable doctors to quickly access patient information from electronic health records (EHRs). However, training these systems requires significant annotated data, which is limited due to the expertise…

计算与语言 · 计算机科学 2024-12-09 Fan Bai , Keith Harrigian , Joel Stremmel , Hamid Hassanzadeh , Ardavan Saeedi , Mark Dredze

Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

计算与语言 · 计算机科学 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Doctor-patient consultations require multi-turn, context-aware communication tailored to diverse patient personas. Training or evaluating doctor LLMs in such settings requires realistic patient interaction systems. However, existing…

人工智能 · 计算机科学 2025-10-30 Daeun Kyung , Hyunseung Chung , Seongsu Bae , Jiho Kim , Jae Ho Sohn , Taerim Kim , Soo Kyung Kim , Edward Choi

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

计算与语言 · 计算机科学 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Large language models (LLMs) are increasingly deployed as agents, expected to decompose goals, invoke tools, and verify results in dynamic environments. Realizing these capabilities requires access to agentic data-structured interaction…

人工智能 · 计算机科学 2025-10-22 Abhigya Verma , Seganrasan Subramanian , Nandhakumar Kandasamy , Naman Gupta

In recent years, with the rapid advancements in large language models (LLMs), achieving excellent empathetic response capabilities has become a crucial prerequisite. Consequently, managing and understanding empathetic datasets have gained…

计算与语言 · 计算机科学 2024-08-13 Hao Liang , Linzhuang Sun , Jingxuan Wei , Xijie Huang , Linkun Sun , Bihui Yu , Conghui He , Wentao Zhang

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

机器学习 · 计算机科学 2023-11-15 Aryan Jadon , Shashank Kumar

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

计算与语言 · 计算机科学 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a…

Artificial Intelligence-Generated Content, a subset of Generative Artificial Intelligence, holds significant potential for advancing the e-health sector by generating diverse forms of data. In this paper, we propose an end-to-end…

机器学习 · 计算机科学 2025-01-29 Tasnim Ahmed , Salimur Choudhury

Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

机器学习 · 计算机科学 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

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