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Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

计算机视觉与模式识别 · 计算机科学 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

Cell state discovery is crucial for understanding biological systems and enhancing medical outcomes. A key aspect of this process is identifying distinct biomarkers that define specific cell states. However, difficulties arise from the…

人机交互 · 计算机科学 2025-12-19 Rui Sheng , Zelin Zang , Jiachen Wang , Yan Luo , Zixin Chen , Yan Zhou , Shaolun Ruan , Huamin Qu

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

计算机视觉与模式识别 · 计算机科学 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Carcinoma is the prevailing type of cancer and can manifest in various body parts. It is widespread and can potentially develop in numerous locations within the body. In the medical domain, data for carcinoma cancer is often limited or…

计算机视觉与模式识别 · 计算机科学 2024-09-18 Kislay Raj , Teerath Kumar , Alessandra Mileo , Malika Bendechache

To help address the occlusion problem in panoptic segmentation and image understanding, this paper proposes a new large-scale dataset named COCO-OLAC (COCO Occlusion Labels for All Computer Vision Tasks), which is derived from the COCO…

计算机视觉与模式识别 · 计算机科学 2025-01-14 Wenbo Wei , Jun Wang , Abhir Bhalerao

Lung adenocarcinoma is a morphologically heterogeneous disease, characterized by five primary histologic growth patterns. The quantity of these patterns can be related to tumor behavior and has a significant impact on patient prognosis. In…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Arwa Al-Rubaian , Gozde N. Gunesli , Wajd A. Althakfi , Ayesha Azam , Nasir Rajpoot , Shan E Ahmed Raza

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

图像与视频处理 · 电气工程与系统科学 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Computer-aided analysis of biological microscopy data has seen a massive improvement with the utilization of general-purpose deep learning techniques. Yet, in microscopy studies of multi-organism systems, the problem of collision and…

计算机视觉与模式识别 · 计算机科学 2023-10-09 Albert Alonso , Julius B. Kirkegaard

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it is a challenging task due to low availability of public…

图像与视频处理 · 电气工程与系统科学 2023-04-07 Lydia A. Schoenpflug , Maxime W. Lafarge , Anja L. Frei , Viktor H. Koelzer

The medical imaging community generates a wealth of datasets, many of which are openly accessible and annotated for specific diseases and tasks such as multi-organ or lesion segmentation. Current practices continue to limit model training…

图像与视频处理 · 电气工程与系统科学 2024-01-09 Constantin Ulrich , Fabian Isensee , Tassilo Wald , Maximilian Zenk , Michael Baumgartner , Klaus H. Maier-Hein

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) is used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative…

As integrated circuit (IC) dimensions shrink below the lithographic wavelength, optical lithography faces growing challenges from diffraction and process variability. Model-based optical proximity correction (OPC) and inverse lithography…

机器学习 · 计算机科学 2025-12-25 Yuting Hu , Lei Zhuang , Hua Xiang , Jinjun Xiong , Gi-Joon Nam

In digital pathology, cell detection and classification are often prerequisites to quantify cell abundance and explore tissue spatial heterogeneity. However, these tasks are particularly challenging for multiplex immunohistochemistry (mIHC)…

图像与视频处理 · 电气工程与系统科学 2019-08-05 Yeman Brhane Hagos , Priya Lakshmi Narayanan , Ayse U. Akarca , Teresa Marafioti , Yinyin Yuan

Mitotic activity is an important feature for grading several cancer types. Counting mitotic figures (MFs) is a time-consuming, laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and…

Radiologists routinely detect and size lesions in CT to stage cancer and assess tumor burden. To potentially aid their efforts, multiple lesion detection algorithms have been developed with a large public dataset called DeepLesion (32,735…

图像与视频处理 · 电气工程与系统科学 2025-04-09 Peter D. Erickson , Tejas Sudharshan Mathai , Ronald M. Summers

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

计算机视觉与模式识别 · 计算机科学 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…