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Segmentation of organs or lesions from medical images plays an essential role in many clinical applications such as diagnosis and treatment planning. Though Convolutional Neural Networks (CNN) have achieved the state-of-the-art performance…

计算机视觉与模式识别 · 计算机科学 2021-05-27 Xiangde Luo , Guotai Wang , Tao Song , Jingyang Zhang , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren , Shaoting Zhang

Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in…

图像与视频处理 · 电气工程与系统科学 2020-12-29 Huahong Zhang , Ipek Oguz

Magnetic Resonance Imaging (MRI) is pivotal in radiology, offering non-invasive and high-quality insights into the human body. Precise segmentation of MRIs into different organs and tissues would be highly beneficial since it would allow…

The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

机器学习 · 统计学 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

We propose a new computer aided detection framework for tumours acquired on DCE-MRI (Dynamic Contrast Enhanced Magnetic Resonance Imaging) series on small animals. In this approach we consider DCE-MRI series as multivariate images. A full…

图像与视频处理 · 电气工程与系统科学 2019-10-29 Guillaume Noyel , Jesus Angulo , Dominique Jeulin , Daniel Balvay , Charles-André Cuenod

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

计算机视觉与模式识别 · 计算机科学 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

统计方法学 · 统计学 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

3D microscopy is key in the investigation of diverse biological systems, and the ever increasing availability of large datasets demands automatic cell identification methods that not only are accurate, but also can imply the uncertainty in…

计算机视觉与模式识别 · 计算机科学 2021-02-24 Alvaro Gomariz , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

Through spectral unmixing, hyperspectral imaging (HSI) in fluorescence-guided brain tumor surgery has enabled detection and classification of tumor regions invisible to the human eye. Prior unmixing work has focused on determining a minimal…

图像与视频处理 · 电气工程与系统科学 2024-02-01 David Black , Benoit Liquet , Sadahiro Kaneko , Antonio Di leva , Walter Stummer , Eric Suero Molina

Image segmentation serves as a critical tool across a range of applications, encompassing autonomous driving's pedestrian detection and pre-operative tumor delineation in the medical sector. Among these applications, we focus on the…

图像与视频处理 · 电气工程与系统科学 2023-08-08 Youssef Sultan , Yongqiang Wang , James Scanlon , Lisa D'lima

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

图像与视频处理 · 电气工程与系统科学 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Multi-modal learning is typically performed with network architectures containing modality-specific layers and shared layers, utilizing co-registered images of different modalities. We propose a novel learning scheme for unpaired…

计算机视觉与模式识别 · 计算机科学 2020-01-10 Qi Dou , Quande Liu , Pheng Ann Heng , Ben Glocker

In the past ten years, with the help of deep learning, especially the rapid development of deep neural networks, medical image analysis has made remarkable progress. However, how to effectively use the relational information between various…

计算机视觉与模式识别 · 计算机科学 2023-03-29 Zhihua Liu

Accurate vessel segmentation in X-ray angiograms is crucial for numerous clinical applications. However, the scarcity of annotated data presents a significant challenge, which has driven the adoption of self-supervised learning (SSL)…

计算机视觉与模式识别 · 计算机科学 2025-11-14 De-Xing Huang , Xiao-Hu Zhou , Mei-Jiang Gui , Xiao-Liang Xie , Shi-Qi Liu , Shuang-Yi Wang , Tian-Yu Xiang , Rui-Ze Ma , Nu-Fang Xiao , Zeng-Guang Hou

Super-resolution imaging techniques have largely improved our capabilities to visualize nanometric structures in biological systems. Their application further enables one to potentially quantitate relevant parameters to determine the…

生物物理 · 物理学 2019-12-18 Tina Kosǔta , Marta Cullell-Dalmau , Francesca Cella Zanacchi , Carlo Manzo

Information about the structure and composition of biopsy specimens can assist in disease monitoring and diagnosis. In principle, this can be acquired from Raman and infrared (IR) hyperspectral images (HSIs) that encode information about…

医学物理 · 物理学 2022-09-12 Ciaran Bench , Jayakrupakar Nallala , Chun-Chin Wang , Hannah Sheridan , Nicholas Stone

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by diffuse and focal areas of tissue loss. Conventional MRI techniques such as T1-weighted and T2-weighted scans are generally used in the diagnosis and…

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

Motivation: Understanding the spatial architecture of tissues is essential for decoding the complex interactions within cellular ecosystems and their implications for disease pathology and clinical outcomes. Recent advances in multiplex…

定量方法 · 定量生物学 2025-04-28 Junsouk Choi , Jian Kang , Veerabhadran Baladandayuthapani