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Unsupervised learning enables modeling complex images without the need for annotations. The representation learned by such models can facilitate any subsequent analysis of large image datasets. However, some generative factors that cause…

图像与视频处理 · 电气工程与系统科学 2020-08-27 Maxime W. Lafarge , Josien P. W. Pluim , Mitko Veta

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

计算机视觉与模式识别 · 计算机科学 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

图像与视频处理 · 电气工程与系统科学 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

Given multi-type point maps from different place-types (e.g., tumor regions), our objective is to develop a classifier trained on the source place-type to accurately distinguish between two classes of the target place-type based on their…

机器学习 · 计算机科学 2025-04-25 Majid Farhadloo , Arun Sharma , Alexey Leontovich , Svetomir N. Markovic , Shashi Shekhar

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Automatic and accurate Gleason grading of histopathology tissue slides is crucial for prostate cancer diagnosis, treatment, and prognosis. Usually, histopathology tissue slides from different institutions show heterogeneous appearances…

计算机视觉与模式识别 · 计算机科学 2018-06-08 Jian Ren , Ilker Hacihaliloglu , Eric A. Singer , David J. Foran , Xin Qi

In digital pathology, whole slide images (WSIs) are widely used for applications such as cancer diagnosis and prognosis prediction. Visual transformer models have recently emerged as a promising method for encoding large regions of WSIs…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Shuai Jiang , Liesbeth Hondelink , Arief A. Suriawinata , Saeed Hassanpour

Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide. It is easy to acquire and cost effective, but cells and tissue…

计算机视觉与模式识别 · 计算机科学 2022-07-12 Zhaoyang Xu , Xingru Huang , Carlos Fernández Moro , Béla Bozóky , Qianni Zhang

Existing deep learning-based approaches for histopathology image analysis require large annotated training sets to achieve good performance; but annotating histopathology images is slow and resource-intensive. Conditional generative…

图像与视频处理 · 电气工程与系统科学 2021-10-29 Sujata Butte , Haotian Wang , Min Xian , Aleksandar Vakanski

Molecular testing of tumor samples for targetable biomarkers is restricted by a lack of standardization, turnaround-time, cost, and tissue availability across cancer types. Additionally, targetable alterations of low prevalence may not be…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Kshitij Ingale , Sun Hae Hong , Qiyuan Hu , Renyu Zhang , Bo Osinski , Mina Khoshdeli , Josh Och , Kunal Nagpal , Martin C. Stumpe , Rohan P. Joshi

Obtaining truly representative pore-scale images that match bulk formation properties remains a fundamental challenge in subsurface characterization, as natural spatial heterogeneity causes extracted sub-images to deviate significantly from…

计算机视觉与模式识别 · 计算机科学 2025-10-23 Ali Sadeghkhani , Brandon Bennett , Masoud Babaei , Arash Rabbani

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

图像与视频处理 · 电气工程与系统科学 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

The ability to learn sequentially from different data sites is crucial for a deep network in solving practical medical image diagnosis problems due to privacy restrictions and storage limitations. However, adapting on incoming site leads to…

计算机视觉与模式识别 · 计算机科学 2025-04-28 Dunyuan Xu , Xi Wang , Jingyang Zhang , Pheng-Ann Heng

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

计算机视觉与模式识别 · 计算机科学 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

图像与视频处理 · 电气工程与系统科学 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Neel Dey , Benjamin Billot , Hallee E. Wong , Clinton J. Wang , Mengwei Ren , P. Ellen Grant , Adrian V. Dalca , Polina Golland

Machine learning techniques that perform morphological classification of astronomical sources often suffer from a scarcity of labelled training data. Here, we focus on the case of supervised deep learning models for the morphological…

Given the emergence of deep learning, digital pathology has gained popularity for cancer diagnosis based on histology images. Deep weakly supervised object localization (WSOL) models can be trained to classify histology images according to…

计算机视觉与模式识别 · 计算机科学 2024-05-14 Alexis Guichemerre , Soufiane Belharbi , Tsiry Mayet , Shakeeb Murtaza , Pourya Shamsolmoali , Luke McCaffrey , Eric Granger

Medical image classification is one of the most critical problems in the image recognition area. One of the major challenges in this field is the scarcity of labelled training data. Additionally, there is often class imbalance in datasets…

图像与视频处理 · 电气工程与系统科学 2022-09-29 Khushboo Mehra , Hassan Soliman , Soumya Ranjan Sahoo