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Recent advances in deep learning have shown that learning robust feature representations is critical for the success of many computer vision tasks, including medical image segmentation. In particular, both transformer and…

计算机视觉与模式识别 · 计算机科学 2025-02-03 David Li , Anvar Kurmukov , Mikhail Goncharov , Roman Sokolov , Mikhail Belyaev

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

医学物理 · 物理学 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Reaction-diffusion models have been proposed for decades to capture the growth of gliomas, the most common primary brain tumours. However, severe limitations regarding the estimation of the initial conditions and parameter values of such…

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

图像与视频处理 · 电气工程与系统科学 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

The magnetic resonance (MR) analysis of brain tumors is widely used for diagnosis and examination of tumor subregions. The overlapping area among the intensity distribution of healthy, enhancing, non-enhancing, and edema regions makes the…

图像与视频处理 · 电气工程与系统科学 2020-06-01 Mohammad Hamghalam , Baiying Lei , Tianfu Wang

Vestibular schwannomas (VS) are benign tumors that are generally managed by active surveillance with MRI examination. To further assist clinical decision-making and avoid overtreatment, an accurate prediction of tumor growth based on…

图像与视频处理 · 电气工程与系统科学 2024-04-05 Yunjie Chen , Jelmer M. Wolterink , Olaf M. Neve , Stephan R. Romeijn , Berit M. Verbist , Erik F. Hensen , Qian Tao , Marius Staring

Gliomas are the most common malignant brain tumourswith intrinsic heterogeneity. Accurate segmentation of gliomas and theirsub-regions on multi-parametric magnetic resonance images (mpMRI)is of great clinical importance, which defines…

图像与视频处理 · 电气工程与系统科学 2019-11-21 Shuo Wang , Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

图像与视频处理 · 电气工程与系统科学 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Denoising Diffusion Probabilistic Models (DDPMs) have recently achieved remarkable results in conditional and unconditional image generation. The pre-trained models can be adapted without further training to different downstream tasks, by…

计算机视觉与模式识别 · 计算机科学 2023-09-19 Asya Grechka , Guillaume Couairon , Matthieu Cord

Brain tumor analysis in Magnetic Resonance Imaging (MRI) is crucial for accurate diagnosis and treatment planning. However, the task remains challenging due to the complexity and variability of tumor appearances, as well as the scarcity of…

图像与视频处理 · 电气工程与系统科学 2024-07-18 Yiqing Shen , Guannan He , Mathias Unberath

This study introduces a novel point-wise diffusion model that processes spatio-temporal points independently to efficiently predict complex physical systems with shape variations. This methodological contribution lies in applying forward…

计算物理 · 物理学 2025-08-05 Jiyong Kim , Sunwoong Yang , Namwoo Kang

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

计算机视觉与模式识别 · 计算机科学 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Clinical diagnostic and treatment decisions rely upon the integration of patient-specific data with clinical reasoning. Cancer presents a unique context that influence treatment decisions, given its diverse forms of disease evolution.…

图像与视频处理 · 电气工程与系统科学 2022-12-23 K. Ruwani M. Fernando , Chris P. Tsokos

Latent diffusion models have emerged as powerful generative models in medical imaging, enabling the synthesis of high quality brain magnetic resonance imaging scans. In particular, predicting the evolution of a patients brain can aid in…

计算机视觉与模式识别 · 计算机科学 2026-04-20 Duy-Phuong Dao , Muhammad Taqiyuddin , Jahae Kim , Sang-Heon Lee , Hye-Won Jung , Jaehoo Choi , Hyung-Jeong Yang

Accurately modeling longitudinal brain MRI progression is crucial for understanding neurodegenerative diseases and predicting individualized structural changes. Existing state-of-the-art approaches, such as Brain Latent Progression (BrLP),…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Cheng Wan , Bahram Jafrasteh , Ehsan Adeli , Miaomiao Zhang , Qingyu Zhao

Automatically segmenting sub-regions of gliomas (necrosis, edema and enhancing tumor) and accurately predicting overall survival (OS) time from multimodal MRI sequences have important clinical significance in diagnosis, prognosis and…

图像与视频处理 · 电气工程与系统科学 2019-12-17 Xiaoqing Guo , Chen Yang , Pak Lun Lam , Peter Y. M. Woo , Yixuan Yuan

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

图像与视频处理 · 电气工程与系统科学 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Glioblastoma (GBM) is an aggressive primary brain tumor with a median survival of approximately 15 months. In clinical practice, the Stupp protocol serves as the standard first-line treatment. However, patients exhibit highly heterogeneous…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Alexandre G. Leclercq , Sébastien Bougleux , Noémie N. Moreau , Alexis Desmonts , Romain Hérault , Aurélien Corroyer-Dulmont

Precise prognostic modeling of glioblastoma (GBM) under varying treatment interventions is essential for optimizing clinical outcomes. While generative AI has shown promise in simulating GBM evolution, existing methods typically treat…

计算机视觉与模式识别 · 计算机科学 2026-03-10 Chenhui Wang , Boyun Zheng , Liuxin Bao , Zhihao Peng , Peter Y. M. Woo , Hongming Shan , Yixuan Yuan

Our objective is the calibration of mathematical tumor growth models from a single multiparametric scan. The target problem is the analysis of preoperative Glioblastoma (GBM) scans. To this end, we present a fully automatic tumor-growth…

医学物理 · 物理学 2020-01-28 Klaudius Scheufele , Shashank Subramanian , George Biros