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Heart failure is typically diagnosed with a global function assessment, such as ejection fraction. However, these metrics have low discriminate power, failing to distinguish different types of this disease. Quantifying local deformations in…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Pablo Arratia López , Hernán Mella , Sergio Uribe , Daniel E. Hurtado , Francisco Sahli Costabal

Active stress models in cardiac biomechanics account for the mechanical deformation caused by muscle activity, thus providing a link between the electrophysiological and mechanical properties of the tissue. The accurate assessment of active…

We propose FiberNet, a method to estimate \emph{in-vivo} the cardiac fiber architecture of the human atria from multiple catheter recordings of the electrical activation. Cardiac fibers play a central role in the electro-mechanical function…

图像与视频处理 · 电气工程与系统科学 2022-07-25 Carlos Ruiz Herrera , Thomas Grandits , Gernot Plank , Paris Perdikaris , Francisco Sahli Costabal , Simone Pezzuto

Physics-Informed Neural Networks (PINNs) are fast becoming an important tool to solve differential equations rapidly and accurately, and to identify the systems parameters that best agree with a given set of measurements. PINNs have been…

This work presents a physics-informed neural network (PINN) based framework to model the strain-rate and temperature dependence of the deformation fields in elastic-viscoplastic solids. To avoid unbalanced back-propagated gradients during…

材料科学 · 物理学 2022-11-24 Rajat Arora , Pratik Kakkar , Biswadip Dey , Amit Chakraborty

The anisotropic structure of the myocardium is a key determinant of the cardiac function. To date, there is no imaging modality to assess in-vivo the cardiac fiber structure. We recently proposed Fibernet, a method for the automatic…

机器学习 · 计算机科学 2024-11-01 Efraín Magaña , Simone Pezzuto , Francisco Sahli Costabal

Accurate myocardial image registration is essential for cardiac strain analysis and disease diagnosis. However, spectral bias in neural networks impedes modeling high-frequency deformations, producing inaccurate, biomechanically implausible…

图像与视频处理 · 电气工程与系统科学 2025-04-28 Bastien C. Baluyot , Marta Varela , Chen Qin

Electroanatomical maps are a key tool in the diagnosis and treatment of atrial fibrillation. Current approaches focus on the activation times recorded. However, more information can be extracted from the available data. The fibers in…

Near-wall blood flow and wall shear stress (WSS) regulate major forms of cardiovascular disease, yet they are challenging to quantify with high fidelity. Patient-specific computational and experimental measurement of WSS suffers from…

流体动力学 · 物理学 2021-07-28 Amirhossein Arzani , Jian-Xun Wang , Roshan M. D'Souza

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Physics-informed neural networks (PINNs) are extensively used to represent various physical systems across multiple scientific domains. The same can be said for cardiac electrophysiology, wherein fully-connected neural networks (FCNNs) have…

计算工程、金融与科学 · 计算机科学 2025-06-19 Roshan Antony Gomez , Julien Stöcker , Barış Cansız , Michael Kaliske

Accurately inferring underlying electrophysiological (EP) tissue properties from action potential recordings is expected to be clinically useful in the diagnosis and treatment of arrhythmias such as atrial fibrillation, but it is…

Elucidating the biomechanical behavior of the myocardium is crucial for understanding cardiac physiology, but cannot be directly inferred from clinical imaging and typically requires finite element (FE) simulations. However, conventional FE…

医学物理 · 物理学 2025-06-27 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

Tracer-kinetic models allow for the quantification of kinetic parameters such as blood flow from dynamic contrast-enhanced magnetic resonance (MR) images. Fitting the observed data with multi-compartment exchange models is desirable, as…

图像与视频处理 · 电气工程与系统科学 2022-04-08 Rudolf L. M. van Herten , Amedeo Chiribiri , Marcel Breeuwer , Mitko Veta , Cian M. Scannell

This study introduces a computational approach leveraging Physics-Informed Neural Networks (PINNs) for the efficient computation of arterial blood flows, particularly focusing on solving the incompressible Navier-Stokes equations by using…

数值分析 · 数学 2024-04-29 Shivam Bhargava , Nagaiah Chamakuri

The strongly-constrained physics-informed neural network (SCPINN) is proposed by adding the information of compound derivative embedded into the soft-constraint of physics-informed neural network(PINN). It is used to predict nonlinear…

斑图形成与孤子 · 物理学 2022-11-30 Yin Fang , Wen-Bo Bo , Ru-Ru Wang , Yue-Yue Wang , Chao-Qing Dai

We introduce an optimized physics-informed neural network (PINN) trained to solve the problem of identifying and characterizing a surface breaking crack in a metal plate. PINNs are neural networks that can combine data and physics in the…

Modeling viscoelastic behavior is crucial in engineering and biomechanics, where materials undergo time-dependent deformations, including stress relaxation, creep buckling and biological tissue development. Traditional numerical methods,…

计算工程、金融与科学 · 计算机科学 2025-12-12 Zhongya Lin , Jinshuai Bai , Shuang Li , Xindong Chen , Bo Li , Xi-Qiao Feng

Rule-based methods are often used for assigning fiber orientation to cardiac anatomical models. However, existing methods have been developed using data mostly from the left ventricle. As a consequence, fiber information obtained from…

Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…

医学物理 · 物理学 2024-01-09 Nathan Dermul , Hans Dierckx
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